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CORDIS

A multidisciplinary approach to cell division: From human oocyte to synthetic biology

Deliverables

Organization of training activities year 1

Organization of training activities year 1, will be reported on the project's website

A 3D rendering pipeline for cytosim

A 3D rendering pipeline for cytosim; open access software development

3-D animated mitotic spindle

3-D animated mitotic spindle; open access digital animation

Organization of training activities year 3
Organization of training activities year 2

Organization of training activities year 2, and documented on the project's website

Publications

Mitotic spindles revisited – new insights from 3D electron microscopy

Author(s): Thomas Müller-Reichert, Robert Kiewisz, Stefanie Redemann
Published in: Journal of Cell Science, Issue 131/3, 2018, Page(s) jcs211383, ISSN 0021-9533
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/jcs.211383

Kinesin-14s and microtubule dynamics define fission yeast mitotic and meiotic spindle assembly and elongation

Author(s): Ana Loncar, Sergio A. Rincon, Manuel Lera Ramirez, Anne Paoletti, Phong T. Tran
Published in: Journal of Cell Science, 2020, Page(s) jcs.240234, ISSN 0021-9533
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/jcs.240234

Self-Organization of Minimal Anaphase Spindle Midzone Bundles

Author(s): Jonathon Hannabuss, Manuel Lera-Ramirez, Nicholas I. Cade, Franck J. Fourniol, François Nédélec, Thomas Surrey
Published in: Current Biology, Issue 29/13, 2019, Page(s) 2120-2130.e7, ISSN 0960-9822
Publisher: Cell Press
DOI: 10.1016/j.cub.2019.05.049

Theory of antiparallel microtubule overlap stabilization by motors and diffusible crosslinkers

Author(s): Manuel Lera‐Ramirez, François J. Nédélec
Published in: Cytoskeleton, Issue 76/11-12, 2019, Page(s) 600-610, ISSN 1949-3584
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/cm.21574

Direct observation of dynamic protein interactions involving human microtubules using solid-state NMR spectroscopy

Author(s): Yanzhang Luo, ShengQi Xiang, Peter Jan Hooikaas, Laura van Bezouwen, A. S. Jijumon, Carsten Janke, Friedrich Förster, Anna Akhmanova, Marc Baldus
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-13876-x

ATAT1-enriched vesicles promote microtubule acetylation via axonal transport

Author(s): Aviel Even, Giovanni Morelli, Loïc Broix, Chiara Scaramuzzino, Silvia Turchetto, Ivan Gladwyn-Ng, Romain Le Bail, Michal Shilian, Stephen Freeman, Maria M. Magiera, A. S. Jijumon, Nathalie Krusy, Brigitte Malgrange, Bert Brone, Paula Dietrich, Ioannis Dragatsis, Carsten Janke, Frédéric Saudou, Miguel Weil, Laurent Nguyen
Published in: Science Advances, Issue 5/12, 2019, Page(s) eaax2705, ISSN 2375-2548
Publisher: Science
DOI: 10.1126/sciadv.aax2705

Microtubule-Associated Proteins: Structuring the Cytoskeleton

Author(s): Satish Bodakuntla, A.S. Jijumon, Cristopher Villablanca, Christian Gonzalez-Billault, Carsten Janke
Published in: Trends in Cell Biology, Issue 29/10, 2019, Page(s) 804-819, ISSN 0962-8924
Publisher: Elsevier BV
DOI: 10.1016/j.tcb.2019.07.004

Purification of tubulin with controlled post-translational modifications by polymerization–depolymerization cycles

Author(s): Judith Souphron, Satish Bodakuntla, A. S. Jijumon, Goran Lakisic, Alexis M. Gautreau, Carsten Janke, Maria M. Magiera
Published in: Nature Protocols, Issue 14/5, 2019, Page(s) 1634-1660, ISSN 1754-2189
Publisher: Nature Publishing Group
DOI: 10.1038/s41596-019-0153-7

Central-spindle microtubules are strongly coupled to chromosomes during both anaphase A and anaphase B

Author(s): Che-Hang Yu, Stefanie Redemann, Hai-Yin Wu, Robert Kiewisz, Tae Yeon Yoo, William Conway, Reza Farhadifar, Thomas Müller-Reichert, Daniel Needleman
Published in: Molecular Biology of the Cell, Issue 30/19, 2019, Page(s) 2503-2514, ISSN 1059-1524
Publisher: American Society for Cell Biology
DOI: 10.1091/mbc.e19-01-0074

Male meiotic spindle features that efficiently segregate paired and lagging chromosomes

Author(s): Gunar Fabig, Robert Kiewisz, Norbert Lindow, James A Powers, Vanessa Cota, Luis J Quintanilla, Jan Brugués, Steffen Prohaska, Diana S Chu, Thomas Müller-Reichert
Published in: eLife, Issue 9, 2020, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.50988

Temperature Control for Live-Cell Imaging

Author(s): Pablo Salaverria, Jeremy Cramer, Pierre Gaudriault
Published in: Imaging and Microscopy, 2018
Publisher: Willey group

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