Tracking the Dynamics of Human Metabolism using Spectroscopy-Integrated Liver-on-Chip Microdevices

Project Information

OCLD

Grant agreement ID: 681870

DOI 10.3030/681870

Project closed

EC signature date 7 July 2016

Start date 1 October 2016

End date 30 September 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 118 175,00

EU contribution € 2 118 175,00

Coordinated by

THE HEBREW UNIVERSITY OF JERUSALEM
Israel

Publications

Peer reviewed articles (7)

Circadian Effects of Drug Responses

Author(s): Yaakov Nahmias, Ioannis P. Androulakis
Published in: Annual Review of Biomedical Engineering, 2021, ISSN 1523-9829
Publisher: Annual Reviews, Inc.
DOI: 10.1146/annurev-bioeng-082120-034725

Mechanism and reversal of drug-induced nephrotoxicity on a chip

Author(s): Aaron Cohen, Konstantinos Ioannidis, Avner Ehrlich, Shaun Regenbaum, Merav Cohen, Muneef Ayyash, Sigal Shafran Tikva, Yaakov Nahmias
Published in: Science Translational Medicine, 2021, ISSN 1946-6234
Publisher: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.abd6299

Microfluidic Concentric Gradient Generator Design for High-Throughput Cell-Based Studies

Author(s): Elishai Ezra Tsur, Michal Zimerman, Idan Maor, Avner Elrich, Yaakov Nahmias
Published in: Frontiers in Bioengineering and Biotechnology, Issue 5, 2017, ISSN 2296-4185
Publisher: Frontiers in Biotechnology and Bioengineering
DOI: 10.3389/fbioe.2017.00021

Microphysiological flux balance platform unravels the dynamics of drug induced steatosis

Author(s): Avner Ehrlich, Sabina Tsytkin-Kirschenzweig, Konstantinos Ioannidis, Muneef Ayyash, Anne Riu, Reine Note, Gladys Ouedraogo, Jan Vanfleteren, Merav Cohen, Yaakov Nahmias
Published in: Lab on a Chip, Issue 18/17, 2018, Page(s) 2510-2522, ISSN 1473-0197
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8lc00357b

Nuclear receptors control pro-viral and antiviral metabolic responses to hepatitis C virus infection

Author(s): Gahl Levy, Naomi Habib, Maria Angela Guzzardi, Daniel Kitsberg, David Bomze, Elishai Ezra, Basak E Uygun, Korkut Uygun, Martin Trippler, Joerg F Schlaak, Oren Shibolet, Ella H Sklan, Merav Cohen, Joerg Timm, Nir Friedman, Yaakov Nahmias
Published in: Nature Chemical Biology, Issue 12/12, 2016, Page(s) 1037-1045, ISSN 1552-4450
Publisher: Nature Publishing Group
DOI: 10.1038/nchembio.2193

High-Reynolds Microfluidic Sorting of Large Yeast Populations

Author(s): Eliezer Keinan, Ayelet Chen Abraham, Aaron Cohen, Alexander I. Alexandrov, Reshef Mintz, Merav Cohen, Dana Reichmann, Daniel Kaganovich, Yaakov Nahmias
Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-018-31726-6

Challenges and Opportunities in the Design of Liver-on-Chip Microdevices

Author(s): Avner Ehrlich, Daniel Duche, Gladys Ouedraogo, Yaakov Nahmias
Published in: Annual Review of Biomedical Engineering, Issue 21/1, 2019, Page(s) 219-239, ISSN 1523-9829
Publisher: Annual Reviews, Inc.
DOI: 10.1146/annurev-bioeng-060418-052305

Intellectual Property Rights

Patent (3)

METHOD TO REPRODUCE CIRCADIAN RHYTHMS ON A MICROFLUIDIC CHIP

Application/Publication number: 20 18051404
Date: 2018-12-27
Applicant(s): THE HEBREW UNIVERSITY OF JERUSALEM

METHOD TO REPRODUCE CIRCADIAN RHYTHMS ON A MICROFLUIDIC CHIP

Application/Publication number: 20 18051404
Date: 2018-12-27

METHOD TO REPRODUCE CIRCADIAN RHYTHMS ON A MICROFLUIDIC CHIP

Application/Publication number: 20 18051404
Date: 2018-12-27