Dissecting active matter: Microscopic origins of macroscopic actomyosin activity

Project Information

MicMactin

Grant agreement ID: 677532

DOI 10.3030/677532

Project closed

EC signature date 18 December 2015

Start date 1 June 2016

End date 31 May 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 491 868,00

EU contribution € 1 491 868,00

Coordinated by

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France

Publications

Peer reviewed articles (20)

Reversal of contractility as a signature of self-organization in cytoskeletal bundles

Author(s): Martin Lenz; Martin Lenz
Published in: ISSN: 2050-084X, Issue 8, 2020, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.17863/cam.50803

Anisotropic ESCRT-III architecture governs helical membrane tube formation

Author(s): Joachim Moser von Filseck, Luca Barberi, Nathaniel Talledge, Isabel Johnson, Adam Frost, Martin Lenz, Aurélien Roux
Published in: Nature Communications, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-15327-4

Actin dynamics drive cell-like membrane deformation

Author(s): Camille Simon, Remy Kusters, Valentina Caorsi, Antoine Allard, Majdouline Abou-Ghali, John Manzi, Aurelie Di Cicco, Daniel Levy, Martin Lenz, Jean-Francois Joanny, Clement Campillo, Julie Plastino, Pierre Sens, Cecile Sykes
Published in: Nature Physics, 2019, ISSN 1745-2473
Publisher: Nature Publishing Group
DOI: 10.1038/s41567-019-0464-1

Quantitative coupling of cell volume and membrane tension during osmotic shocks

Author(s): Chloe Roffay, Guillaume Molinard, Kyoohyun Kim, Victoria Barbarassa, Marta Urbanska, Vincent Mercier, Jose Garcia Calvo, Stefan Matile, Jochen Guck, Martin Lenz, Aurélien Roux
Published in: Proceedings of the National Academy of Sciences of the United States of America, 2021, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2103228118

Spontaneous rotation can stabilise ordered chiral active fluids

Author(s): Maitra, Ananyo; Lenz, Martin
Published in: Nature Communications, Issue 13, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-08914-7

Chiral Active Hexatics: Giant Number Fluctuations, Waves, and Destruction of Order.

Author(s): Ananyo Maitra; Martin Lenz; Martin Lenz; Raphaël Voituriez
Published in: Physical Review Letters, Issue 2, 2020, ISSN 0031-9007
Publisher: American Physical Society
DOI: 10.1103/physrevlett.125.238005

Local structure of DNA toroids reveals curvature-dependent intermolecular forces

Author(s): Luca Barberi, Françoise Livolant, Amélie Leforestier, Martin Lenz
Published in: Nucleic Acids Research, 2021, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkab197

Swimmer suspensions on substrates: anomalous stability and long-range order

Author(s): Ananyo Maitra, Pragya Srivastava, M. Cristina Marchetti, Sriram Ramaswamy, Martin Lenz
Published in: Physical Review Letters, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1103/physrevlett.124.028002

Mapping and modeling the nanomechanics of bare and protein-coated lipid nanotubes

Author(s): Guillaume Lamour, Antoine Allard, Juan Pelta, Sid Labdi, Martin Lenz, Clément Campillo
Published in: Physical Review X, 2020, ISSN 2160-3308
Publisher: American Physical Society
DOI: 10.1103/physrevx.10.011031

Fiber networks amplify active stress

Author(s): Pierre Ronceray, Chase P. Broedersz, Martin Lenz
Published in: Proceedings of the National Academy of Sciences, Issue 113/11, 2016, Page(s) 2827-2832, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1514208113

Adaptive Response of Actin Bundles under Mechanical Stress

Author(s): Florian Rückerl, Martin Lenz, Timo Betz, John Manzi, Jean-Louis Martiel, Mahassine Safouane, Rajaa Paterski-Boujemaa, Laurent Blanchoin, Cécile Sykes
Published in: Biophysical Journal, Issue 113/5, 2017, Page(s) 1072-1079, ISSN 0006-3495
Publisher: Biophysical Society
DOI: 10.1016/j.bpj.2017.07.017

