Publications Peer reviewed articles (79) Serum neurofilament light protein predicts clinical outcome in traumatic brain injury Author(s): Pashtun Shahim, Magnus Gren, Victor Liman, Ulf Andreasson, Niklas Norgren, Yelverton Tegner, Niklas Mattsson, Niels Andreasen, Martin Öst, Henrik Zetterberg, Bengt Nellgård, Kaj Blennow Published in: Scientific Reports, Issue 6/1, 2016, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/srep36791 Serum neurofilament light as a biomarker for mild traumatic brain injury in contact sports Author(s): Pashtun Shahim, Henrik Zetterberg, Yelverton Tegner, Kaj Blennow Published in: Neurology, Issue 88/19, 2017, Page(s) 1788-1794, ISSN 0028-3878 Publisher: Lippincott Williams & Wilkins Ltd. DOI: 10.1212/WNL.0000000000003912 Apolipoprotein E genotypes and longevity across dementia disorders Author(s): Tobias Skillbäck, Ronald Lautner, Niklas Mattsson, Jonathan M. Schott, Katarina Nägga, Lena Kilander, Anders Wimo, Bengt Winblad, Maria Eriksdotter, Kaj Blennow, Henrik Zetterberg Published in: Alzheimer's & Dementia, 2018, ISSN 1552-5260 Publisher: Elsevier BV DOI: 10.1016/j.jalz.2018.02.003 Preclinical effects of APOE ε4 on cerebrospinal fluid Aβ42 concentrations Author(s): Ronald Lautner, Philip S. Insel, Tobias Skillbäck, Bob Olsson, Mikael Landén, Giovanni B. Frisoni, Sanna-Kaisa Herukka, Harald Hampel, Anders Wallin, Lennart Minthon, Oskar Hansson, Kaj Blennow, Niklas Mattsson, Henrik Zetterberg Published in: Alzheimer's Research & Therapy, Issue 9/1, 2017, ISSN 1758-9193 Publisher: BioMed Central DOI: 10.1186/s13195-017-0313-3 Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease Author(s): Niklas Mattsson, Colin Groot, Willemijn J. Jansen, Susan M. Landau, Victor L. Villemagne, Sebastiaan Engelborghs, Mark M. Mintun, Alberto Lleo, José Luis Molinuevo, William J. Jagust, Giovanni B. Frisoni, Adrian Ivanoiu, Gaël Chételat, Catarina Resende de Oliveira, Karen M. Rodrigue, Johannes Kornhuber, Anders Wallin, Aleksandra Klimkowicz-Mrowiec, Ramesh Kandimalla, Julius Popp, Pauline P. Aal Published in: Alzheimer's & Dementia, 2018, ISSN 1552-5260 Publisher: Elsevier BV DOI: 10.1016/j.jalz.2018.02.009 Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia Author(s): Willemijn J. Jansen, Rik Ossenkoppele, Betty M. Tijms, Anne M. Fagan, Oskar Hansson, William E. Klunk, Wiesje M. van der Flier, Victor L. Villemagne, Giovanni B. Frisoni, Adam S. Fleisher, Alberto Lleó, Mark A. Mintun, Anders Wallin, Sebastiaan Engelborghs, Duk L. Na, Gäel Chételat, José Luis Molinuevo, Susan M. Landau, Niklas Mattsson, Johannes Kornhuber, Osama Sabri, Christopher C. Rowe, Luc Published in: JAMA Psychiatry, Issue 75/1, 2018, Page(s) 84, ISSN 2168-622X Publisher: American Medical Association DOI: 10.1001/jamapsychiatry.2017.3391 Concordance Between Different Amyloid Immunoassays and Visual Amyloid Positron Emission Tomographic Assessment Author(s): Shorena Janelidze, Josef Pannee, Alvydas Mikulskis, Ping Chiao, Henrik Zetterberg, Kaj Blennow, Oskar Hansson Published in: JAMA Neurology, Issue 74/12, 2017, Page(s) 1492, ISSN 2168-6149 Publisher: American Medical Association DOI: 10.1001/jamaneurol.2017.2814 Earliest accumulation of β-amyloid occurs within the default-mode network and concurrently affects brain connectivity Author(s): Sebastian Palmqvist, Michael Schöll, Olof Strandberg, Niklas Mattsson, Erik Stomrud, Henrik Zetterberg, Kaj Blennow, Susan Landau, William Jagust, Oskar Hansson Published in: Nature Communications, Issue 8/1, 2017, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-017-01150-x A novel quantification-driven proteomic strategy identifies an endogenous peptide of pleiotrophin as a new biomarker of Alzheimer’s disease Author(s): Tobias Skillbäck, Niklas Mattsson, Karl Hansson, Ekaterina Mirgorodskaya, Rahil Dahlén, Wiesje van der Flier, Philip Scheltens, Floor Duits, Oskar Hansson, Charlotte Teunissen, Kaj Blennow, Henrik Zetterberg, Johan Gobom Published in: Scientific Reports, Issue 7/1, 2017, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/s41598-017-13831-0 CSF/serum albumin ratio in dementias: a cross-sectional study on 1861 patients Author(s): Tobias Skillbäck, Louise Delsing, Jane Synnergren, Niklas