Spatial organization of DNA repair within the nucleus

Project Information

3D-REPAIR

Grant agreement ID: 682939

DOI

10.3030/682939

Project closed

EC signature date 19 December 2016

Start date 1 March 2017

End date 30 April 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 999 750,00

EU contribution

€ 1 999 750,00

Coordinated by

THE UNIVERSITY OF SUSSEX
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (5)

AHNAK controls 53BP1-mediated p53 response by restraining 53BP1 oligomerization and phase separation

Author(s): Indrajeet Ghodke, Michaela Remisova, Audrey Furst, Sinan Kilic, Bernardo Reina-San-Martin, Anna R Poetsch, Matthias Altmeyer, Evi Soutoglou
Published in: Molecular Cell, 2021, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2021.04.010

WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks

Author(s): Pierre Caron, Tibor Pankotai, Wouter W Wiegant, Maxim A X Tollenaere, Audrey Furst, Celine Bonhomme, Angela Helfricht, Anton de Groot, Albert Pastink, Alfred C O Vertegaal, Martijn S Luijsterburg, Evi Soutoglou, Haico van Attikum
Published in: Genes and Development, 2019, ISSN 0890-9369
Publisher: Cold Spring Harbor Laboratory Press
DOI: 10.1101/gad.321943.118

Heterochromatic repeat clustering imposes a physical barrier on homologous recombination to prevent chromosomal translocations

Author(s): Ioanna Mitrentsi, Jieqiong Lou, Adèle Kerjouan, John Verigos, Bernardo Reina-San-Martin, Elizabeth Hinde, Evi Soutoglou
Published in: Molecular Cell, 2022, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2022.03.033

Activation of homologous recombination in G1 preserves centromeric integrity

Author(s): Duygu Yilmaz, Audrey Furst, Karen Meaburn, Aleksandra Lezaja, Yanlin Wen, Matthias Altmeyer , Bernardo Reina-San-Martin , Evi Soutoglou
Published in: Nature, 2021, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-021-04200-z

Transcription and mRNA export machineries SAGA and TREX-2 maintain monoubiquitinated H2B balance required for DNA repair.

Author(s): Evangelista FM, Maglott-Roth A, Stierle M, Brino L, Soutoglou E, Tora L
Published in: Journal of Cell Biology, 2018, ISSN 0021-9525
Publisher: Rockefeller University Press
DOI: 10.1083/jcb.201803074