Skip to main content

Semi-Artificial Photosynthesis with Wired Enzymes

Objective

Nature has been harnessing solar energy to drive endergonic life-sustaining reactions such as photosynthesis for billions of years. However, the overall biological processes are inefficient despite the evolution of efficient enzymes for carrying out specific reactions. Currently, there is an urgent need to develop superior strategies for the large scale conversion of solar energy into a renewable chemical fuel through artificial photosynthesis, which uses the same fundamental science as natural photosynthesis. Here we integrate the strengths of both natural and artificial photosynthesis to explore novel pathways for efficient solar-to-chemical conversion, which are otherwise inaccessible to either field alone.

In aim 1, we develop advanced materials and strategies for the rational integration of photosynthetic enzymes into photoelectrochemical cells. A platform will be established in which enzymes can be artificially coupled to light absorbers, and also be wired together to perform novel chemical reactions.

In aim 2, we adapt advanced analytical techniques, including scanning electrochemical microscopy and time-resolved spectroscopy, to gain mechanistic insights into the nature, extent, and mechanism of the enzyme-material interaction. This will aid rational cell design and shed light into reaction bottlenecks.

In aim 3, we wire the enzyme-electrodes together in rational combinations to arrive at novel and efficient pathways for performing solar-to-fuel conversions. We will demonstrate the efficient coupling of solar energy harvesting with water oxidation and proton/carbon dioxide reduction.

This integrated approach will lead the emergent field of semi-artificial photosynthesis beyond conventional solar fuels research. It will probe into the strengths and weaknesses of biological processes, and be used to explore how other processes (e.g. nitrogen fixation, C–H bond activation) can be more efficiently re-wired or be coupled to photochemistry.

Call for proposal

ERC-2015-CoG
See other projects for this call

Funding Scheme

ERC-COG - Consolidator Grant

Host institution

THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
Address
Trinity Lane The Old Schools
CB2 1TN Cambridge
United Kingdom
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 960 289

Beneficiaries (1)

THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom
EU contribution
€ 1 960 289
Address
Trinity Lane The Old Schools
CB2 1TN Cambridge
Activity type
Higher or Secondary Education Establishments