Multi-scale analysis of the interplay between cell morphology and cell-cell signaling

Project Information

MorphoNotch

Grant agreement ID: 682161

DOI 10.3030/682161

Project closed

EC signature date 25 May 2016

Start date 1 June 2016

End date 31 May 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 000 000,00

EU contribution € 2 000 000,00

Coordinated by

TEL AVIV UNIVERSITY
Israel

Publications

Other (2)

Mechano-signaling feedback underlies precise inner hair cell patterning in the organ of Corti

Author(s): Roie Cohen, Shahar Taiber, Olga Loza, Shahar Kasirer, Shiran Woland, David Sprinzak
Published in: BioRxiv, Issue NA, 2022, Page(s) NA
Publisher: CSHL
DOI: 10.1101/2022.01.24.477468

Matrix stiffness regulates Notch signaling activity in endothelial cells

Author(s): Maibritt Kretschmer, Rose Mamistvalov, David Sprinzak, Angelika M. Vollmar, Stefan Zahler
Published in: BioRxiv, Issue NA, 2022, Page(s) NA
Publisher: CSHL
DOI: 10.1101/2022.04.20.488899

Peer reviewed articles (5)

Mechanical forces drive ordered patterning of hair cells in the mammalian inner ear

Author(s): Roie Cohen, Liat Amir-Zilberstein, Micha Hersch, Shiran Woland, Olga Loza, Shahar Taiber, Fumio Matsuzaki, Sven Bergmann, Karen B. Avraham, David Sprinzak
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-18894-8

Cell-Cell Contact Area Affects Notch Signaling and Notch-Dependent Patterning

Author(s): Oren Shaya, Udi Binshtok, Micha Hersch, Dmitri Rivkin, Sheila Weinreb, Liat Amir-Zilberstein, Bassma Khamaisi, Olya Oppenheim, Ravi A. Desai, Richard J. Goodyear, Guy P. Richardson, Christopher S. Chen, David Sprinzak
Published in: Developmental Cell, Issue 40/5, 2017, Page(s) 505-511.e6, ISSN 1534-5807
Publisher: Cell Press
DOI: 10.1016/j.devcel.2017.02.009

Mechanical forces shaping the development of the inner ear.

Author(s): Roie Cohen; David Sprinzak
Published in: Mechanical forces shaping the development of the inner ear, Issue 120/19, 2021, Page(s) 4142-4148, ISSN 0006-3495
Publisher: Biophysical Society
DOI: 10.1016/j.bpj.2021.06.036

Roadmap for the multiscale coupling of biochemical and mechanical signals during development.

Author(s): Pierre-François Lenne; Ed Munro; Idse Heemskerk; Aryeh Warmflash; Laura Bocanegra-Moreno; Kasumi Kishi; Anna Kicheva; Yuchen Long; Antoine Fruleux; Antoine Fruleux; Arezki Boudaoud; Arezki Boudaoud; Timothy E. Saunders; Paolo Caldarelli; Paolo Caldarelli; Paolo Caldarelli; Arthur Michaut; Arthur Michaut; Jerome Gros; Jerome Gros; Yonit Maroudas-Sacks; Kinneret Keren; Edouard Hannezo; Zev J. Gartn
Published in: Physical biology, Issue 18/4, 2021, Page(s) 041501, ISSN 1478-3967
Publisher: Institute of Physics Publishing
DOI: 10.1088/1478-3975/abd0db

Dynamic spatiotemporal coordination of neural stem cell fate decisions occurs through local feedback in the adult vertebrate brain

Author(s): Nicolas Dray, Laure Mancini, Udi Binshtok, Felix Cheysson, Willy Supatto, Pierre Mahou, Sébastien Bedu, Sara Ortica, Emmanuel Than-Trong, Monika Krecsmarik, Sébastien Herbert, Jean-Baptiste Masson, Jean-Yves Tinevez, Gabriel Lang, Emmanuel Beaurepaire, David Sprinzak, Laure Bally-Cuif
Published in: Cell Stem Cell, Issue 28/8, 2021, Page(s) 1457-1472.e12, ISSN 1934-5909
Publisher: Cell Press
DOI: 10.1016/j.stem.2021.03.014

Book chapters (1)

Modeling the Notch Response

Author(s): Udi Binshtok, David Sprinzak
Published in: Molecular Mechanisms of Notch Signaling, Issue 1066, 2018, Page(s) 79-98, ISBN 978-3-319-89511-6
Publisher: Springer International Publishing
DOI: 10.1007/978-3-319-89512-3_5