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Novel Approach to Systematically Characterize Exercise- and Nutrient- responsive genes in Type 2 diabetes and cardiovascular disease

Publikacje

Accessible data curation and analytics for international-scale citizen science datasets.

Autorzy: Murray B, Kerfoot E, Chen L, Deng J, Graham MS, Sudre CH, Molteni E, Canas LS, Antonelli M, Klaser K, Visconti A, Hammers A, Chan AT, Franks PW, Davies R, Wolf J, Spector TD, Steves CJ, Modat M, Ourselin S.
Opublikowane w: Sci Data, Numer 8(1), 2021, Strona(/y) 297, ISSN 2052-4463
Wydawca: Springer
DOI: 10.1038/s41597-021-01071-x

Epigenetic markers associated with metformin response and intolerance in drug-naïve patients with type 2 diabetes.

Autorzy: Sonia García-Calzón; Sonia García-Calzón; Alexander Perfilyev; Mats Martinell; Monta Ustinova; Sebastian Kalamajski; Paul W. Franks; Karl Bacos; Ilze Elbere; Jussi Pihlajamäki; Petr Volkov; Allan Vaag; Leif Groop; Marlena Maziarz; Janis Klovins; Janis Klovins; Emma Ahlqvist; Charlotte Ling
Opublikowane w: Sci Transl Med, Numer 25, 2020, ISSN 1946-6234
Wydawca: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.aaz1803

Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine

Autorzy: Deirdre K. Tobias; Jordi Merino; Abrar Ahmad; Catherine Aiken; Jamie L. Benham; Dhanasekaran Bodhini; Amy L. Clark; Kevin Colclough; Rosa Corcoy; Sara J. Cromer; Daisy Duan; Jamie L. Felton; Ellen C. Francis; Pieter Gillard; Véronique Gingras; Romy Gaillard; Eram Haider; Alice Hughes; Jennifer M. Ikle; Laura M. Jacobsen; Anna R. Kahkoska; Jarno L. T. Kettunen; Raymond J. Kreienkamp; Lee-Ling Lim;
Opublikowane w: Nat Med, Numer 29(10), 2023, Strona(/y) 2438-2457, ISSN 1078-8956
Wydawca: Nature Publishing Group
DOI: 10.1038/s41591-023-02502-5

Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium

Autorzy: Robert W. Koivula; Robert W. Koivula; Ian M Forgie; Azra Kurbasic; Ana Viñuela; Ana Viñuela; Alison Heggie; Giuseppe N. Giordano; Tue H. Hansen; Michelle Hudson; Anitra D.M. Koopman; Femke Rutters; Maritta Siloaho; Kristine H. Allin; Soren Brage; Soren Brage; Caroline Brorsson; Adem Y. Dawed; Federico De Masi; Christopher J. Groves; Tarja Kokkola; Anubha Mahajan; Mandy H Perry; Simone P. Rauh; M
Opublikowane w: Koivula , R W , Forgie , I M , Kurbasic , A , Viñuela , A , Heggie , A , Giordano , G N , Hansen , T H , Hudson , M , Koopman , A D M , Rutters , F , Siloaho , M , Allin , K H , Brage , S R , Brorsson , C A , Dawed , A Y , de Masi , F , Groves , C J , Kokkola , T , Mahajan , A , Perry , M H , Rauh , S P , Ridderstråle , M , Teare , H J A , Thomas , E L , Tura , A , Vestergaard , H , White , T ,, Numer 32, 2019, ISSN 0012-186X
Wydawca: Springer Verlag
DOI: 10.1007/s00125-019-4906-1

Engineered allele substitution at PPARGC1A rs8192678 alters human white adipocyte differentiation, lipogenesis, and PGC-1α content and turnover

Autorzy: Mi Huang; Melina Claussnitzer; Alham Saadat; Daniel E. Coral; Sebastian Kalamajski; Paul W. Franks
Opublikowane w: Diabetologia, Numer 66(7), 2023, Strona(/y) 1289-1305, ISSN 0012-186X
Wydawca: Springer Verlag
DOI: 10.1007/s00125-023-05915-6

Glucose-Dependent Insulinotropic Peptide in the High-Normal Range Is Associated With Increased Carotid Intima-Media Thickness.

