RNAi-mediated Epigenetic Gene Regulation

Project Information

REpiReg

Grant agreement ID: 681213

DOI 10.3030/681213

Project closed

EC signature date 29 April 2016

Start date 1 January 2017

End date 30 June 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 998 557,00

EU contribution € 1 998 557,00

Coordinated by

FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION
Switzerland

Publications

Peer reviewed articles (6)

Small RNAs in the Transgenerational Inheritance of Epigenetic Information

Author(s): Lea Duempelmann, Merle Skribbe, Marc Bühler
Published in: Trends in Genetics, Issue 36/3, 2020, Page(s) 203-214, ISSN 0168-9525
Publisher: Elsevier BV
DOI: 10.1016/j.tig.2019.12.001

A fully automated deep learning pipeline for high-throughput colony segmentation and classification

Author(s): Sarah H. Carl, Lea Duempelmann, Yukiko Shimada, Marc Bühler
Published in: Biology Open, Issue 9/6, 2020, Page(s) bio052936, ISSN 2046-6390
Publisher: Biology Open
DOI: 10.1242/bio.052936

Differential phosphorylation of Clr4SUV39H by Cdk1accompanies a histone H3 methylation switch thatis essential for gametogenesis

Author(s): Tahsin Kuzdere, Valentin Flury, Thomas Schalch, Vytautas Iesmantavicius, Daniel Hess Marc B€uhler
Published in: EMBO reports, 2022, ISSN 1469-3178
Publisher: EMBO press
DOI: 10.15252/embr.202255928

Inheritance of a Phenotypically Neutral Epimutation Evokes Gene Silencing in Later Generations

Author(s): Lea Duempelmann, Fabio Mohn, Yukiko Shimada, Daniele Oberti, Aude Andriollo, Silke Lochs, Marc Bühler
Published in: Molecular Cell, Issue 74/3, 2019, Page(s) 534-541.e4, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2019.02.009

The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1

Author(s): Valentin Flury, Paula Raluca Georgescu, Vytautas Iesmantavicius, Yukiko Shimada, Tahsin Kuzdere, Sigurd Braun, Marc B?hler
Published in: Molecular Cell, 2017, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2017.05.026

An enhancer screen identifies new suppressors of small-RNA-mediated epigenetic gene silencing

Author(s): Yukiko Shimada, Sarah H. Carl, Merle Skribbe, Valentin Flury, Tahsin Kuzdere, Georg Kempf, Marc Bühler
Published in: PLOS Genetics, Issue 17/6, 2021, Page(s) e1009645, ISSN 1553-7404
Publisher: PLos Genetics
DOI: 10.1371/journal.pgen.1009645