Mattsson, Shorena Janelidze, Katarina Nägga, Lena Kilander, Ryan Hicks, Anders Wimo, Bengt Winblad, Oskar Hansson, Kaj Blennow, Maria Eriksdotter, Henrik Zetterberg Published in: Neurobiology of Aging, Issue 59, 2017, Page(s) 1-9, ISSN 0197-4580 Publisher: Elsevier BV DOI: 10.1016/j.neurobiolaging.2017.06.028 Mass Spectrometric Analysis of Cerebrospinal Fluid Ubiquitin in Alzheimer's Disease and Parkinsonian Disorders Author(s): Simon Sjödin, Oskar Hansson, Annika Öhrfelt, Gunnar Brinkmalm, Henrik Zetterberg, Ann Brinkmalm, Kaj Blennow Published in: PROTEOMICS - Clinical Applications, Issue 11/11-12, 2017, Page(s) 1700100, ISSN 1862-8346 Publisher: Wiley - VCH Verlag GmbH & CO. KGaA DOI: 10.1002/prca.201700100 18 F‐AV‐1451 and CSF T‐tau and P‐tau as biomarkers in Alzheimer's disease Author(s): Niklas Mattsson, Michael Schöll, Olof Strandberg, Ruben Smith, Sebastian Palmqvist, Philip S Insel, Douglas Hägerström, Tomas Ohlsson, Henrik Zetterberg, Jonas Jögi, Kaj Blennow, Oskar Hansson Published in: EMBO Molecular Medicine, Issue 9/9, 2017, Page(s) 1212-1223, ISSN 1757-4676 Publisher: John Wiley & Sons Ltd. DOI: 10.15252/emmm.201707809 Increased blood-brain barrier permeability is associated with dementia and diabetes but not amyloid pathology or APOE genotype Author(s): Shorena Janelidze, Joakim Hertze, Katarina Nägga, Karin Nilsson, Christer Nilsson, Malin Wennström, Danielle van Westen, Kaj Blennow, Henrik Zetterberg, Oskar Hansson Published in: Neurobiology of Aging, Issue 51, 2017, Page(s) 104-112, ISSN 0197-4580 Publisher: Elsevier BV DOI: 10.1016/j.neurobiolaging.2016.11.017 The pre-synaptic vesicle protein synaptotagmin is a novel biomarker for Alzheimer’s disease Author(s): Annika Öhrfelt, Ann Brinkmalm, Julien Dumurgier, Gunnar Brinkmalm, Oskar Hansson, Henrik Zetterberg, Elodie Bouaziz-Amar, Jacques Hugon, Claire Paquet, Kaj Blennow Published in: Alzheimer's Research & Therapy, Issue 8/1, 2016, ISSN 1758-9193 Publisher: BioMed Central DOI: 10.1186/s13195-016-0208-8 Reference measurement procedure for CSF amyloid beta (Aβ) 1-42 and the CSF Aβ 1-42 /Aβ 1-40 ratio - a cross-validation study against amyloid PET Author(s): Josef Pannee, Erik Portelius, Lennart Minthon, Johan Gobom, Ulf Andreasson, Henrik Zetterberg, Oskar Hansson, Kaj Blennow Published in: Journal of Neurochemistry, Issue 139/4, 2016, Page(s) 651-658, ISSN 0022-3042 Publisher: Blackwell Publishing Inc. DOI: 10.1111/jnc.13838 Low-dose γ-secretase inhibition increases secretion of Aβ peptides and intracellular oligomeric Aβ Author(s): Lotta Agholme, Marcus Clarin, Eleni Gkanatsiou, Petronella Kettunen, Jasmine Chebli, Gunnar Brinkmalm, Kaj Blennow, Petra Bergström, Erik Portelius, Henrik Zetterberg Published in: Molecular and Cellular Neuroscience, Issue 85, 2017, Page(s) 211-219, ISSN 1044-7431 Publisher: Academic Press DOI: 10.1016/j.mcn.2017.10.009 Cerebrospinal fluid β-amyloid 42 and neurofilament light relate to white matter hyperintensities Author(s): Katie E. Osborn, Dandan Liu, Lauren R. Samuels, Elizabeth E. Moore, Francis E. Cambronero, Lealani Mae Y. Acosta, Susan P. Bell, Michelle A. Babicz, Elizabeth A. Gordon, Kimberly R. Pechman, L. Taylor Davis, Katherine A. Gifford, Timothy J. Hohman, Kaj Blennow, Henrik Zetterberg, Angela L. Jefferson Published in: Neurobiology of Aging, Issue 68, 2018, Page(s) 18-25, ISSN 0197-4580 Publisher: Elsevier BV DOI: 10.1016/j.neurobiolaging.2018.03.028 Molecular biomarkers of Alzheimer's disease: progress and prospects Author(s): Tammaryn Lashley, Jonathan M. Schott, Philip Weston, Christina E. Murray, Henny Wellington, Ashvini Keshavan, Sandrine C. Foti, Martha Foiani, Jamie Toombs, Jonathan D. Rohrer, Amanda Heslegrave, Henrik Zetterberg Published in: Disease Models & Mechanisms, Issue 11/5, 2018, Page(s) dmm031781, ISSN 1754-8403 Publisher: The Company of Biologists Ltd. DOI: 10.1242/dmm.031781 Inhibiting the Ca 2+ Influx Induced by Human CSF Author(s): Anna Drews, Suman De, Patrick Flagmeier, David C. Wirthensohn, Wei-Hsin Chen, Daniel R. Whiten, Margarida Rodrigues, Cécile Vincke, Serge Muyldermans, Ross W. Paterson, Catherine F. Slattery, Nick C. Fox, Jonathan M. Schott, Henrik Zetterberg, Christopher