Hybrid Optical Interferometry for Quantitative Cancer Cell Diagnosis

Project Information

OptiQ-CanDo

Grant agreement ID: 678316

DOI

10.3030/678316

Project closed

EC signature date 18 February 2016

Start date 1 July 2016

End date 31 December 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 916 250,00

EU contribution

€ 1 916 250,00

Coordinated by

TEL AVIV UNIVERSITY
Israel

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (22)

Cancer-Cell Deep-Learning Classification by Integrating Quantitative-Phase Spatial and Temporal Fluctuations

Author(s): Shani Ben Baruch; Noa Rotman-Nativ; Alon Baram; Hayit Greenspan; Natan T. Shaked
Published in: Cells, Issue 10, 2022, Page(s) 3353, ISSN 2073-4409
Publisher: 2073-4409
DOI: 10.3390/cells10123353

Real‐Time Stain‐Free Classification of Cancer Cells and Blood Cells Using Interferometric Phase Microscopy and Machine Learning

Author(s): Noga Nissim; Matan Dudaie; Itay Barnea; Natan T. Shaked
Published in: Cytometry Part A, Issue 99, 2021, Page(s) 511-523, ISSN 1552-4930
Publisher: London
DOI: 10.1002/cyto.a.24227

Simultaneous three-wavelength unwrapping using external digital holographic multiplexing module.

Author(s): Nir A. Turko; Pinkie J. Eravuchira; Itay Barnea; Natan T. Shaked
Published in: Optics Letters, Issue 43, 2018, Page(s) 1943-1946, ISSN 0146-9592
Publisher: Optical Society of America
DOI: 10.48550/arxiv.1903.12056

PhUn-Net: ready-to-use neural network for unwrapping quantitative phase images of biological cells

Author(s): Gili Dardikman-Yoffe, Darina Roitshtain, Simcha K. Mirsky, Nir A. Turko, Mor Habaza, Natan T. Shaked
Published in: Biomedical Optics Express, Issue 11/2, 2020, Page(s) 1107, ISSN 2156-7085
Publisher: The Optical Society
DOI: 10.1364/boe.379533

Single-exposure full-field multi-depth imaging using low-coherence holographic multiplexing

Author(s): Lauren Wolbromsky; Nir A. Turko; Natan T. Shaked
Published in: Optics Letters, Issue 43, 2018, Page(s) 2046-2049, ISSN 0146-9592
Publisher: Optical Society of America
DOI: 10.1364/ol.43.002046

High-resolution 4-D acquisition of freely swimming human sperm cells without staining

Author(s): Gili Dardikman-Yoffe, Simcha K. Mirsky, Itay Barnea, Natan T. Shaked
Published in: Science Advances, Issue 6/15, 2020, Page(s) eaay7619, ISSN 2375-2548
Publisher: Science AAAS
DOI: 10.1126/sciadv.aay7619

Dynamic Tomographic Phase Microscopy by Double Six-Pack Holography

Author(s): Simcha K. Mirsky; Itay Barnea; Natan T. Shaked
Published in: ACS Photonics, Issue 9, 2022, Page(s) 1295–1303, ISSN 2330-4022
Publisher: American Chemical Society
DOI: 10.1021/acsphotonics.1c01804

Is multiplexed off-axis holography for quantitative phase imaging more spatial bandwidth-efficient than on-axis holography? [Invited].

Author(s): Gili Dardikman; Natan T. Shaked
Published in: Journal of the Optical Society of America A, Issue 36, 2019, Page(s) A1-A11, ISSN 1084-7529
Publisher: Optical Society of America
DOI: 10.1364/josaa.36.0000a1

Simultaneous off-axis multiplexed holography and regular fluorescence microscopy of biological cells

Author(s): Yoav N. Nygate; Gyanendra Singh; Itay Barnea; Natan T. Shaked
Published in: Optics Letters, Issue 43, 2018, Page(s) 2587-2590, ISSN 0146-9592
Publisher: Optical Society of America
DOI: 10.48550/arxiv.1904.01448

Limited-angle tomographic phase microscopy utilizing confocal scanning fluorescence microscopy

Author(s): Rongli Guo; Itay Barnea; Natan T. Shaked
Published in: Biomed Opt Express, Issue 12, 2021, Page(s) 1869–1881, ISSN 2156-7085
Publisher: The Optical Society
DOI: 10.1364/boe.419598

Low-coherence shearing interferometry with constant off-axis angle

Author(s): Rongli Guo, Natan T. Shaked
Published in: Frontiers in Physics, Issue 8, 2020, ISSN 2296-424X
Publisher: Frontiers