Autorzy: Amra Jujic; Peter M. Nilsson; Naeimeh Atabaki-Pasdar; Anna Dieden; Tiinamaija Tuomi; Paul W. Franks; Paul W. Franks; Jens J. Holst; Signe S. Torekov; Susana Ravassa; Javier Díez; Margaretha Persson; Emma Ahlqvist; Olle Melander; Maria F. Gomez; Leif Groop; Leif Groop; Martin Magnusson
Opublikowane w: Diabetes Care, Numer 44(1), 2021, Strona(/y) 224-230, ISSN 0149-5992
Wydawca: American Diabetes Association
DOI: 10.2337/dc20-1318

The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study.

Autorzy: Robert W. Koivula; Robert W. Koivula; Naeimeh Atabaki-Pasdar; Giuseppe N. Giordano; Thomas E. White; Jerzy Adamski; Jerzy Adamski; Jimmy D. Bell; Joline W.J. Beulens; Soren Brage; Soren Brage; Søren Brunak; Søren Brunak; Federico De Masi; Federico De Masi; Emmanouil T. Dermitzakis; Emmanouil T. Dermitzakis; Ian M Forgie; Gary Frost; Torben Hansen; Torben Hansen; Tue H. Hansen; Andrew T. Hattersl
Opublikowane w: Diabetologia, Numer 63(4), 2020, Strona(/y) 744-756, ISSN 0012-186X
Wydawca: Springer Verlag
DOI: 10.1007/s00125-019-05083-6

Validity of continuous glucose monitoring for categorizing glycemic responses to diet: implications for use in personalized nutrition

Autorzy: Jordi Merino; Inbar Linenberg; Kate M Bermingham; Sajaysurya Ganesh; Elco Bakker; Linda M Delahanty; Andrew T Chan; Joan Capdevila Pujol; Jonathan Wolf; Haya Al Khatib; Paul W Franks; Tim D Spector; Jose M Ordovas; Sarah E Berry; Ana M Valdes
Opublikowane w: Am J Clin Nutr, Numer 115(6), 2022, Strona(/y) 1569-1576, ISSN 0002-9165
Wydawca: American Society for Clinical Nutrition, Inc.
DOI: 10.1093/ajcn/nqac026

Precision Medicine in Diabetes: A Consensus Report From the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

Autorzy: Wendy K. Chung; Karel A. Erion; Jose C. Florez; Andrew T. Hattersley; Marie-France Hivert; Christine G. Lee; Mark I. McCarthy; John J. Nolan; Jill M. Norris; Ewan R. Pearson; Louis H. Philipson; Allison T. McElvaine; William T. Cefalu; Stephen S. Rich; Paul W. Franks
Opublikowane w: Diabetes Care, Numer 32, 2020, ISSN 0149-5992
Wydawca: American Diabetes Association
DOI: 10.2337/dci20-0022

Human Genetic Variation at rs10071329 Correlates with Adiposity-related Traits, Modulates PPARGC1B Expression, and Alters Brown Adipocyte Function

Autorzy: Huang M, Prasad RB, Coral DE, Hjort L, Minja DTR, Mulder H, Franks PW, Kalamajski S.
Opublikowane w: Diabetes, Numer Jan 8, 2024, Strona(/y) db230531, ISSN 0012-1797
Wydawca: American Diabetes Association
DOI: 10.2337/db23-0531

Association of Established Blood Pressure Loci With 10-Year Change in Blood Pressure and Their Ability to Predict Incident Hypertension

Autorzy: Poveda A, Atabaki-Pasdar N, Ahmad S, Hallmans G, Renström F, Franks PW
Opublikowane w: J Am Heart Assoc, Numer 9(16), 2020, Strona(/y) e14513, ISSN 2047-9980
Wydawca: Wiley-Blackwell
DOI: 10.1161/jaha.119.014513

Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals.