M. Dobson, Sonia Gandhi, David Klenerman Published in: Cell Reports, Issue 21/11, 2017, Page(s) 3310-3316, ISSN 2211-1247 Publisher: Cell Press DOI: 10.1016/j.celrep.2017.11.057 The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics Author(s): Isabelle Bos, Stephanie Vos, Rik Vandenberghe, Philip Scheltens, Sebastiaan Engelborghs, Giovanni Frisoni, José Luis Molinuevo, Anders Wallin, Alberto Lleó, Julius Popp, Pablo Martinez-Lage, Alison Baird, Richard Dobson, Cristina Legido-Quigley, Kristel Sleegers, Christine Van Broeckhoven, Lars Bertram, Mara ten Kate, Frederik Barkhof, Henrik Zetterberg, Simon Lovestone, Johannes Streffer, Piete Published in: Alzheimer's Research & Therapy, Issue 10/1, 2018, ISSN 1758-9193 Publisher: BioMed Central DOI: 10.1186/s13195-018-0396-5 Multimodal Chemical Imaging of Amyloid Plaque Polymorphism Reveals Aβ Aggregation Dependent Anionic Lipid Accumulations and Metabolism Author(s): Wojciech Michno, Ibrahim Kaya, Sofie Nyström, Laurent Guerard, K. Peter R. Nilsson, Per Hammarström, Kaj Blennow, Henrik Zetterberg, Jörg Hanrieder Published in: Analytical Chemistry, Issue 90/13, 2018, Page(s) 8130-8138, ISSN 0003-2700 Publisher: American Chemical Society DOI: 10.1021/acs.analchem.8b01361 Shedding Light on the Molecular Pathology of Amyloid Plaques in Transgenic Alzheimer’s Disease Mice Using Multimodal MALDI Imaging Mass Spectrometry Author(s): Ibrahim Kaya, Henrik Zetterberg, Kaj Blennow, Jörg Hanrieder Published in: ACS Chemical Neuroscience, 2018, ISSN 1948-7193 Publisher: American Chemical Society DOI: 10.1021/acschemneuro.8b00121 Novel Trimodal MALDI Imaging Mass Spectrometry (IMS3) at 10 μm Reveals Spatial Lipid and Peptide Correlates Implicated in Aβ Plaque Pathology in Alzheimer’s Disease Author(s): Ibrahim Kaya, Dimitri Brinet, Wojciech Michno, Mehmet Başkurt, Henrik Zetterberg, Kaj Blenow, Jörg Hanrieder Published in: ACS Chemical Neuroscience, Issue 8/12, 2017, Page(s) 2778-2790, ISSN 1948-7193 Publisher: American Chemical Society DOI: 10.1021/acschemneuro.7b00314 Delineating Amyloid Plaque Associated Neuronal Sphingolipids in Transgenic Alzheimer’s Disease Mice (tgArcSwe) Using MALDI Imaging Mass Spectrometry Author(s): Ibrahim Kaya, Dimitri Brinet, Wojciech Michno, Stina Syvänen, Dag Sehlin, Henrik Zetterberg, Kaj Blennow, Jörg Hanrieder Published in: ACS Chemical Neuroscience, Issue 8/2, 2016, Page(s) 347-355, ISSN 1948-7193 Publisher: American Chemical Society DOI: 10.1021/acschemneuro.6b00391 Histology-Compatible MALDI Mass Spectrometry Based Imaging of Neuronal Lipids for Subsequent Immunofluorescent Staining Author(s): Ibrahim Kaya, Wojciech Michno, Dimitri Brinet, Yasmine Iacone, Giulia Zanni, Kaj Blennow, Henrik Zetterberg, Jörg Hanrieder Published in: Analytical Chemistry, Issue 89/8, 2017, Page(s) 4685-4694, ISSN 0003-2700 Publisher: American Chemical Society DOI: 10.1021/acs.analchem.7b00313 Sleep deprivation and cerebrospinal fluid biomarkers for Alzheimer’s disease Author(s): Martin Olsson, Johan Ärlig, Jan Hedner, Kaj Blennow, Henrik Zetterberg Published in: Sleep, Issue 41/5, 2018, ISSN 0161-8105 Publisher: The American Academy of Sleep Medicine DOI: 10.1093/sleep/zsy025 Synaptic proteins in CSF as potential novel biomarkers for prognosis in prodromal Alzheimer’s disease Author(s): Flora H. Duits, Gunnar Brinkmalm, Charlotte E. Teunissen, Ann Brinkmalm, Philip Scheltens, Wiesje M. Van der Flier, Henrik Zetterberg, Kaj Blennow Published in: Alzheimer's Research & Therapy, Issue 10/1, 2018, ISSN 1758-9193 Publisher: BioMed Central DOI: 10.1186/s13195-017-0335-x Sulfatide isoform pattern in cerebrospinal fluid discriminates progressive MS from relapsing-remitting MS Author(s): Lenka Novakova, Avadhesh Kumar Singh, Markus Axelsson, Marcus Ståhlman, Martin Adiels, Clas Malmeström, Henrik Zetterberg, Jan Borén, Jan Lycke, Susanna L. Cardell, Maria Blomqvist Published in: Journal of Neurochemistry, 2018, ISSN 0022-3042 Publisher: Blackwell Publishing Inc. DOI: 10.1111/jnc.14452 Evolution of cerebrospinal fluid total α-synuclein in Parkinson's disease Author(s): Marthe Gurine Førland, Annika Öhrfelt, Ingvild Dalen, Ole-Bjørn Tysnes, Kaj Blennow, Henrik Zetterberg, Kenn Freddy Pedersen, Guido