Establishing genetic code expansion as a tool to study neuronal circuit function in an animal

Información del proyecto

UAAWORM

Identificador del acuerdo de subvención: 679990

DOI 10.3030/679990

Proyecto cerrado

Fecha de la firma de la CE 17 Marzo 2016

Fecha de inicio 1 Abril 2016

Fecha de finalización 30 Septiembre 2022

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total € 1 499 520,00

Aportación de la UE € 1 499 520,00

Coordinado por

THE UNIVERSITY OF EDINBURGH
United Kingdom

Publicaciones

Peer reviewed articles (3)

Using a quadruplet codon to expand the genetic code of an animal

Autores: Zhiyan Xi, Lloyd Davis, Kieran Baxter, Ailish Tynan, Angeliki Goutou, Sebastian Greiss
Publicado en: Nucleic Acids Research, 2021, ISSN 0305-1048
Editor: Oxford University Press
DOI: 10.1093/nar/gkab1168

Precise optical control of gene expression in C. elegans using improved genetic code expansion and Cre recombinase

Autores: Lloyd Davis, Inja Radman, Angeliki Goutou, Ailish Tynan, Kieran Baxter, Zhiyan Xi, Jack M O'Shea, Jason W Chin, Sebastian Greiss
Publicado en: eLife, Edición 10, 2021, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.67075

Generation of Photocaged Nanobodies for Intracellular Applications in an Animal Using Genetic Code Expansion and Computationally Guided Protein Engineering

Autores: Jack M. O'Shea, Angeliki Goutou, Jack Brydon, Cyrus R. Sethna, Christopher W. Wood, Sebastian Greiss
Publicado en: ChemBioChem, 2022, ISSN 1439-7633
Editor: Wiley-VCH GmbH
DOI: 10.1002/cbic.202200321

Other (3)

Using a Quadruplet Codon to Expand the Genetic Code of an Animal

Autores: Zhiyan Xi, Lloyd Davis, Kieran Baxter, Ailish Tynan, Angeliki Goutou, Sebastian Greiss
Publicado en: bioRxiv, 2021
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/2021.07.17.452788

Generation of photocaged nanobodies for in vivo applications using genetic code expansion and computationally guided protein engineering

Autores: Jack M. O’Shea, Angeliki Goutou, Cyrus Sethna, Christopher W. Wood, Sebastian Greiss
Publicado en: bioRxiv, 2021
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/2021.04.16.440193

Optically splitting symmetric neuron pairs in C. elegans

Autores: Lloyd Davis, Inja Radman, Angeliki Goutou, Ailish Tynan, Kieran Baxter, Zhiyan Xi, Jason W Chin, Sebastian Greiss
Publicado en: bioRxiv, 2020
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/2020.05.02.072363

Book chapters (1)

Genetic Encoding of Unnatural Amino Acids in C. elegans

Autores: Lloyd Davis, Sebastian Greiss
Publicado en: Noncanonical Amino Acids - Methods and Protocols, Edición 1728, 2018, Página(s) 389-408, ISBN 978-1-4939-7573-0
Editor: Springer New York
DOI: 10.1007/978-1-4939-7574-7_24