Autorzy: Francesco Asnicar; Sarah Berry; Ana M. Valdes; Ana M. Valdes; Long H. Nguyen; Gianmarco Piccinno; David A. Drew; Emily R Leeming; Rachel J. Gibson; Caroline I. Le Roy; Haya Al Khatib; Lucy Francis; Mohsen Mazidi; Olatz Mompeo; Mireia Valles-Colomer; Adrian Tett; Francesco Beghini; Leonard Dubois; Davide Bazzani; Andrew Maltez Thomas; Chloe Mirzayi; Asya Khleborodova; Sehyun Oh; Rachel Hine; Christ
Opublikowane w: The Lancet Microbe, Vol 2, Iss 11, Pp e565-e566 (2021), Numer 30, 2021, ISSN 1078-8956
Wydawca: Nature Publishing Group
DOI: 10.1038/s41591-020-01183-8

A regression discontinuity analysis of the social distancing recommendations for older adults in Sweden during COVID-19

Autorzy: Carl Bonander; Debora Stranges; Johanna Gustavsson; Matilda Almgren; Malin Inghammar; Mahnaz Moghaddassi; Anton Nilsson; Joan Capdevila Pujol; Claire Steves; Paul W Franks; Maria F Gomez; Tove Fall; Jonas Björk; Andrew T Chan; Sébastien Ourselin; Tim D Spector; Jonathan Wolf; Beatrice Kennedy; Hugo Fitipaldi; Ulf Hammar; Marlena Maziarz; Neli Tsereteli; Nikolay Oskolkov; Georgios Varotsis; Lampr
Opublikowane w: Eur J Publ Health, Numer 32(5), 2022, Strona(/y) 799-806, ISSN 1464-360X
Wydawca: Oxford Academic
DOI: 10.1093/eurpub/ckac101

Genomic editing of metformin efficacy-associated genetic variants in SLC47A1 does not alter SLC47A1 expression.

Autorzy: MetGen Plus Consortium; Kalamajski, Sebastian; Huang, Mi; Dalla-Riva, Jonathan; Keller, Maria; Dawed, Adem Y.; Hansson, Ola; Pearson, Ewan R.; Mulder, Hindrik; Franks, Paul W.
Opublikowane w: Hum Mol Genet, Numer 31(4), 2022, Strona(/y) 491-498, ISSN 0964-6906
Wydawca: Oxford University Press
DOI: 10.1093/hmg/ddab266

App-based COVID-19 surveillance and prediction: The COVID Symptom Study Sweden

Autorzy: Beatrice Kennedy; Hugo Fitipaldi; Ulf Hammar; Marlena Maziarz; Neli Tsereteli; Nikolay Oskolkov; Georgios Varotsis; Camilla A Franks; Lampros Spiliopoulos; Hans-Olov Adami; Jonas Björk; Stefan Engblom; Katja Fall; Anna Grimby-Ekman; Jan-Eric Litton; Mats Martinell; Anna Oudin; Anna Oudin; Torbjörn Sjöström; Toomas Timpka; Carole H. Sudre; Mark Graham; Julien Lavigne du Cadet; Andrew T. Chan; R
Opublikowane w: Nat Commun, Numer 13 (1), 2021, Strona(/y) 2110, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-022-29608-7

Exposome-wide ranking of modifiable risk factors for cardiometabolic disease traits

Autorzy: Poveda, Alaitz; Pomares-Millan, Hugo; Chen, Yan; Kurbasic, Azra; Patel, Chirag J.; Renström, Frida; Hallmans, Göran; Johansson, Ingegerd; Franks, Paul W.
Opublikowane w: Scientific Reports, Numer 12(1), 2022, Strona(/y) 4088, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-022-08050-1

Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration.

Autorzy: Henry R, Wilman; Constantinos A, Parisinos; Naeimeh, Atabaki-Pasdar; Matt, Kelly; E Louise, Thomas; Stefan, Neubauer; Anubha, Mahajan; Aroon D, Hingorani; Riyaz S, Patel; Harry, Hemingway; Paul W, Franks; Jimmy D, Bell; Rajarshi, Banerjee; Brandon, Whitcher
Opublikowane w: Journal of Hepatology, Numer 25, 2019, ISSN 1600-0641
Wydawca: Elsevier
DOI: 10.1016/j.jhep.2019.05.032

GWAS in people of Middle Eastern descent reveals a locus protective of kidney function—a cross-sectional study

Autorzy: Siham A. Mohamed; Juan Fernadez-Tajes; Paul W. Franks; Louise Bennet
Opublikowane w: BMC Medicine, Numer 20(1), 2022, Strona(/y) 76, ISSN 1741-7015
Wydawca: BioMed Central
DOI: 10.1186/s12916-022-02267-7

Next-generation epidemiology: the role of high-resolution molecular phenotyping in diabetes research.

