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Novel Approach to Systematically Characterize Exercise- and Nutrient- responsive genes in Type 2 diabetes and cardiovascular disease

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Publications

Established BMI-associated genetic variants and their prospective associations with BMI and other cardiometabolic traits: the GLACIER Study

Author(s): S Ahmad, A Poveda, D Shungin, I Barroso, G Hallmans, F Renström, P W Franks
Published in: International Journal of Obesity, Issue 40/9, 2016, Page(s) 1346-1352, ISSN 0307-0565
DOI: 10.1038/ijo.2016.72

Lifestyle precision medicine: the next generation in type 2 diabetes prevention?

Author(s): Pascal M. Mutie, Giuseppe N. Giordano, Paul W. Franks
Published in: BMC Medicine, Issue 15/1, 2017, ISSN 1741-7015
DOI: 10.1186/s12916-017-0938-x

Bicycling to Work and Primordial Prevention of Cardiovascular Risk: A Cohort Study Among Swedish Men and Women

Author(s): Anders Grøntved, Robert W. Koivula, Ingegerd Johansson, Patrik Wennberg, Lars Østergaard, Göran Hallmans, Frida Renström, Paul W. Franks
Published in: Journal of the American Heart Association, Issue 5/11, 2016, ISSN 2047-9980
DOI: 10.1161/JAHA.116.004413

Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference

Author(s): Laura J. Corbin, Vanessa Y. Tan, David A. Hughes, Kaitlin H. Wade, Dirk S. Paul, Katherine E. Tansey, Frances Butcher, Frank Dudbridge, Joanna M. Howson, Momodou W. Jallow, Catherine John, Nathalie Kingston, Cecilia M. Lindgren, Michael O’Donavan, Stephen O’Rahilly, Michael J. Owen, Colin N. A. Palmer, Ewan R. Pearson, Robert A. Scott, David A. van Heel, John Whittaker, Tim Frayling, Martin D.
Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723
DOI: 10.1038/s41467-018-03109-y

A Global Overview of Precision Medicine in Type 2 Diabetes

Author(s): Hugo Fitipaldi, Mark I. McCarthy, Jose C. Florez, Paul W. Franks
Published in: Diabetes, Issue 67/10, 2018, Page(s) 1911-1922, ISSN 0012-1797
DOI: 10.2337/dbi17-0045

The heritable basis of gene–environment interactions in cardiometabolic traits

Author(s): Alaitz Poveda, Yan Chen, Anders Brändström, Elisabeth Engberg, Göran Hallmans, Ingegerd Johansson, Frida Renström, Azra Kurbasic, Paul W. Franks
Published in: Diabetologia, Issue 60/3, 2017, Page(s) 442-452, ISSN 0012-186X
DOI: 10.1007/s00125-016-4184-0

The combined effects of FADS gene variation and dietary fats in obesity-related traits in a population from the far north of Sweden: the GLACIER Study

Author(s): Yan Chen, Angela C. Estampador, Maria Keller, Alaitz Poveda, Jonathan Dalla-Riva, Ingegerd Johansson, Frida Renström, Azra Kurbasic, Paul W. Franks, Tibor V. Varga
Published in: International Journal of Obesity, 2018, ISSN 0307-0565
DOI: 10.1038/s41366-018-0112-3

Lifestyle and precision diabetes medicine: will genomics help optimise the prediction, prevention and treatment of type 2 diabetes through lifestyle therapy?

Author(s): Paul W Franks, Alaitz Poveda
Published in: Diabetologia, Issue 60/5, 2017, Page(s) 784-792, ISSN 0012-186X
DOI: 10.1007/s00125-017-4207-5

Exposing the exposures responsible for type 2 diabetes and obesity

Author(s): P. W. Franks, M. I. McCarthy
Published in: Science, Issue 354/6308, 2016, Page(s) 69-73, ISSN 0036-8075
DOI: 10.1126/science.aaf5094

Causal inference in obesity research

Author(s): P. W. Franks, N. Atabaki-Pasdar
Published in: Journal of Internal Medicine, Issue 281/3, 2017, Page(s) 222-232, ISSN 0954-6820
DOI: 10.1111/joim.12577

Novel genetic loci associated with long-term deterioration in blood lipid concentrations and coronary artery disease in European adults

Author(s): Tibor V. Varga, Azra Kurbasic, Mattias Aine, Pontus Eriksson, Ashfaq Ali, George Hindy, Stefan Gustafsson, Jian’an Luan, Dmitry Shungin, Yan Chen, Christina-Alexandra Schulz, Peter M. Nilsson, Göran Hallmans, Inês Barroso, Panos Deloukas, Claudia Langenberg, Robert A. Scott, Nicholas J. Wareham, Lars Lind, Erik Ingelsson, Olle Melander, Marju Orho-Melander, Frida Renström, Paul W. Franks
Published in: International Journal of Epidemiology, 2017, Page(s) dyw245, ISSN 0300-5771
DOI: 10.1093/ije/dyw245

Statistical power considerations in genotype-based recall randomized controlled trials

Author(s): Naeimeh Atabaki-Pasdar, Mattias Ohlsson, Dmitry Shungin, Azra Kurbasic, Erik Ingelsson, Ewan R. Pearson, Ashfaq Ali, Paul W. Franks
Published in: Scientific Reports, Issue 6/1, 2016, ISSN 2045-2322
DOI: 10.1038/srep37307

Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions

Author(s): Dmitry Shungin, Wei Q. Deng, Tibor V. Varga, Jian'an Luan, Evelin Mihailov, Andres Metspalu, Andrew P. Morris, Nita G. Forouhi, Cecilia Lindgren, Patrik K. E. Magnusson, Nancy L. Pedersen, Göran Hallmans, Audrey Y. Chu, Anne E. Justice, Mariaelisa Graff, Thomas W. Winkler, Lynda M. Rose, Claudia Langenberg, L. Adrienne Cupples, Paul M. Ridker, Nicholas J. Wareham, Ken K. Ong, Ruth J. F. Loos, Dan
Published in: PLOS Genetics, Issue 13/6, 2017, Page(s) e1006812, ISSN 1553-7404
DOI: 10.1371/journal.pgen.1006812

Genotype-Based Recall Studies in Complex Cardiometabolic Traits

Author(s): Paul W. Franks, Nicholas J. Timpson
Published in: Circulation: Genomic and Precision Medicine, Issue 11/8, 2018, ISSN 2574-8300
DOI: 10.1161/CIRCGEN.118.001947