Alves, Johannes Lange Published in: Parkinsonism & Related Disorders, Issue 49, 2018, Page(s) 4-8, ISSN 1353-8020 Publisher: Elsevier BV DOI: 10.1016/j.parkreldis.2018.01.018 Neurofilament light as a blood biomarker for neurodegeneration in Down syndrome Author(s): Andre Strydom, Amanda Heslegrave, Carla M. Startin, Kin Y. Mok, John Hardy, Jurgen Groet, Dean Nizetic, Henrik Zetterberg Published in: Alzheimer's Research & Therapy, Issue 10/1, 2018, ISSN 1758-9193 Publisher: BioMed Central DOI: 10.1186/s13195-018-0367-x Serum neurofilament light chain in progressive supranuclear palsy Author(s): Laura Donker Kaat, Lieke H. Meeter, Wan Zheng Chiu, Shami Melhem, Agnita J.W. Boon, Kaj Blennow, Henrik Zetterberg, John C. van Swieten Published in: Parkinsonism & Related Disorders, 2018, ISSN 1353-8020 Publisher: Elsevier BV DOI: 10.1016/j.parkreldis.2018.06.018 Neuromodulation via the Cerebrospinal Fluid: Insights from Recent in Vitro Studies Author(s): Andreas Bjorefeldt, Sebastian Illes, Henrik Zetterberg, Eric Hanse Published in: Frontiers in Neural Circuits, Issue 12, 2018, ISSN 1662-5110 Publisher: Frontiers Research Foundation DOI: 10.3389/fncir.2018.00005 Moderate intensity physical activity associates with CSF biomarkers in a cohort at risk for Alzheimer's disease Author(s): Lena L. Law, Rachael N. Rol, Stephanie A. Schultz, Ryan J. Dougherty, Dorothy F. Edwards, Rebecca L. Koscik, Catherine L. Gallagher, Cynthia M. Carlsson, Barbara B. Bendlin, Henrik Zetterberg, Kaj Blennow, Sanjay Asthana, Mark A. Sager, Bruce P. Hermann, Sterling C. Johnson, Dane B. Cook, Ozioma C. Okonkwo Published in: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Issue 10, 2018, Page(s) 188-195, ISSN 2352-8729 Publisher: Alzheimer's Association DOI: 10.1016/j.dadm.2018.01.001 Plasma and cerebrospinal fluid tau and neurofilament concentrations in rapidly progressive neurological syndromes: a neuropathology-based cohort Author(s): G. G. Kovacs, U. Andreasson, V. Liman, G. Regelsberger, M. I. Lutz, K. Danics, E. Keller, H. Zetterberg, K. Blennow Published in: European Journal of Neurology, Issue 24/11, 2017, Page(s) 1326-e77, ISSN 1351-5101 Publisher: Blackwell Publishing Inc. DOI: 10.1111/ene.13389 Association of Changes in Plasma Neurofilament Light and Tau Levels With Anesthesia and Surgery Author(s): Lisbeth Evered, Brendan Silbert, David A. Scott, Henrik Zetterberg, Kaj Blennow Published in: JAMA Neurology, Issue 75/5, 2018, Page(s) 542, ISSN 2168-6149 Publisher: American Medical Association DOI: 10.1001/jamaneurol.2017.4913 The use of cerebrospinal fluid biomarkers to measure change in neurodegeneration in Alzheimer’s disease clinical trials Author(s): Bob Olsson, Jonathan M. Schott, Kaj Blennow, Henrik Zetterberg Published in: Expert Review of Neurotherapeutics, Issue 17/8, 2017, Page(s) 767-775, ISSN 1473-7175 Publisher: Future Drugs Ltd. DOI: 10.1080/14737175.2017.1341311 Blood-based cerebral biomarkers in preeclampsia: Plasma concentrations of NfL, tau, S100B and NSE during pregnancy in women who later develop preeclampsia - A nested case control study Author(s): Lina Bergman, Henrik Zetterberg, Helena Kaihola, Henrik Hagberg, Kaj Blennow, Helena Åkerud Published in: PLOS ONE, Issue 13/5, 2018, Page(s) e0196025, ISSN 1932-6203 Publisher: Public Library of Science DOI: 10.1371/journal.pone.0196025 Serum Neurofilament Light Protein as a Marker for Diffuse Axonal Injury: Results from a Case Series Study Author(s): Johan Ljungqvist, Henrik Zetterberg, Marios Mitsis, Kaj Blennow, Thomas Skoglund Published in: Journal of Neurotrauma, Issue 34/5, 2017, Page(s) 1124-1127, ISSN 0897-7151 Publisher: Mary Ann Liebert Inc. DOI: 10.1089/neu.2016.4496 Fluid biomarkers for mild traumatic brain injury and related conditions Author(s): Henrik Zetterberg, Kaj Blennow Published in: Nature Reviews Neurology, Issue 12/10, 2016, Page(s) 563-574, ISSN 1759-4758 Publisher: Nature Publishing Group DOI: 10.1038/nrneurol.2016.127 Neurofilament light protein levels in cerebrospinal fluid predict long-term disability of Guillain-Barré syndrome: A pilot study Author(s): M. Axelsson, M. Sjögren, O. Andersen, K. Blennow, H. Zetterberg, J. Lycke Published in: Acta Neurologica