Autorzy: Franks PW, Pomares-Millan H.
Opublikowane w: Diabetologia, Numer 63(12), 2020, Strona(/y) 2521-2532, ISSN 1432-0428
Wydawca: Springer Verlag
DOI: 10.1007/s00125-020-05246-w

Menopause is associated with postprandial metabolism, metabolic health and lifestyle: The ZOE PREDICT study.

Autorzy: Bermingham KM, Linenberg I, Hall WL, Kadé K, Franks PW, Davies R, Wolf J, Hadjigeorgiou G, Asnicar F, Segata N, Manson JE, Newson LR, Delahanty LM, Ordovas JM, Chan AT, Spector TD, Valdes AM, Berry SE.
Opublikowane w: EBioMedicine, Numer 85, 2022, Strona(/y) 104303, ISSN 2352-3964
Wydawca: Elsevier BV
DOI: 10.1016/j.ebiom.2022.104303

A saturated map of common genetic variants associated with human height

Autorzy: Yengo, Loïc; Vedantam, Sailaja; Marouli, Eirini; Sidorenko, Julia; Bartell, Eric; Sakaue, Saori; Graff, Marielisa; Eliasen, Anders U; Jiang, Yunxuan; Raghavan, Sridharan; Miao, Jenkai; Arias, Joshua D; Graham, Sarah E; Mukamel, Ronen E; Spracklen, Cassandra N; Yin, Xianyong; Chen, Shyh-Huei; Ferreira, Teresa; Highland, Heather H; Ji, Yingjie; Karaderi, Tugce; Lin, Kuang; Lüll, Kreete; Malden, De
Opublikowane w: Nature, Numer 610(7933), 2022, Strona(/y) 704-712, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-022-05275-y

Investigating the causal relationships between excess adiposity and cardiometabolic health in men and women.

Autorzy: Mutie PM, Pomares-Milan H, Atabaki-Pasdar N, Coral D, Fitipaldi H, Tsereteli N, Tajes JF, Franks PW, Giordano GN.
Opublikowane w: Diabetologia, Numer 66(2), 2023, Strona(/y) 321-335, ISSN 0012-186X
Wydawca: Springer Verlag
DOI: 10.1007/s00125-022-05811-5

Ethnic, gender and other sociodemographic biases in genome-wide association studies for the most burdensome non-communicable diseases: 2005–2022

Autorzy: Hugo, Fitipaldi; Paul W, Franks
Opublikowane w: Hum Mol Genet, Numer 32(3), 2023, Strona(/y) 520-532, ISSN 0964-6906
Wydawca: Oxford University Press
DOI: 10.1093/hmg/ddac245

How people wake up is associated with previous night's sleep together with physical activity and food intake

Autorzy: Vallat R, Berry SE, Tsereteli N, Capdevila J, Khatib HA, Valdes AM, Delahanty LM, Drew DA, Chan AT, Wolf J, Franks PW, Spector TD, Walker MP.
Opublikowane w: Nat Commun, Numer 13(1), 2022, Strona(/y) 7116, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-022-34503-2

Characterisation of Fasting and Postprandial NMR Metabolites: Insights from the ZOE PREDICT 1 Study.

Autorzy: Bermingham KM, Mazidi M, Franks PW, Maher T, Valdes AM, Linenberg I, Wolf J, Hadjigeorgiou G, Spector TD, Menni C, Ordovas JM, Berry SE, Hall WL.
Opublikowane w: Nutrients, Numer 15(11), 2023, Strona(/y) 2638, ISSN 2072-6643
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu15112638

Snack quality and snack timing are associated with cardiometabolic blood markers: the ZOE PREDICT study.