Rapid 3D Refractive-Index Imaging of Live Cells in Suspension without Labeling Using Dielectrophoretic Cell Rotation

Author(s): Mor Habaza, Michael Kirschbaum, Christian Guernth-Marschner, Gili Dardikman, Itay Barnea, Rafi Korenstein, Claus Duschl, Natan T. Shaked
Published in: Advanced Science, Issue 4/2, 2017, Page(s) 1600205, ISSN 2198-3844
Publisher: WILEY-VCH Verlag GmbH & Co. KGaA
DOI: 10.1002/advs.201600205

Angular phase unwrapping of optically thick objects with a thin dimension

Author(s): Gili Dardikman, Simcha Mirsky, Mor Habaza, Yael Roichman, Natan T. Shaked
Published in: Optics Express, Issue 25/4, 2017, Page(s) 3347, ISSN 1094-4087
Publisher: Optical Society of America
DOI: 10.1364/OE.25.003347

Optimal spatial bandwidth capacity in multiplexed off-axis holography for rapid quantitative phase reconstruction and visualization

Author(s): Gili Dardikman, Nir A. Turko, Noa Nativ, Simcha K. Mirsky, Natan T. Shaked
Published in: Optics Express, Issue 25/26, 2017, Page(s) 33400, ISSN 1094-4087
Publisher: Optical Society of America
DOI: 10.1364/OE.25.033400

TOP-GAN: Stain-free cancer cell classification using deep learning with a small training set.

Author(s): Moran Rubin; Omer Stein; Nir A. Turko; Yoav N. Nygate; Darina Roitshtain; Lidor Karako; Itay Barnea; Raja Giryes; Natan T. Shaked
Published in: Medical Image Analysis, Issue 57, 2020, Page(s) 176-185, ISSN 1361-8415
Publisher: Elsevier BV
DOI: 10.1016/j.media.2019.06.014

Four dimensional phase unwrapping of dynamic objects in digital holography

Author(s): Gili Dardikman; Gyanendra Singh; Natan T. Shaked
Published in: Optics Express, Issue 26, 2018, Page(s) 3772-3778, ISSN 1094-4087
Publisher: Optical Society of America
DOI: 10.48550/arxiv.1909.01173

Six-pack off-axis holography

Author(s): Moran Rubin; Gili Dardikman; Simcha K. Mirsky; Nir A. Turko; Natan T. Shaked
Published in: Optics Letters, Issue 42, 2017, Page(s) 4611-4614, ISSN 0146-9592
Publisher: Optical Society of America
DOI: 10.48550/arxiv.1904.01446

Quantitative phase microscopy spatial signatures of cancer cells.

Author(s): Darina Roitshtain; Lauren Wolbromsky; Evgeny Bal; Hayit Greenspan; Lisa L. Satterwhite; Natan T. Shaked
Published in: Cytometry Part A, Issue 91, 2017, Page(s) 482-493, ISSN 1552-4930
Publisher: Wiley
DOI: 10.1002/cyto.a.23100

First experimental realization of six-pack holography and its application to dynamic synthetic aperture superresolution

Author(s): Simcha K. Mirsky, Natan T. Shaked
Published in: Optics Express, Issue 27/19, 2019, Page(s) 26708, ISSN 1094-4087
Publisher: Optical Society of America
DOI: 10.1364/oe.27.026708

Simultaneous two-wavelength phase unwrapping using an external module for multiplexing off-axis holography

Author(s): Nir A. Turko; Natan T. Shaked
Published in: Optics Letters, Issue 42, 2017, ISSN 0146-9592
Publisher: Optical Society of America
DOI: 10.48550/arxiv.1904.01445

Erythrocyte volumetric measurements in imaging flow cytometry using simultaneous three-wavelength digital holographic microscopy

Author(s): Nir A. Turko, Natan T. Shaked
Published in: Biomedical Optics Express, Issue 11/11, 2020, Page(s) 6649, ISSN 2156-7085
Publisher: The Optical Society
DOI: 10.1364/boe.404368

Quantitative phase imaging by wide-field interferometry with variable shearing distance uncoupled from the off-axis angle

Author(s): Rongli Guo, Simcha K. Mirsky, Itay Barnea, Matan Dudaie, Natan T. Shaked
Published in: Optics Express, Issue 28/4, 2020, Page(s) 5617, ISSN 1094-4087
Publisher: Optical Society of America
DOI: 10.1364/oe.385437