Scandinavica, Issue 138/2, 2018, Page(s) 143-150, ISSN 0001-6314 Publisher: Blackwell Publishing Inc. DOI: 10.1111/ane.12927 Proteomic studies of cerebrospinal fluid biomarkers of Alzheimer’s disease: an update Author(s): Erik Portelius, Gunnar Brinkmalm, Josef Pannee, Henrik Zetterberg, Kaj Blennow, Rahil Dahlén, Ann Brinkmalm, Johan Gobom Published in: Expert Review of Proteomics, Issue 14/11, 2017, Page(s) 1007-1020, ISSN 1478-9450 Publisher: Future Drugs Ltd. DOI: 10.1080/14789450.2017.1384697 Applying fluid biomarkers to Alzheimer's disease Author(s): Henrik Zetterberg Published in: American Journal of Physiology-Cell Physiology, Issue 313/1, 2017, Page(s) C3-C10, ISSN 0363-6143 Publisher: American Physiological Society DOI: 10.1152/ajpcell.00007.2017 High Interferon-γ Uniquely in Vδ1 T Cells Correlates with Markers of Inflammation and Axonal Damage in Early Multiple Sclerosis Author(s): Avadhesh Kumar Singh, Lenka Novakova, Markus Axelsson, Clas Malmeström, Henrik Zetterberg, Jan Lycke, Susanna L. Cardell Published in: Frontiers in Immunology, Issue 8, 2017, ISSN 1664-3224 Publisher: Frontiers DOI: 10.3389/fimmu.2017.00260 Review: Tau in biofluids - relation to pathology, imaging and clinical features Author(s): H. Zetterberg Published in: Neuropathology and Applied Neurobiology, Issue 43/3, 2017, Page(s) 194-199, ISSN 0305-1846 Publisher: Blackwell Publishing Inc. DOI: 10.1111/nan.12378 Cerebrospinal fluid interferon alpha levels correlate with neurocognitive impairment in ambulatory HIV-Infected individuals Author(s): Albert M. Anderson, Jeffrey L. Lennox, Mark M. Mulligan, David W. Loring, Henrik Zetterberg, Kaj Blennow, Cari Kessing, Rajeth Koneru, Kirk Easley, William R. Tyor Published in: Journal of NeuroVirology, Issue 23/1, 2017, Page(s) 106-112, ISSN 1355-0284 Publisher: Springer Verlag DOI: 10.1007/s13365-016-0466-z Neurofilament light protein in blood predicts regional atrophy in Huntington disease Author(s): Eileanoir B. Johnson, Lauren M. Byrne, Sarah Gregory, Filipe B. Rodrigues, Kaj Blennow, Alexandra Durr, Blair R. Leavitt, Raymund A. Roos, Henrik Zetterberg, Sarah J. Tabrizi, Rachael I. Scahill, Edward J. Wild Published in: Neurology, Issue 90/8, 2018, Page(s) e717-e723, ISSN 0028-3878 Publisher: Lippincott Williams & Wilkins Ltd. DOI: 10.1212/WNL.0000000000005005 Neurofilament light protein in blood as a potential biomarker of neurodegeneration in Huntington's disease: a retrospective cohort analysis Author(s): Lauren M Byrne, Filipe B Rodrigues, Kaj Blennow, Alexandra Durr, Blair R Leavitt, Raymund A C Roos, Rachael I Scahill, Sarah J Tabrizi, Henrik Zetterberg, Douglas Langbehn, Edward J Wild Published in: The Lancet Neurology, Issue 16/8, 2017, Page(s) 601-609, ISSN 1474-4422 Publisher: The Lancet Publishing Group DOI: 10.1016/S1474-4422(17)30124-2 Cerebrospinal Fluid Inflammatory Biomarkers Reflect Clinical Severity in Huntington’s Disease Author(s): Filipe Brogueira Rodrigues, Lauren M. Byrne, Peter McColgan, Nicola Robertson, Sarah J. Tabrizi, Henrik Zetterberg, Edward J. Wild Published in: PLOS ONE, Issue 11/9, 2016, Page(s) e0163479, ISSN 1932-6203 Publisher: Public Library of Science DOI: 10.1371/journal.pone.0163479 Cerebrospinal fluid total tau concentration predicts clinical phenotype in Huntington's disease Author(s): Filipe Brogueira Rodrigues, Lauren Byrne, Peter McColgan, Nicola Robertson, Sarah J. Tabrizi, Blair R. Leavitt, Henrik Zetterberg, Edward J. Wild Published in: Journal of Neurochemistry, Issue 139/1, 2016, Page(s) 22-25, ISSN 0022-3042 Publisher: Blackwell Publishing Inc. DOI: 10.1111/jnc.13719 Amyloid precursor protein expression and processing are differentially regulated during cortical neuron differentiation Author(s): Petra Bergström, Lotta Agholme, Faisal Hayat Nazir, Tugce Munise Satir, Jamie Toombs, Henrietta Wellington, Joakim Strandberg, Thomas Olsson Bontell, Hlin Kvartsberg, Maria Holmström, Cecilia Boreström, Stina Simonsson, Tilo Kunath, Anders Lindahl, Kaj Blennow, Eric Hanse, Erik Portelius, Selina Wray, Henrik Zetterberg Published in: Scientific Reports, Issue 6/1, 2016, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/srep29200 Neuroinflammation and Tau Interact with