Autorzy: Bermingham KM, May A, Asnicar F, Capdevila J, Leeming ER, Franks PW, Valdes AM, Wolf J, Hadjigeorgiou G, Delahanty LM, Segata N, Spector TD, Berry SE.
Opublikowane w: Eur J Nutr., Numer 63(1), 2024, Strona(/y) 121-133, ISSN 1436-6207
Wydawca: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00394-023-03241-6

Identification of a weight loss-associated causal eQTL in<i>MTIF3</i>and the effects of<i>MTIF3</i>deficiency on human adipocyte function

Autorzy: Mi Huang; Daniel Coral; Hamidreza Ardalani; Peter Spegel; Alham Saadat; Melina Claussnitzer; Hindrik Mulder; Paul W Franks; Sebastian Kalamajski
Opublikowane w: eLife, Numer 12, 2023, Strona(/y) e84168, ISSN 2050-084X
Wydawca: eLife Sciences Publications
DOI: 10.7554/elife.84168

LRIG proteins regulate lipid metabolism via BMP signaling and affect the risk of type 2 diabetes.

Autorzy: Carl Herdenberg; Pascal M. Mutie; Ola Billing; Ahmad Sharmi Abdullah; Rona J. Strawbridge; Rona J. Strawbridge; Ingrid Dahlman; Simon Tuck; Camilla Holmlund; Peter Arner; Roger Henriksson; Paul W. Franks; Håkan Hedman
Opublikowane w: Commun Biol, Numer 4(1), 2021, Strona(/y) 90, ISSN 2399-3642
Wydawca: Nature Portfolio
DOI: 10.1038/s42003-020-01613-w

ADA/EASD Precision Medicine in Diabetes Initiative: An International Perspective and Future Vision for Precision Medicine in Diabetes

Autorzy: John J. Nolan; Anna R. Kahkoska; Zhila Semnani-Azad; Marie-France Hivert; Linong Ji; Viswanathan Mohan; Robert H. Eckel; Louis H. Philipson; Stephen S. Rich; Chandra Gruber; Paul W. Franks
Opublikowane w: Diabetes Care, Numer 45(2), 2022, Strona(/y) 261-266, ISSN 0149-5992
Wydawca: American Diabetes Association
DOI: 10.2337/dc21-2216

A phenome-wide comparative analysis of genetic discordance between obesity and type 2 diabetes

Autorzy: Daniel E. Coral; Juan Fernandez-Tajes; Neli Tsereteli; Hugo Pomares-Millan; Hugo Fitipaldi; Pascal M. Mutie; Naeimeh Atabaki-Pasdar; Sebastian Kalamajski; Alaitz Poveda; Tyne W. Miller-Fleming; Xue Zhong; Giuseppe N. Giordano; Ewan R. Pearson; Nancy J. Cox; Paul W. Franks
Opublikowane w: Nat Metab, Numer 5(2), 2023, Strona(/y) 237-247, ISSN 2522-5812
Wydawca: Nature Portfolio
DOI: 10.1038/s42255-022-00731-5

Established BMI-associated genetic variants and their prospective associations with BMI and other cardiometabolic traits: the GLACIER Study

Autorzy: S Ahmad, A Poveda, D Shungin, I Barroso, G Hallmans, F Renström, P W Franks
Opublikowane w: International Journal of Obesity, Numer 40/9, 2016, Strona(/y) 1346-1352, ISSN 0307-0565
Wydawca: Nature Publishing Group
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Lifestyle precision medicine: the next generation in type 2 diabetes prevention?

