Transcription Factor-mediated Neuronal Cell Fate Programming in Human Stem Cells

Project Information

ProNeurons

Grant agreement ID: 678071

DOI

10.3030/678071

Project closed

EC signature date 18 February 2016

Start date 1 March 2016

End date 28 February 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 495 000,00

EU contribution

€ 1 495 000,00

Coordinated by

TECHNISCHE UNIVERSITAET DRESDEN
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (10)

Automated methods for cell type annotation on scRNA-seq data

Author(s): Giovanni Pasquini, Jesus Eduardo Rojo Arias, Patrick Schäfer, Volker Busskamp
Published in: Computational and Structural Biotechnology Journal, Issue 19, 2021, Page(s) 961-969, ISSN 2001-0370
Publisher: Elsevier B.V.
DOI: 10.1016/j.csbj.2021.01.015

Optogenetics for neural transplant manipulation and functional analysis

Author(s): Rouhollah Habibey, Kritika Sharma, Anka Swiersy, Volker Busskamp
Published in: Biochemical and Biophysical Research Communications, Issue 527/2, 2020, Page(s) 343-349, ISSN 0006-291X
Publisher: Academic Press
DOI: 10.1016/j.bbrc.2020.01.141

Retinal miRNA Functions in Health and Disease

Author(s): Marta Zuzic, Jesus Eduardo Rojo Arias, Stefanie Gabriele Wohl, Volker Busskamp
Published in: Genes, Issue 10/5, 2019, Page(s) 377, ISSN 2073-4425
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes10050377

Functional Maturation of Human Stem Cell-Derived Neurons in Long-Term Cultures

Author(s): Rebecca S. Lam, Felix M. Töpfer, Phillip G. Wood, Volker Busskamp, Ernst Bamberg
Published in: PLOS ONE, Issue 12/1, 2017, Page(s) e0169506, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0169506

On-demand optogenetic activation of human stem-cell-derived neurons

Author(s): Simon D. Klapper, Evelyn J. Sauter, Anka Swiersy, Max A. E. Hyman, Christian Bamann, Ernst Bamberg, Volker Busskamp
Published in: Scientific Reports, Issue 7/1, 2017, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-017-14827-6

Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis

Author(s): Lisa K. Kutsche, Deisy M. Gysi, Joerg Fallmann, Kerstin Lenk, Rebecca Petri, Anka Swiersy, Simon D. Klapper, Karolina Pircs, Shahryar Khattak, Peter F. Stadler, Johan Jakobsson, Katja Nowick, Volker Busskamp
Published in: Cell Systems, Issue 7/4, 2018, Page(s) 438-452.e8, ISSN 2405-4712
Publisher: Elsevier Inc.
DOI: 10.1016/j.cels.2018.08.011

Biophysical Properties of Optogenetic Tools and Their Application for Vision Restoration Approaches

Author(s): Simon D. Klapper, Anka Swiersy, Ernst Bamberg, Volker Busskamp
Published in: Frontiers in Systems Neuroscience, Issue 10, 2016, ISSN 1662-5137
Publisher: Frontiers Research Foundation
DOI: 10.3389/fnsys.2016.00074

Using Transcriptomic Analysis to Assess Double-Strand Break Repair Activity: Towards Precise in Vivo Genome Editing

Author(s): Giovanni Pasquini, Virginia Cora, Anka Swiersy, Kevin Achberger, Lena Antkowiak, Brigitte Müller, Tobias Wimmer, Sabine Anne-Kristin Fraschka, Nicolas Casadei, Marius Ueffing, Stefan Liebau, Knut Stieger, Volker Busskamp
Published in: International Journal of Molecular Sciences, Issue 21/4, 2020, Page(s) 1380, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21041380

Highly Conductive, Stretchable, and Cell‐Adhesive Hydrogel by Nanoclay Doping

Author(s): Christoph Tondera, Teuku Fawzul Akbar, Alvin Kuriakose Thomas, Weilin Lin, Carsten Werner, Volker Busskamp, Yixin Zhang, Ivan R. Minev
Published in: Small, Issue 15/27, 2019, Page(s) 1901406, ISSN 1613-6810
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.201901406

A comprehensive library of human transcription factors for cell fate engineering

Author(s): Alex H. M. Ng, Parastoo Khoshakhlagh, Jesus Eduardo Rojo Arias, Giovanni Pasquini, Kai Wang, Anka Swiersy, Seth L. Shipman, Evan Appleton, Kiavash Kiaee, Richie E. Kohman, Andyna Vernet, Matthew Dysart, Kathleen Leeper, Wren Saylor, Jeremy Y. Huang, Amanda Graveline, Jussi Taipale, David E. Hill, Marc Vidal, Juan M. Melero-Martin, Volker Busskamp, George M. Church
Published in: Nature Biotechnology, 2020, ISSN 1087-0156
Publisher: Nature Publishing Group
DOI: 10.1038/s41587-020-0742-6

Book chapters (1)

Induced Neurons for the Study of Neurodegenerative and Neurodevelopmental Disorders

Author(s): Evelyn J. Sauter, Lisa K. Kutsche, Simon D. Klapper, Volker Busskamp
Published in: Fragile-X Syndrome - Methods and Protocols, Issue 1942, 2019, Page(s) 101-121, ISBN 978-1-4939-9079-5
Publisher: Springer New York
DOI: 10.1007/978-1-4939-9080-1_9

Intellectual Property Rights

Patent (1)

Transcription factors controlling differentiation of stem cells

Application/Publication number: WO2018049382A1 PCT/US2017/051122
Date: 2017-09-12
Applicant(s): TECHNISCHE UNIVERSITAET DRESDEN