Amyloid in Predicting Sleep Problems in Aging Independently of Atrophy Author(s): Anders Martin Fjell, Ane-Victoria Idland, Roser Sala-Llonch, Leiv Otto Watne, Tom Borza, Anne Brækhus, Tarjei Lona, Henrik Zetterberg, Kaj Blennow, Torgeir Bruun Wyller, Kristine Beate Walhovd Published in: Cerebral Cortex, 2017, Page(s) 1-11, ISSN 1047-3211 Publisher: Oxford University Press DOI: 10.1093/cercor/bhx157 Effects of surgery and propofol-remifentanil total intravenous anesthesia on cerebrospinal fluid biomarkers of inflammation, Alzheimer’s disease, and neuronal injury in humans: a cohort study Author(s): Andreas Pikwer, Markus Castegren, Sijal Namdar, Kaj Blennow, Henrik Zetterberg, Niklas Mattsson Published in: Journal of Neuroinflammation, Issue 14/1, 2017, ISSN 1742-2094 Publisher: BioMed Central DOI: 10.1186/s12974-017-0950-2 Alzheimer's disease markers in the aged sheep ( Ovis aries ) Author(s): Suzanne J. Reid, Natasha E. Mckean, Kristen Henty, Erik Portelius, Kaj Blennow, Skye R. Rudiger, C. Simon Bawden, Renee R. Handley, Paul J. Verma, Richard L.M. Faull, Henry J. Waldvogel, Henrik Zetterberg, Russell G. Snell Published in: Neurobiology of Aging, Issue 58, 2017, Page(s) 112-119, ISSN 0197-4580 Publisher: Elsevier BV DOI: 10.1016/j.neurobiolaging.2017.06.020 Amyloid mis-metabolism in idiopathic normal pressure hydrocephalus Author(s): A. Jeppsson, Mikko Höltta, H. Zetterberg, K. Blennow, C. Wikkelsø, Mats Tullberg Published in: Fluids and Barriers of the CNS, Issue 13/1, 2016, ISSN 2045-8118 Publisher: BioMed Central DOI: 10.1186/s12987-016-0037-y Update on ultrasensitive technologies to facilitate research on blood biomarkers for central nervous system disorders Author(s): Ulf Andreasson, Kaj Blennow, Henrik Zetterberg Published in: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Issue 3, 2016, Page(s) 98-102, ISSN 2352-8729 Publisher: Alzheimer´s Association DOI: 10.1016/j.dadm.2016.05.005 Neurofilament light in CSF and serum is a sensitive marker for axonal white matter injury in MS Author(s): Joakim Bergman, Ann Dring, Henrik Zetterberg, Kaj Blennow, Niklas Norgren, Jonathan Gilthorpe, Tommy Bergenheim, Anders Svenningsson Published in: Neurology - Neuroimmunology Neuroinflammation, Issue 3/5, 2016, Page(s) e271, ISSN 2332-7812 Publisher: American Academy of Neurology DOI: 10.1212/NXI.0000000000000271 Identification of candidate cerebrospinal fluid biomarkers in parkinsonism using quantitative proteomics Author(s): N.K. Magdalinou, A.J. Noyce, R. Pinto, E. Lindstrom, J. Holmén-Larsson, M. Holtta, K. Blennow, H.R. Morris, T. Skillbäck, T.T. Warner, A.J. Lees, I. Pike, M. Ward, H. Zetterberg, J. Gobom Published in: Parkinsonism & Related Disorders, Issue 37, 2017, Page(s) 65-71, ISSN 1353-8020 Publisher: Elsevier BV DOI: 10.1016/j.parkreldis.2017.01.016 CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis Author(s): Bob Olsson, Ronald Lautner, Ulf Andreasson, Annika Öhrfelt, Erik Portelius, Maria Bjerke, Mikko Hölttä, Christoffer Rosén, Caroline Olsson, Gabrielle Strobel, Elizabeth Wu, Kelly Dakin, Max Petzold, Kaj Blennow, Henrik Zetterberg Published in: The Lancet Neurology, Issue 15/7, 2016, Page(s) 673-684, ISSN 1474-4422 Publisher: The Lancet Publishing Group DOI: 10.1016/S1474-4422(16)00070-3 Reduced cerebrospinal fluid concentration of interleukin-12/23 subunit p40 in patients with cognitive impairment Author(s): Per Johansson, Erik G. Almqvist, Anders Wallin, Jan-Ove Johansson, Ulf Andreasson, Kaj Blennow, Henrik Zetterberg, Johan Svensson Published in: PLOS ONE, Issue 12/5, 2017, Page(s) e0176760, ISSN 1932-6203 Publisher: Public Library of Science DOI: 10.1371/journal.pone.0176760 Beneficial effects of increased lysozyme levels in Alzheimer's disease modelled in Drosophila melanogaster Author(s): Linnea Sandin, Liza Bergkvist, Sangeeta Nath, Claudia Kielkopf, Camilla Janefjord, Linda Helmfors, Henrik Zetterberg, Kaj Blennow, Hongyun Li, Camilla Nilsberth, Brett Garner, Ann-Christin Brorsson, Katarina Kågedal Published in: The FEBS Journal, Issue 283/19, 2016, Page(s) 3508-3522, ISSN 1742-464X Publisher: Blackwell Publishing Inc. DOI: 10.1111/febs.13830 Neurofilaments in blood and CSF for diagnosis and prediction