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Clinical research for the validation of a non-invasive medical imaging device for dermatological diagnoses

Objective

Diagnosis and study of many diseases in dermatology, including cancers, mainly depend on biopsy and histopathological analysis of tissue at the cellular-level using an optical microscope. This medical procedure implies to perform a biopsy, i.e. to excise a portion of tissue, then to freeze and cut the sample into slices of a few micrometers thickness and use specific dyes. This procedure is painful and potentially dangerous for the patient. Moreover it is time-consuming and may introduce structural deformation or damages.
Skin diseases like Melanoma are rapidly growing throughout the world. About 12 millions biopsies are performed each year by dermatologists. As a minor surgical act, the biopsy process involves pain, possible scarring, and stress during the 15 days before reception of analyses results. In 60% of the cases, the skin anomaly is benign and do not necessitate further treatment. However, the patients need to consult another time with the dermatologist for the announcement of the results of the biopsy, which incurs extra medical costs and time. Moreover, as symptoms are detected on a macroscopic-level with surface criteria (color, form and size of the lesion), the dermatologist misses over one third of the pathologies. Finally, as the tissue excision is visually performed, 40% of reoperation is necessary to remove the entire tumor.
DERMAE is a highly recognized and awarded innovative project that solves this major healthcare issue by developing an innovative instrument capable of producing in situ images of biological tissues similar to histological sections. This non- invasive imaging technique will be able to image in real time the internal structures (up to 1 mm deep) of biological tissues at the cellular level (about 1 μm resolution). This imaging technology will constitute a new diagnostic tool that may revolutionize the medical procedures in dermatological diagnoses.

Fields of science (EuroSciVoc)

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Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

SME-1 - SME instrument phase 1

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-SMEInst-2014-2015

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Coordinator

DAMAE MEDICAL
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 50 000,00
Address
BATIMENT 503 - CAMPUS SCIENTIFIQUE D'ORSAY
91400 Orsay
France

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Ile-de-France Ile-de-France Essonne
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 71 429,00
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