This project achieved a number of major results beyond state of the art, and we were able to develop and commercialize a new software code for analysis of multiple beam interferometry in reflection mode.
1. We could progress from a proof-of principle, towards a working new instrument called the Molecular Forces Apparatus (MFA). With the MFA we can now uniquely demonstrate that we can stabilize the position of two interacting bodies in a force probe experiment to within 8-10 Angstroms in all three spatial dimensions. This is a unique advance, that will allow us now to perform hitherto impossible force probe experiments, with constant distance. As continuing effort we will now enable measuring of single molecular interactions at constant distance at solid/liquid interfaces. The MFA, which we constructed for this unique experiment is at this point in time in the active research state, we performed extensive test force probe experiments. These possibilities are absolutely new and beyond state of the art, as there is currently no other equipment that can perform a similar experiment. As anticipated the developed equipment and software will be the basis for founding a highly competitive and cutting-edge spin-off company with a unique portfolio after the conclusion of this project (based on the submitted patent).
2. Using a newly developed ultra stable model system we were able to unravel competitive effects and scaling effects of adhesive bonding in an aqueous environment. The advances made, allow us now to describe complexity at the molecular scale for predicting macroscopic properties based on single molecular events. For the first time it is now possible to predict a complex situation at a solid liquid interface – based on single molecular data and interaction free energies as they can be measured by experiment. With this result a completely new approach – a molecular interface science – became possible though this action.
3. By now we progressed to a new understanding of the catechol functionality on L-DOPA. Specifically, we can show that this functionality triggers a number of hitherto unexpected side reactions. We have found a surprisingly simple way how these side reactions can be controlled. This opens up the possibility to implement mussel glue principles into technical polymers with full control of the electrochemistry, opening new paths towards wet adhesives with superior performance.
4. A new software analysis tool for white light interferometry, the SFAexplorer, was developed, tested and commercialized in this project. By now, this new tool is licensed by 4 international research institutions spread across the world (Asia, Canada, USA, Europe).