of onset in Creutzfeldt-Jakob disease Author(s): Petra Steinacker, Kaj Blennow, Steffen Halbgebauer, Song Shi, Viktoria Ruf, Patrick Oeckl, Armin Giese, Jens Kuhle, Dana Slivarichova, Henrik Zetterberg, Markus Otto Published in: Scientific Reports, Issue 6/1, 2016, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/srep38737 Familial Alzheimer’s disease patient-derived neurons reveal distinct mutation-specific effects on amyloid beta Author(s): Charles Arber, Jamie Toombs, Christopher Lovejoy, Natalie S. Ryan, Ross W. Paterson, Nanet Willumsen, Eleni Gkanatsiou, Erik Portelius, Kaj Blennow, Amanda Heslegrave, Jonathan M. Schott, John Hardy, Tammaryn Lashley, Nick C. Fox, Henrik Zetterberg, Selina Wray Published in: Molecular Psychiatry, 2019, ISSN 1359-4184 Publisher: Nature Publishing Group DOI: 10.1038/s41380-019-0410-8 Neurofilament light and tau as blood biomarkers for sports-related concussion Author(s): Pashtun Shahim, Yelverton Tegner, Niklas Marklund, Kaj Blennow, Henrik Zetterberg Published in: Neurology, Issue 90/20, 2018, Page(s) e1780-e1788, ISSN 0028-3878 Publisher: Lippincott Williams & Wilkins Ltd. DOI: 10.1212/wnl.0000000000005518 Pittsburgh compound B imaging and cerebrospinal fluid amyloid-β in a multicentre European memory clinic study Author(s): Antoine Leuzy, Konstantinos Chiotis, Steen G. Hasselbalch, Juha O. Rinne, Alexandre de Mendonça, Markus Otto, Alberto Lleó, Miguel Castelo-Branco, Isabel Santana, Jarkko Johansson, Sarah Anderl-Straub, Christine A. F. von Arnim, Ambros Beer, Rafael Blesa, Juan Fortea, Sanna-Kaisa Herukka, Erik Portelius, Josef Pannee, Henrik Zetterberg, Kaj Blennow, Agneta Nordberg Published in: Brain, Issue 139/9, 2016, Page(s) 2540-2553, ISSN 0006-8950 Publisher: Oxford University Press DOI: 10.1093/brain/aww160 Plasma neurofilament light chain concentration in the inherited peripheral neuropathies Author(s): Åsa Sandelius, Henrik Zetterberg, Kaj Blennow, Rocco Adiutori, Andrea Malaspina, Matilde Laura, Mary M. Reilly, Alexander M. Rossor Published in: Neurology, Issue 90/6, 2018, Page(s) e518-e524, ISSN 0028-3878 Publisher: Lippincott Williams & Wilkins Ltd. DOI: 10.1212/wnl.0000000000004932 Blood-based NfL Author(s): Oskar Hansson, Shorena Janelidze, Sara Hall, Nadia Magdalinou, Andrew J. Lees, Ulf Andreasson, Niklas Norgren, Jan Linder, Lars Forsgren, Radu Constantinescu, Henrik Zetterberg, Kaj Blennow Published in: Neurology, Issue 88/10, 2017, Page(s) 930-937, ISSN 0028-3878 Publisher: Lippincott Williams & Wilkins Ltd. DOI: 10.1212/wnl.0000000000003680 Extrinsic Amyloid-Binding Dyes for Detection of Individual Protein Aggregates in Solution Author(s): Christopher G. Taylor, Georg Meisl, Mathew H. Horrocks, Henrik Zetterberg, Tuomas P. J. Knowles, David Klenerman Published in: Analytical Chemistry, Issue 90/17, 2018, Page(s) 10385-10393, ISSN 0003-2700 Publisher: American Chemical Society DOI: 10.1021/acs.analchem.8b02226 Obstructive Sleep Apnea Severity Affects Amyloid Burden in Cognitively Normal Elderly. A Longitudinal Study Author(s): Ram A. Sharma, Andrew W. Varga, Omonigho M. Bubu, Elizabeth Pirraglia, Korey Kam, Ankit Parekh, Margaret Wohlleber, Margo D. Miller, Andreia Andrade, Clifton Lewis, Samuel Tweardy, Maja Buj, Po L. Yau, Reem Sadda, Lisa Mosconi, Yi Li, Tracy Butler, Lidia Glodzik, Els Fieremans, James S. Babb, Kaj Blennow, Henrik Zetterberg, Shou E. Lu, Sandra G. Badia, Sergio Romero, Ivana Rosenzweig, Nadia Gossel Published in: American Journal of Respiratory and Critical Care Medicine, Issue 197/7, 2018, Page(s) 933-943, ISSN 1073-449X Publisher: American Thoracic Society DOI: 10.1164/rccm.201704-0704oc The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer’s disease Author(s): Nicholas M. Vogt, Kymberleigh A. Romano, Burcu F. Darst, Corinne D. Engelman, Sterling C. Johnson, Cynthia M. Carlsson, Sanjay Asthana, Kaj Blennow, Henrik Zetterberg, Barbara B. Bendlin, Federico E. Rey Published in: Alzheimer's Research & Therapy, Issue 10/1, 2018, ISSN 1758-9193 Publisher: BioMed Central DOI: 10.1186/s13195-018-0451-2 Comparing 18 F-AV-1451 with CSF t-tau and p-tau for diagnosis of Alzheimer disease Author(s): Niklas Mattsson, Ruben Smith, Olof Strandberg, Sebastian