Geometrical frustration yields fibre formation in self-assembly

Author(s): Martin Lenz, Thomas A. Witten
Published in: Nature Physics, Issue 13/11, 2017, Page(s) 1100-1104, ISSN 1745-2473
Publisher: Nature Publishing Group
DOI: 10.1038/nphys4184

The dynamics of filament assembly define cytoskeletal network morphology

Author(s): Giulia Foffano, Nicolas Levernier, Martin Lenz
Published in: Nature Communications, Issue 7, 2016, Page(s) 13827, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/ncomms13827

Fiber plucking by molecular motors yields large emergent contractility in stiff biopolymer networks

Author(s): Pierre Ronceray, Chase P. Broedersz, Martin Lenz
Published in: Soft Matter, 2019, ISSN 1744-683X
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8sm00979a

A nonequilibrium force can stabilize 2D active nematics

Author(s): Ananyo Maitra, Pragya Srivastava, M. Cristina Marchetti, Juho S. Lintuvuori, Sriram Ramaswamy, Martin Lenz
Published in: Proceedings of the National Academy of Sciences, Issue 115/27, 2018, Page(s) 6934-6939, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1720607115

Stress-dependent amplification of active forces in nonlinear elastic media

Author(s): Pierre Ronceray, Chase P. Broedersz, Martin Lenz
Published in: Soft Matter, Issue 15/2, 2019, Page(s) 331-338, ISSN 1744-683X
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8sm00949j

Modulation of formin processivity by profilin and mechanical tension

Author(s): Cao, Luyan; Kerleau, Mikael; Suzuki, Emiko L.; Wioland, Hugo; Jouet, Sandy; Guichard, Berengere; Lenz, Martin; Romet-Lemonne, Guillaume; Jegou, Antoine
Published in: eLife, Issue 7, 2018, Page(s) e34176, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.1101/235333

Cell contraction induces long-ranged stress stiffening in the extracellular matrix

Author(s): Yu Long Han, Pierre Ronceray, Guoqiang Xu, Andrea Malandrino, Roger D. Kamm, Martin Lenz, Chase P. Broedersz, Ming Guo
Published in: Proceedings of the National Academy of Sciences, Issue 115/16, 2018, Page(s) 4075-4080, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1722619115

Twist-induced local curvature of filaments in DNA toroids

Author(s): Luca Barberi, Martin Lenz
Published in: Il Nuovo Cimento C, 2021, ISSN 2037-4909
Publisher: Italian Society of Physics
DOI: 10.1393/ncc/i2021-21123-5

Actin modulates shape and mechanics of tubular membranes

Author(s): Antoine Allard; Antoine Allard; Mehdi Bouzid; Timo Betz; Camille Simon; Majdouline Abou-Ghali; Joël Lemière; Fabrice Valentino; John Manzi; Françoise Brochard-Wyart; Karine Guevorkian; Julie Plastino; Martin Lenz; Martin Lenz; Clément Campillo; Cécile Sykes
Published in: Allard , A , Bouzid , M , Betz , T , Simon , C , Abou-Ghali , M , Lemiere , J , Valentino , F , Manzi , J , Brochard-Wyart , F , Guevorkian , K , Plastino , J , Lenz , M , Campillo , C & Sykes , C 2020 , ' Actin modulates shape and mechanics of tubular membranes ' , Science Advances , vol. 6 , no. 17 , eaaz3050 . https://doi.org/10.1126/sciadv.aaz3050, Issue 4, 2020, ISSN 1745-2473
Publisher: Nature Publishing Group
DOI: 10.1101/712505

Other (2)

Vimentin intermediate filament assembly is a reversible process

Author(s): Quang Duc Tran, Valerio Sorichetti, Gerard Pehau-Arnaudet, Martin Lenz, Cecile Leduc
Published in: bioRxiv, 2022
Publisher: bioRxiv

Valence can control the non-exponential viscoelastic relaxation of reversible multivalent gels

Author(s): Hugo Le Roy, Jake Song, Gareth H. McKinley, Niels Holten-Andersen, Martin Lenz
Published in: 2021
Publisher: arXiv