Autorzy: Pascal M. Mutie, Giuseppe N. Giordano, Paul W. Franks
Opublikowane w: BMC Medicine, Numer 15/1, 2017, ISSN 1741-7015
Wydawca: BioMed Central
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Bicycling to Work and Primordial Prevention of Cardiovascular Risk: A Cohort Study Among Swedish Men and Women

Autorzy: Anders Grøntved, Robert W. Koivula, Ingegerd Johansson, Patrik Wennberg, Lars Østergaard, Göran Hallmans, Frida Renström, Paul W. Franks
Opublikowane w: Journal of the American Heart Association, Numer 5/11, 2016, ISSN 2047-9980
Wydawca: Wiley-Blackwell
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Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference

Autorzy: Laura J. Corbin, Vanessa Y. Tan, David A. Hughes, Kaitlin H. Wade, Dirk S. Paul, Katherine E. Tansey, Frances Butcher, Frank Dudbridge, Joanna M. Howson, Momodou W. Jallow, Catherine John, Nathalie Kingston, Cecilia M. Lindgren, Michael O’Donavan, Stephen O’Rahilly, Michael J. Owen, Colin N. A. Palmer, Ewan R. Pearson, Robert A. Scott, David A. van Heel, John Whittaker, Tim Frayling, Martin D.
Opublikowane w: Nature Communications, Numer 9/1, 2018, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-018-03109-y

A Global Overview of Precision Medicine in Type 2 Diabetes

Autorzy: Hugo Fitipaldi, Mark I. McCarthy, Jose C. Florez, Paul W. Franks
Opublikowane w: Diabetes, Numer 67/10, 2018, Strona(/y) 1911-1922, ISSN 0012-1797
Wydawca: American Diabetes Association
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The heritable basis of gene–environment interactions in cardiometabolic traits

Autorzy: Alaitz Poveda, Yan Chen, Anders Brändström, Elisabeth Engberg, Göran Hallmans, Ingegerd Johansson, Frida Renström, Azra Kurbasic, Paul W. Franks
Opublikowane w: Diabetologia, Numer 60/3, 2017, Strona(/y) 442-452, ISSN 0012-186X
Wydawca: Springer Verlag
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The combined effects of FADS gene variation and dietary fats in obesity-related traits in a population from the far north of Sweden: the GLACIER Study

Autorzy: Yan Chen, Angela C. Estampador, Maria Keller, Alaitz Poveda, Jonathan Dalla-Riva, Ingegerd Johansson, Frida Renström, Azra Kurbasic, Paul W. Franks, Tibor V. Varga
Opublikowane w: International Journal of Obesity, 2018, ISSN 0307-0565
Wydawca: Nature Publishing Group
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Lifestyle and precision diabetes medicine: will genomics help optimise the prediction, prevention and treatment of type 2 diabetes through lifestyle therapy?

Autorzy: Paul W Franks, Alaitz Poveda
Opublikowane w: Diabetologia, Numer 60/5, 2017, Strona(/y) 784-792, ISSN 0012-186X
Wydawca: Springer Verlag
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Exposing the exposures responsible for type 2 diabetes and obesity

Autorzy: P. W. Franks, M. I. McCarthy
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Wydawca: American Association for the Advancement of Science
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Causal inference in obesity research

Autorzy: P. W. Franks, N. Atabaki-Pasdar
Opublikowane w: Journal of Internal Medicine, Numer 281/3, 2017, Strona(/y) 222-232, ISSN 0954-6820
Wydawca: Blackwell Publishing Inc.
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Novel genetic loci associated with long-term deterioration in blood lipid concentrations and coronary artery disease in European adults

Autorzy: Tibor V. Varga, Azra Kurbasic, Mattias Aine, Pontus Eriksson, Ashfaq Ali, George Hindy, Stefan Gustafsson, Jian’an Luan, Dmitry Shungin, Yan Chen, Christina-Alexandra Schulz, Peter M. Nilsson, Göran Hallmans, Inês Barroso, Panos Deloukas, Claudia Langenberg, Robert A. Scott, Nicholas J. Wareham, Lars Lind, Erik Ingelsson, Olle Melander, Marju Orho-Melander, Frida Renström, Paul W. Franks
Opublikowane w: International Journal of Epidemiology, 2017, Strona(/y) dyw245, ISSN 0300-5771
Wydawca: Oxford University Press
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Statistical power considerations in genotype-based recall randomized controlled trials

Autorzy: Naeimeh Atabaki-Pasdar, Mattias Ohlsson, Dmitry Shungin, Azra Kurbasic, Erik Ingelsson, Ewan R. Pearson, Ashfaq Ali, Paul W. Franks
Opublikowane w: Scientific Reports, Numer 6/1, 2016, ISSN 2045-2322
Wydawca: Nature Publishing Group
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Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions

Autorzy: Dmitry Shungin, Wei Q. Deng, Tibor V. Varga, Jian'an Luan, Evelin Mihailov, Andres Metspalu, Andrew P. Morris, Nita G. Forouhi, Cecilia Lindgren, Patrik K. E. Magnusson, Nancy L. Pedersen, Göran Hallmans, Audrey Y. Chu, Anne E. Justice, Mariaelisa Graff, Thomas W. Winkler, Lynda M. Rose, Claudia Langenberg, L. Adrienne Cupples, Paul M. Ridker, Nicholas J. Wareham, Ken K. Ong, Ruth J. F. Loos, Dan
Opublikowane w: PLOS Genetics, Numer 13/6, 2017, Strona(/y) e1006812, ISSN 1553-7404
Wydawca: PLoS Genetics
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Genotype-Based Recall Studies in Complex Cardiometabolic Traits

Autorzy: Paul W. Franks, Nicholas J. Timpson
Opublikowane w: Circulation: Genomic and Precision Medicine, Numer 11/8, 2018, ISSN 2574-8300
Wydawca: American Heart Association, Inc
DOI: 10.1161/CIRCGEN.118.001947

Lifestyle Intervention in Pregnant Women With Obesity Impacts Cord Blood DNA Methylation, Which Associates With Body Composition in the Offspring.

Autorzy: Josefine Jönsson; Kristina M Renault; Sonia García-Calzón; Alexander Perfilyev; Angela C. Estampador; Kirsten Nørgaard; Mads Vendelbo Lind; Allan Vaag; Line Hjort; Kim F. Michaelsen; Emma Malchau Carlsen; Emma Malchau Carlsen; Paul W. Franks; Charlotte Ling
Opublikowane w: Diabetes, Numer 70(4), 2021, Strona(/y) 854-866, ISSN 0012-1797
Wydawca: American Diabetes Association
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Predicting Sensitivity to Adverse Lifestyle Risk Factors for Cardiometabolic Morbidity and Mortality

Autorzy: Hugo Pomares-Millan; Alaitz Poveda; Naemieh Atabaki-Pasdar; Ingegerd Johansson; Jonas Björk; Mattias Ohlsson; Giuseppe N. Giordano; Paul W. Franks
Opublikowane w: Nutrients, Numer 14(15), 2022, Strona(/y) 3171, ISSN 2072-6643
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
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Impact of insufficient sleep on dysregulated blood glucose control under standardised meal conditions.

Autorzy: Tsereteli N, Vallat R, Fernandez-Tajes J, Delahanty LM, Ordovas JM, Drew DA, Valdes AM, Segata N, Chan AT, Wolf J, Berry SE, Walker MP, Spector TD, Franks PW
Opublikowane w: Diabetologi, Numer 65(2), 2022, Strona(/y) 356-365, ISSN 0012-186X
Wydawca: Springer Verlag
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Modest effects of dietary supplements during the COVID-19 pandemic: insights from 445 850 users of the COVID-19 Symptom Study app.

Autorzy: Louca P, Murray B, Klaser K, Graham MS, Mazidi M, Leeming ER, Thompson E, Bowyer R, Drew DA, Nguyen LH, Merino J, Gomez M, Mompeo O, Costeira R, Sudre CH, Gibson R, Steves CJ, Wolf J, Franks PW, Ourselin S, Chan AT, Berry SE, Valdes AM, Calder PC, Spector TD, Menni C.
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Exploring the relationship between social jetlag with gut microbial composition, diet and cardiometabolic health, in the ZOE PREDICT 1 cohort

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Interaction Between Type 2 Diabetes Prevention Strategies and Genetic Determinants of Coronary Artery Disease on Cardiometabolic Risk Factors

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Estimating the Direct Effect between Dietary Macronutrients and Cardiometabolic Disease, Accounting for Mediation by Adiposity and Physical Activity.

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Socioeconomic Disparities Across the Spectrum of Genetic Burden in Type 2 Diabetes and Obesity Risk

Autorzy: Paul W. Franks
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