Neogenesis of new functional Beta Cells through Modulation of Neurogenin-3 Expression to provide Regenerative Therapy for Diabetes Patients

Project Information

Neobetacell

Grant agreement ID: 677555

DOI

10.3030/677555

Project terminated on 22 April 2021

EC signature date 1 September 2016

Start date 1 October 2016

End date 30 September 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 499 875,00

EU contribution

€ 1 499 875,00

Coordinated by

VRIJE UNIVERSITEIT BRUSSEL
Belgium

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (6)

Human pancreatic neuro-insular network in health and fatty infiltration

Author(s): Shiue-Cheng Tang, Luc Baeyens, Chia-Ning Shen, Shih-Jung Peng, Hung-Jen Chien, David W. Scheel, Chester E. Chamberlain, Michael S. German
Published in: Diabetologia, Issue 61/1, 2018, Page(s) 168-181, ISSN 0012-186X
Publisher: Springer Verlag
DOI: 10.1007/s00125-017-4409-x

A Whole-Genome RNA Interference Screen Reveals a Role for Spry2 in Insulin Transcription and the Unfolded Protein Response

Author(s): Zachary Pappalardo, Deeksha Gambhir Chopra, Thomas G. Hennings, Hunter Richards, Justin Choe, Katherine Yang, Luc Baeyens, Kenny Ang, Steven Chen, Michelle Arkin, Michael S. German, Michael T. McManus, Gregory M. Ku
Published in: Diabetes, Issue 66/6, 2017, Page(s) 1703-1712, ISSN 0012-1797
Publisher: American Diabetes Association
DOI: 10.2337/db16-0962

Semi-automated digital measurement as the method of choice for beta cell mass analysis

Author(s): Violette Coppens, Gunter Leuckx, Yves Heremans, Willem Staels, Yannick Verdonck, Luc Baeyens, Nico De Leu, Harry Heimberg
Published in: PLOS ONE, Issue 13/2, 2018, Page(s) e0191249, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0191249

(Re)generating Human Beta Cells: Status, Pitfalls, and Perspectives

Author(s): Luc Baeyens, Marie Lemper, Willem Staels, Sofie De Groef, Nico De Leu, Yves Heremans, Michael S. German, Harry Heimberg
Published in: Physiological Reviews, Issue 98/3, 2018, Page(s) 1143-1167, ISSN 0031-9333
Publisher: American Physiological Society
DOI: 10.1152/physrev.00034.2016

ROBO2 is a stroma suppressor gene in the pancreas and acts via TGF-β signalling

Author(s): Andreia V. Pinho, Mathias Van Bulck, Lorraine Chantrill, Mehreen Arshi, Tatyana Sklyarova, David Herrmann, Claire Vennin, David Gallego-Ortega, Amanda Mawson, Marc Giry-Laterriere, Astrid Magenau, Gunther Leuckx, Luc Baeyens, Anthony J. Gill, Phoebe Phillips, Paul Timpson, Andrew V. Biankin, Jianmin Wu, Ilse Rooman
Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-018-07497-z

Vegf-A mRNA transfection as a novel approach to improve mouse and human islet graft revascularisation

Author(s): Willem Staels, Yannick Verdonck, Yves Heremans, Gunter Leuckx, Sofie De Groef, Carlo Heirman, Eelco de Koning, Conny Gysemans, Kris Thielemans, Luc Baeyens, Harry Heimberg, Nico De Leu
Published in: Diabetologia, Issue 61/8, 2018, Page(s) 1804-1810, ISSN 0012-186X
Publisher: Springer Verlag
DOI: 10.1007/s00125-018-4646-7