Quality Control and Maintenance of Synaptic Mitochondria

Project Information

SynapticMitochondria

Grant agreement ID: 679168

DOI 10.3030/679168

Project closed

EC signature date 4 July 2016

Start date 1 September 2016

End date 28 February 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 300 000,00

EU contribution € 1 300 000,00

Coordinated by

INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES
Portugal

Publications

Peer reviewed articles (12)

Mitochondrial biogenesis in neurons: how and where

Author(s): Cardanho-Ramos, Carlos; Morais, Vanessa A.
Published in: International Journal of Molecular Sciences, Vol 22, Iss 13059, p 13059 (2021), Issue 14220067, 2021, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms222313059

A Systematic Pan-Cancer Analysis of Genetic Heterogeneity Reveals Associations with Epigenetic Modifiers

Author(s): Mafalda Ramos de Matos,Ioana Posa,Filipa Sofia Carvalho,Vanessa Alexandra Morais, Ana Rita Grosso, Sérgio Fernandes de Almeida
Published in: Cancers, Issue 20726694, 2019, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11030391

Orchestrating mitochondria in neurons: Cytoskeleton as the conductor.

Author(s): Carlos Cardanho‐Ramos; Andreia Faria‐Pereira; Vanessa Alexandra Morais
Published in: Cytoskeleton, Issue 19493584, 2020, ISSN 1949-3584
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/cm.21585

Synapses: The Brain’s Energy-Demanding Sites

Author(s): Andreia Faria-Pereira; Vanessa A. Morais
Published in: IJMS - International Journal of Molecular Sciences, Issue 14220067, 2022, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23073627

The PINK1-Mediated Crosstalk between Neural Cells and the Underlying Link to Parkinson's Disease

Author(s): Elvira Pequeno Leites, Vanessa Alexandra Morais
Published in: Cells, Issue 20734409, 2022, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells10061395

Intestinal tissue-resident T cell activation depends on metabolite availability

Author(s): Špela Konjar, Cristina Ferreira, Filipa Sofia Carvalho, Patrícia Figueiredo-Campos, Júlia Fanczal, Sofia Ribeiro, Vanessa Alexandra Morais, Marc Veldhoen
Published in: PNAS, Issue 00278424, 2022, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2202144119

PINK1: A Bridge between Mitochondria and Parkinson's Disease

Author(s): Filipa Barroso Gonçalves, Vanessa Alexandra Morais
Published in: Life, Issue 20751729, 2021, ISSN 2075-1729
Publisher: MDPI
DOI: 10.3390/life11050371

Mitochondrial quality control pathways: PINK1 acts as a gatekeeper

Author(s): Elvira P. Leites, Vanessa A. Morais
Published in: Biochemical and Biophysical Research Communications, Issue 500/1, 2018, Page(s) 45-50, ISSN 0006-291X
Publisher: Academic Press
DOI: 10.1016/j.bbrc.2017.06.096

PARL deficiency in mouse causes Complex III defects, coenzyme Q depletion, and Leigh-like syndrome

Author(s): Marco Spinazzi, Enrico Radaelli, Katrien Horré, Amaia M. Arranz, Natalia V. Gounko, Patrizia Agostinis, Teresa Mendes Maia, Francis Impens, Vanessa Alexandra Morais, Guillermo Lopez-Lluch, Lutgarde Serneels, Placido Navas, Bart De Strooper
Published in: Proceedings of the National Academy of Sciences, Issue 116/1, 2019, Page(s) 277-286, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1811938116

Cardiolipin promotes electron transport between ubiquinone and complex I to rescue PINK1 deficiency

Author(s): Melissa Vos, Ann Geens, Claudia Böhm, Liesbeth Deaulmerie, Jef Swerts, Matteo Rossi, Katleen Craessaerts, Elvira P. Leites, Philip Seibler, Aleksandar Rakovic, Thora Lohnau, Bart De Strooper, Sarah-Maria Fendt, Vanessa A. Morais, Christine Klein, Patrik Verstreken
Published in: The Journal of Cell Biology, Issue 216/3, 2017, Page(s) 695-708, ISSN 0021-9525
Publisher: Rockefeller University Press
DOI: 10.1083/jcb.201511044

BrainPhys Neuronal Media Support Physiological Function of Mitochondria in Mouse Primary Neuronal Cultures

Author(s): Andreia Faria-Pereira, Mariana Temido-Ferreira, Vanessa A Morais
Published in: Frontiers in Molecular Neuroscience, Issue 16625099, 2022, ISSN 1662-5099
Publisher: Frontiers Research Foundation
DOI: 10.3389/fnmol.2022.837448

Improving human mesenchymal stem cell-derived hepatic cell energy metabolism by manipulating glucose homeostasis and glucocorticoid signaling

Author(s): Joana Saraiva Rodrigues, Andreia Faria-Pereira, Sérgio Póvoas Camões, Ana Sofia Serras, Vanessa Alexandra Morais, Jorge Lira Ruas, Joana Paiva Miranda
Published in: Frontiers Endocrinol, 2023, ISSN 1664-2392
Publisher: Frontiers Media
DOI: 10.3389/fendo.2022.1043543

Book chapters (1)

Electron Transport Chain

Author(s): L. Aerts, V.A. Morais
Published in: Parkinson's Disease, 2017, Page(s) 41-75, ISBN 9780-128037836
Publisher: Elsevier
DOI: 10.1016/b978-0-12-803783-6.00002-x