Palmqvist, Michael Schöll, Philip S. Insel, Douglas Hägerström, Tomas Ohlsson, Henrik Zetterberg, Kaj Blennow, Jonas Jögi, Oskar Hansson Published in: Neurology, Issue 90/5, 2018, Page(s) e388-e395, ISSN 0028-3878 Publisher: Lippincott Williams & Wilkins Ltd. DOI: 10.1212/wnl.0000000000004887 Increased midlife triglycerides predict brain β-amyloid and tau pathology 20 years later Author(s): Katarina Nägga, Anna-Märta Gustavsson, Erik Stomrud, Daniel Lindqvist, Danielle van Westen, Kaj Blennow, Henrik Zetterberg, Olle Melander, Oskar Hansson Published in: Neurology, Issue 90/1, 2017, Page(s) e73-e81, ISSN 0028-3878 Publisher: Lippincott Williams & Wilkins Ltd. DOI: 10.1212/wnl.0000000000004749 Serum neurofilament light in familial Alzheimer disease Author(s): Philip S.J. Weston, Teresa Poole, Natalie S. Ryan, Akshay Nair, Yuying Liang, Kirsty Macpherson, Ronald Druyeh, Ian B. Malone, R. Laila Ahsan, Hugh Pemberton, Jana Klimova, Simon Mead, Kaj Blennow, Martin N. Rossor, Jonathan M. Schott, Henrik Zetterberg, Nick C. Fox Published in: Neurology, Issue 89/21, 2017, Page(s) 2167-2175, ISSN 0028-3878 Publisher: Lippincott Williams & Wilkins Ltd. DOI: 10.1212/wnl.0000000000004667 Phenotypic Screening Identifies Modulators of Amyloid Precursor Protein Processing in Human Stem Cell Models of Alzheimer’s Disease Author(s): Brownjohn, Philip W.; Smith, James; Portelius, Erik; Serneels, Lutgarde; Kvartsberg, Hlin; De Strooper, Bart; Blennow, Kaj; Zetterberg, Henrik; Livesey, Frederick J. Published in: Stem Cell Reports, Issue 4, 2017, Page(s) 870-882, ISSN 2213-6711 Publisher: Cell Press DOI: 10.17863/CAM.9285 The nonlinear relationship between cerebrospinal fluid Aβ42 and tau in preclinical Alzheimer’s disease Author(s): Mony J. de Leon, Elizabeth Pirraglia, Ricardo S. Osorio, Lidia Glodzik, Les Saint-Louis, Hee-Jin Kim, Juan Fortea, Silvia Fossati, Eugene Laska, Carole Siegel, Tracy Butler, Yi Li, Henry Rusinek, Henrik Zetterberg, Kaj Blennow Published in: PLOS ONE, Issue 13/2, 2018, Page(s) e0191240, ISSN 1932-6203 Publisher: Public Library of Science DOI: 10.1371/journal.pone.0191240 Neurodegeneration, synaptic dysfunction, and gliosis are phenotypic of Alzheimer dementia Author(s): Andrew P. Merluzzi, Cynthia M. Carlsson, Sterling C. Johnson, Suzanne E. Schindler, Sanjay Asthana, Kaj Blennow, Henrik Zetterberg, Barbara B. Bendlin Published in: Neurology, Issue 91/5, 2018, Page(s) e436-e443, ISSN 0028-3878 Publisher: Lippincott Williams & Wilkins Ltd. DOI: 10.1212/wnl.0000000000005901 Astroglial activation and altered amyloid metabolism in human repetitive concussion Author(s): Pashtun Shahim, Yelverton Tegner, Niklas Marklund, Kina Höglund, Erik Portelius, David L. Brody, Kaj Blennow, Henrik Zetterberg Published in: Neurology, Issue 88/15, 2017, Page(s) 1400-1407, ISSN 0028-3878 Publisher: Lippincott Williams & Wilkins Ltd. DOI: 10.1212/wnl.0000000000003816 Association of IL1RAP-related genetic variation with cerebrospinal fluid concentration of Alzheimer-associated tau protein Author(s): Anna Zettergren, Kina Höglund, Silke Kern, Valgeir Thorvaldsson, Msc Johan Skoog, Oskar Hansson, Niels Andreasen, Nenad Bogdanovic, Kaj Blennow, Ingmar Skoog, Henrik Zetterberg Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/s41598-018-36650-3 Reduced Cerebrospinal Fluid Concentration of Apolipoprotein A-I in Patients with Alzheimer’s Disease Author(s): Per Johansson, Erik G. Almqvist, Maria Bjerke, Anders Wallin, Jan-Ove Johansson, Ulf Andreasson, Kaj Blennow, Henrik Zetterberg, Johan Svensson Published in: Journal of Alzheimer's Disease, Issue 59/3, 2017, Page(s) 1017-1026, ISSN 1387-2877 Publisher: IOS Press DOI: 10.3233/jad-170226 Soluble CD14 in cerebrospinal fluid is associated with markers of inflammation and axonal damage in untreated HIV-infected patients: a retrospective cross-sectional study Author(s): Sofie Jespersen, Karin Kæreby Pedersen, Birgitta Anesten, Henrik Zetterberg, Dietmar Fuchs, Magnus Gisslén, Lars Hagberg, Marius Trøseid, Susanne Dam Nielsen Published in: BMC Infectious Diseases, Issue 16/1, 2016, ISSN 1471-2334 Publisher: BioMed Central DOI: 10.1186/s12879-016-1510-6 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
