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Non-invasive monitoring of perinatal health through multiparametric digital representation of clinically relevant functions for improving clinical intervention in neonatal units (Digi-NewB)

Objective

Using the clinical and signal data (cardiac and respiratory traces, video quantification of movement and sound) from a large cohort of hospitalised newborn and pregnant women recordings Digi-NewB aims to propose a new decision support system (DSS). This DSS will assist the clinician in his decision-making through non-invasive monitoring of sepsis risk and of cardio-respiratory and neurobehavioral maturations. The objective is to reduce mortality, morbidity and health costs for the hospitalised newborns. More precisely the proposal consist in: i) implementing a large targeted prospective multicentre neonatal cohort, recruited in six university hospitals, ii) identifying the most relevant composite indices to be included in the DSS iii) validating DSS acceptability and usability in the clinical management of the identified complex situations. To achieve these goals, a consortium has been constituted, under the coordination of a paediatric clinical network (GCS HUGO-France), with two SME (Voxygen-France and Syncrophi-Ireland) and four university groups with multidisciplinary expertise: in signal processing (INESC-Portugal and LTSI-UR1 France), in multivariate analyses (TUT-Finland) and in user centred design approach (NUIG-Ireland). The proposed new class of monitoring will lead to development of novel preventive and therapeutic strategies to counteract late diagnosis of sepsis and inappropriate evaluation of maturity. This will result in i) a decrease in sepsis related death and morbidity through early and personalized prescription of antibiotics, ii) a decrease in the risks of severe cardio-respiratory events and inadequate prolongation of hospitalization iii) a decrease in health costs. At the end of the Digi-NewB program the opportunity to productise the results will be evaluated. It would be a strong 'next generation' product which would secure a good market position. Feasibly development work will be carried out by the SME industrial partners.

Call for proposal

H2020-PHC-2014-2015

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Sub call

H2020-PHC-2015-single-stage

Coordinator

GCS HOPITAUX UNIVERSITAIRES GRAND OUEST
Net EU contribution
€ 30 001,25
Non-EU contribution
€ 0,00

Participants (12)

Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

CENTRE HOSPITALIER UNIVERSITAIRE DE RENNES
France
Net EU contribution
€ 821 279,00
Address
Rue Henri Le Guilloux -Hopital 2
35033 Rennes Cedex 9

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Region
Bretagne Bretagne Ille-et-Vilaine
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS
France
Net EU contribution
€ 70 005,00
Address
Boulevard Tonelle 2
37044 Tours Cedex 9

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Region
Centre — Val de Loire Centre — Val de Loire Indre-et-Loire
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

CENTRE HOSPITALIER UNIVERSITAIRE D'ANGERS
France
Net EU contribution
€ 52 505,00
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE BREST
France
Net EU contribution
€ 70 005,00
Address
Avenue Marechal Foch 5
29609 Brest

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Region
Bretagne Bretagne Finistère
Activity type
Research Organisations
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

CENTRE HOSPITALIER UNIVERSITAIRE DE POITIERS
France
Net EU contribution
€ 36 255,00
Address
Rue De La Miletrie 2
86021 Poitiers Cedex

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Region
Nouvelle-Aquitaine Poitou-Charentes Vienne
Activity type
Research Organisations
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

CENTRE HOSPITALIER UNIVERSITAIRE DE NANTES
France
Net EU contribution
€ 70 005,00
Address
Allee De L'ile Gloriette 5
44093 Nantes

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Region
Pays de la Loire Pays de la Loire Loire-Atlantique
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSITE DE RENNES I
France
Net EU contribution
€ 956 235,00
Address
Rue Du Thabor 2
35065 Rennes Cedex

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Region
Bretagne Bretagne Ille-et-Vilaine
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
TAMPEREEN KORKEAKOULUSAATIO SR
Finland
Net EU contribution
€ 400 000,00
Address
Kalevantie 4
33100 Tampere

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Region
Manner-Suomi Länsi-Suomi Pirkanmaa
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
VOXYGEN SAS
France
Net EU contribution
€ 620 000,00
Address
Pole Phoenix Route Du Radome
22560 Pleumeur Bodou

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Bretagne Bretagne Côtes-d’Armor
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
INESC TEC - INSTITUTO DE ENGENHARIADE SISTEMAS E COMPUTADORES, TECNOLOGIA E CIENCIA
Portugal
Net EU contribution
€ 280 000,00
Address
Rua Dr Roberto Frias Campus Da Feup
4200 465 Porto

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Region
Continente Norte Área Metropolitana do Porto
Activity type
Research Organisations
Non-EU contribution
€ 0,00
NATIONAL UNIVERSITY OF IRELAND GALWAY
Ireland
Net EU contribution
€ 611 750,00
Address
University Road
H91 Galway

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Region
Ireland Eastern and Midland Dublin
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
SYNCROPHI SYSTEMS LTD
Ireland
Net EU contribution
€ 439 640,00
Address
Unit 12 Galway Technology Park
Galway

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00