Single molecule observation and manipulation of gene expression dynamics to dissect mechanisms of cell cycle entry

Project Information

RNAREG

Grant agreement ID: 677936

DOI

10.3030/677936

Project closed

EC signature date 30 November 2015

Start date 1 April 2016

End date 31 August 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 500 000,00

EU contribution

€ 1 500 000,00

Coordinated by

KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (5)

Multi-Color Single-Molecule Imaging Uncovers Extensive Heterogeneity in mRNA Decoding

Author(s): Sanne Boersma, Deepak Khuperkar, Bram M.P. Verhagen, Stijn Sonneveld, Jonathan B. Grimm, Luke D. Lavis, Marvin E. Tanenbaum
Published in: Cell, Issue 178/2, 2019, Page(s) 458-472.e19, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2019.05.001

Translation and Replication Dynamics of Single RNA Viruses

Author(s): Sanne Boersma, Huib H.Rabouw, Lucas J.M. Bruurs, Tonja Pavlovič, Arno L.W.van Vliet, Joep Beumer, Hans Clevers, Frank J.M. van Kuppeveld, Marvin E. Tanenbaum
Published in: Cell, Issue Volume 183, Issue 7, 23 December 2020,, 2020, Page(s) Pages 1930-1945.e23, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2020.10.019

Dynamics of Translation of Single mRNA Molecules In Vivo

Author(s): Xiaowei Yan, Tim A. Hoek, Ronald D. Vale, Marvin E. Tanenbaum
Published in: Cell, Issue 165/4, 2016, Page(s) 976-989, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2016.04.034

Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent

Author(s): Marco Jost, Yuwen Chen, Luke A. Gilbert, Max A. Horlbeck, Lenno Krenning, Grégory Menchon, Ankit Rai, Min Y. Cho, Jacob J. Stern, Andrea E. Prota, Martin Kampmann, Anna Akhmanova, Michel O. Steinmetz, Marvin E. Tanenbaum, Jonathan S. Weissman
Published in: Molecular Cell, Issue 68/1, 2017, Page(s) 210-223.e6, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2017.09.012

mRNA structural dynamics shape Argonaute-target interactions

Author(s): Suzan Ruijtenberg, Stijn Sonneveld, Tao Ju Cui, Ive Logister, Dion de Steenwinkel, Yao Xiao, Ian J. MacRae, Chirlmin Joo, and Marvin E. Tanenbaum
Published in: Nature Structural and Molecular biology, Issue Sep;27(9):, 2020, Page(s) 790-801., ISSN 1545-9993
Publisher: Nature Publishing Group
DOI: 10.1038/s41594-020-0461-1