The importance of transcriptional coordination during development

Project Information

SYNC_DEV

Grant agreement ID: 679792

DOI

10.3030/679792

Project closed

EC signature date 25 October 2016

Start date 1 January 2017

End date 31 December 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 500 000,00

EU contribution

€ 1 500 000,00

Coordinated by

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (10)

Imaging translation dynamics in live embryos reveals spatial heterogeneities

Author(s): Jeremy Dufourt, Maelle Bellec, Antonio Trullo, Matthieu Dejean, Sylvain De Rossi, Cyril Favard, Mounia Lagha
Published in: Science, Issue 372/6544, 2021, Page(s) 840-844, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abc3483

Quantitative imaging of transcription in living Drosophila embryos reveals the impact of core promoter motifs on promoter state dynamics

Author(s): Virginia L. Pimmett, Matthieu Dejean, Carola Fernandez, Antonio Trullo, Edouard Bertrand, Ovidiu Radulescu, Mounia Lagha
Published in: Nature Communications, Issue 12/1, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-24461-6

The control of transcriptional memory by stable mitotic bookmarking.

Author(s): Bellec M, Dufourt J, Hunt G, Lenden-Hasse H, Trullo A, Zine El Aabidine A, Lamarque M, Gaskill M, Faure-Gautron H, Mannervik M, Harrison M, Andrau JC, Favard C, Radulescu O and Lagha M
Published in: Nature Communications, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-28855-y

Cis-regulatory chromatin loops arise before TADs and gene activation, and are independent of cell fate during early Drosophila development

Author(s): Sergio Martin Espinola, Markus Götz, Maelle Bellec, Olivier Messina, Jean-Bernard Fiche, Christophe Houbron, Matthieu Dejean, Ingolf Reim, Andrés M. Cardozo Gizzi, Mounia Lagha, Marcelo Nollmann
Published in: Nature Genetics, Issue 53/4, 2021, Page(s) 477-486, ISSN 1061-4036
Publisher: Nature Publishing Group
DOI: 10.1038/s41588-021-00816-z

Temporal control of gene expression by the pioneer factor Zelda through transient interactions in hubs

Author(s): Jeremy Dufourt, Antonio Trullo, Jennifer Hunter, Carola Fernandez, Jorge Lazaro, Matthieu Dejean, Lucas Morales, Saida Nait-Amer, Katharine N. Schulz, Melissa M. Harrison, Cyril Favard, Ovidiu Radulescu, Mounia Lagha
Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-018-07613-z

Microscopy-Based Chromosome Conformation Capture Enables Simultaneous Visualization of Genome Organization and Transcription in Intact Organisms

Author(s): Andrés M. Cardozo Gizzi, Diego I. Cattoni, Jean-Bernard Fiche, Sergio M. Espinola, Julian Gurgo, Olivier Messina, Christophe Houbron, Yuki Ogiyama, Giorgio L. Papadopoulos, Giacomo Cavalli, Mounia Lagha, Marcelo Nollmann
Published in: Molecular Cell, Issue 74/1, 2019, Page(s) 212-222.e5, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2019.01.011

Remembering the past: Mitotic bookmarking in a developing embryo

Author(s): Maelle Bellec, Ovidiu Radulescu, Mounia Lagha
Published in: Current Opinion in Systems Biology, Issue 11, 2018, Page(s) 41-49, ISSN 2452-3100
Publisher: Elsevier
DOI: 10.1016/j.coisb.2018.08.003

A Growing Toolbox to Image Gene Expression in Single Cells: Sensitive Approaches for Demanding Challenges

Author(s): Xavier Pichon, Mounia Lagha, Florian Mueller, Edouard Bertrand
Published in: Molecular Cell, Issue 71/3, 2018, Page(s) 468-480, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2018.07.022

MitoTrack, a user-friendly semi-automatic software for lineage tracking in living embryos

Author(s): A Trullo, J Dufourt, M Lagha
Published in: Bioinformatics, 2019, ISSN 1367-4803
Publisher: Oxford University Press
DOI: 10.1093/bioinformatics/btz717

Tyramine induces dynamic RNP granule remodeling and translation activation in the Drosophila brain

Author(s): Nadia Formicola, Marjorie Heim, Jérémy Dufourt, Anne-Sophie Lancelot, Akira Nakamura, Mounia Lagha, Florence Besse
Published in: eLife, Issue 10, 2021, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.65742

Book chapters (1)

Lighting Up Gene Activation in Living Drosophila Embryos

Author(s): Carola Fernandez, Mounia Lagha
Published in: Imaging gene expression, Issue 2019, 2019, Page(s) 6-74, ISSN 78-1-4939-9674-2
Publisher: springer nature
DOI: 10.1007/978-1-4939-9674-2_5