Optimal diversity in immunity – to overcome pathogens and maximize fitness; moving from correlative associations to a more mechanistic understanding using wild songbirds.

Project Information

Optimal-Immunity

Grant agreement ID: 679799

DOI

10.3030/679799

Project closed

EC signature date 18 March 2016

Start date 1 April 2016

End date 30 September 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 498 732,00

EU contribution

€ 1 498 732,00

Coordinated by

LUNDS UNIVERSITET
Sweden

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (9)

Contrasting results from GWAS and QTL mapping on wing length in great reed warblers

Author(s): Bengt Hansson, Hanna Sigeman, Martin Stervander, Maja Tarka, Suvi Ponnikas, Maria Strandh, Helena Westerdahl, Dennis Hasselquist
Published in: Molecular Ecology Resources, Issue 18/4, 2018, Page(s) 867-876, ISSN 1755-098X
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/1755-0998.12785

Avian Neo-Sex Chromosomes Reveal Dynamics of Recombination Suppression and W Degeneration

Author(s): Hanna Sigeman, Maria Strandh, Estelle Proux-Wéra, Verena E Kutschera, Suvi Ponnikas, Hongkai Zhang, Max Lundberg, Lucile Soler, Ignas Bunikis, Maja Tarka, Dennis Hasselquist, Björn Nystedt, Helena Westerdahl, Bengt Hansson
Published in: Molecular Biology and Evolution, 2021, ISSN 0737-4038
Publisher: Oxford University Press
DOI: 10.1093/molbev/msab277

High MHC gene copy number maintains diversity despite homozygosity in a Critically Endangered single‐island endemic bird, but no evidence of MHC‐based mate choice

Author(s): Martin Stervander, Elisa G. Dierickx, Jack Thorley, M. de L. Brooke, Helena Westerdahl
Published in: Molecular Ecology, Issue 29/19, 2020, Page(s) 3578-3592, ISSN 0962-1083
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/mec.15471

Trade‐offs in expressed major histocompatibility complex diversity seen on a macroevolutionary scale among songbirds

Author(s): Emily A. O'Connor, Helena Westerdahl
Published in: Evolution, Issue 75/5, 2021, Page(s) 1061-1069, ISSN 0014-3820
Publisher: Society for the Study of Evolution
DOI: 10.1111/evo.14207

Avian MHC Evolution in the Era of Genomics: Phase 1.0

Author(s): Emily A. O’Connor, Helena Westerdahl, Reto Burri, Scott V. Edwards
Published in: Cells, Issue 8/10, 2019, Page(s) 1152, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells8101152

Wetter climates select for higher immune gene diversity in resident, but not migratory, songbirds

Author(s): Emily A. O'Connor, Dennis Hasselquist, Jan-Åke Nilsson, Helena Westerdahl, Charlie K. Cornwallis
Published in: Proceedings of the Royal Society B: Biological Sciences, Issue 287/1919, 2020, Page(s) 20192675, ISSN 0962-8452
Publisher: Royal Society of London
DOI: 10.1098/rspb.2019.2675

Whole‐genome sequencing and genome regions of special interest: Lessons from major histocompatibility complex, sex determination, and plant self‐incompatibility

Author(s): Xavier Vekemans, Vincent Castric, Helen Hipperson, Niels A. Müller, Helena Westerdahl, Quentin Cronk
Published in: Molecular Ecology, 2021, ISSN 0962-1083
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/mec.16020

Seasonal dynamics of haemosporidian (Apicomplexa, Haemosporida) parasites in house sparrows Passer domesticus at four European sites: comparison between lineages and the importance of screening methods

Author(s): Júlio Manuel Neto, Samantha Mellinger, Lucyna Halupka, Alfonso Marzal, Pavel Zehtindjiev, Helena Westerdahl
Published in: International Journal for Parasitology, Issue 50/6-7, 2020, Page(s) 523-532, ISSN 0020-7519
Publisher: Elsevier BV
DOI: 10.1016/j.ijpara.2020.03.008

Evidence for sexual conflict over major histocompatibility complex diversity in a wild songbird

Author(s): Jacob Roved, Bengt Hansson, Maja Tarka, Dennis Hasselquist, Helena Westerdahl
Published in: Proceedings of the Royal Society B: Biological Sciences, Issue 285/1884, 2018, Page(s) 20180841, ISSN 0962-8452
Publisher: Royal Society of London
DOI: 10.1098/rspb.2018.0841