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Beyond CRISPR: Systematic characterization of novel anti-phage defense systems in the microbial pan-genome

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Publications

DISARM is a widespread bacterial defence system with broad anti-phage activities

Author(s): Gal Ofir, Sarah Melamed, Hila Sberro, Zohar Mukamel, Shahar Silverman, Gilad Yaakov, Shany Doron, Rotem Sorek
Published in: Nature Microbiology, Issue 3/1, 2018, Page(s) 90-98, ISSN 2058-5276
DOI: 10.1038/s41564-017-0051-0

Communication between viruses guides lysis–lysogeny decisions

Author(s): Zohar Erez, Ida Steinberger-Levy, Maya Shamir, Shany Doron, Avigail Stokar-Avihail, Yoav Peleg, Sarah Melamed, Azita Leavitt, Alon Savidor, Shira Albeck, Gil Amitai, Rotem Sorek
Published in: Nature, Issue 541/7638, 2017, Page(s) 488-493, ISSN 0028-0836
DOI: 10.1038/nature21049

Repeat Size Determination by Two Molecular Rulers in the Type I-E CRISPR Array

Author(s): Moran G. Goren, Shany Doron, Rea Globus, Gil Amitai, Rotem Sorek, Udi Qimron
Published in: Cell Reports, Issue 16/11, 2016, Page(s) 2811-2818, ISSN 2211-1247
DOI: 10.1016/j.celrep.2016.08.043

High-resolution RNA 3′-ends mapping of bacterial Rho-dependent transcripts

Author(s): Dar, Daniel; Sorek, Rotem
Published in: Nucleic Acids Research, Issue 1, 2018, ISSN 0305-1048
DOI: 10.1093/nar/gky274

HflXr, a homolog of a ribosome-splitting factor, mediates antibiotic resistance

Author(s): Mélodie Duval, Daniel Dar, Filipe Carvalho, Eduardo P. C. Rocha, Rotem Sorek, Pascale Cossart
Published in: Proceedings of the National Academy of Sciences, Issue 115/52, 2018, Page(s) 13359-13364, ISSN 0027-8424
DOI: 10.1073/pnas.1810555115

Extensive reshaping of bacterial operons by programmed mRNA decay

Author(s): Daniel Dar, Rotem Sorek
Published in: PLOS Genetics, Issue 14/4, 2018, Page(s) e1007354, ISSN 1553-7404
DOI: 10.1371/journal.pgen.1007354

Systematic discovery of antiphage defense systems in the microbial pangenome

Author(s): Shany Doron, Sarah Melamed, Gal Ofir, Azita Leavitt, Anna Lopatina, Mai Keren, Gil Amitai, Rotem Sorek
Published in: Science, Issue 359/6379, 2018, Page(s) eaar4120, ISSN 0036-8075
DOI: 10.1126/science.aar4120