Periodic Reporting for period 1 - HisMoDetect (An Antibody Microarray for Histone Modifications)
Período documentado: 2015-10-01 hasta 2017-03-31
Currently a Western blot is required in order to determine the state of each of the dozens of different histone modifications. Because of the growing number of histone modifications, this procedure is time consuming and labour intensive. Here, we developed an antibody microarray to monitor the levels of all histone modifications simultaneously. This method is essentially useful for any tissue or cell type in any biological process, for diagnosis, prognosis and drug screening. In addition to basic research, our platform will enable fast and reliable screening for epigenetic effects of existing and novel drugs.
We are now in a licencing process of this technology, as legal contracts are being reviewed by our legal department for a potential agreement with Diagenode - a leading epigenetic company.