Objective Ananda Pharma GmbH qualified a plant derived active pharmaceutical ingredient (API) for specific heart diseases. In nanomolar doses the substance protects cardiomyocytes by stabilizing the Na+/K+ -ATPase. The API enables ischemic preconditioning and has a balancing effect on the energy metabolism of cardiomyocytes by enhancing the turnover of lactate to ATP. The specific mode of action conveys a larger therapeutic range which means a smaller risk for unwanted side effects compared to similar substances.The API targets mainly on the small vessels and the myocardial cell, rather than on the large vessels, and therefore can be useful to distinguish between relevant obstructive coronary atherosclerosis and the actual ischemia in the microvasculature or in the myocardial cell itself. These properties convey the great potential as a new diagnostic medical device for patients with angina pectoris due to ischemic heart conditions. Therefore Ananda Pharma GmbH developed AnandaCor®, an innovative tablet formulation of the active pharmaceutical ingredient.Since cardiovascular and ischemic heart conditions are highly prevalent in all industrialized countries, with over 2 million deaths per year and estimated external costs of nearly 110 billion € per annum in the European Union alone, there is an urgent need for effective diagnostic investigation. Fields of science medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsmedical and health sciencesclinical medicinecardiologycardiovascular diseasesarteriosclerosis Programme(s) H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and well-being Main Programme H2020-EU.3.1.3. - Treating and managing disease Topic(s) PHC-12-2015-1 - Clinical research for the validation of biomarkers and/or diagnostic medical devices Call for proposal H2020-SMEInst-2014-2015 See other projects for this call Sub call H2020-SMEINST-1-2015 Funding Scheme SME-1 - SME instrument phase 1 Coordinator ANANDA PHARMA GMBH Net EU contribution € 50 000,00 Address Karl liebknecht strasse 94 14482 Potsdam Germany See on map Region Brandenburg Brandenburg Potsdam Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 21 429,00
