Resultado final Demonstrators, pilots, prototypes (6) Dissemination materials - third release Diverse materials, periodically updated. They include brochures, newsletters and at least one short animation or video. Dissemination materials - first release Diverse materials, periodically updated. They include brochures, newsletters and at least one short animation or video. Dissemination materials - second release Updated dissemination materials. They include brochures, newsletters and at least one short animation or video. The BD2Decide visualization mock-ups concepts First conceptual mock-ups prototypes illustrating the design of the BD2Decide clinical DSS and Visual analytics tools. The BD2Decide visualization mock-ups Functional and working prototype of mock-ups illustrating the design of the BD2Decide clinical DSS and Visual analytics tools. User interaction sketches Static representation of the most relevant user I/Fs especially visualizations. Documents, reports (13) Technology validation report Report documenting the technical verification methodology and results and the relevant system performance indicators. Tumor & Lymph-nodes segmentation features Description of feature sets, Image processing and analysis algorithms for the segmentation and feature extraction of Tumors and Lymph nodes in MRI. Impacts assessment Document reporting the measurements of KPI for usability and technology acceptance and overall impacts from health technology assessment. Ethics report Document highlighting the addressed and implemented actions in compliance to Ethical and Legal obligations and regulations. Security and Standards for Clinical data The BD2Decide Security features documentation. Communication plan and strategy - final edition Final release of the communication plan and strategy, updated with the communication and dissemination activities foreseen until and after the end of the project. Quality Plan and Risk assessment Report indicating the estimated risks, the overall QA actions foreseen in the project and the relevant checkpoints. Communication plan and strategy Document describing the plan for dissemination and communications, periodically updated (at month 18 and month 30) Collected population data Report describing the external data made available to the project. Usability Evaluation results A cumulative report presenting the findings of the all usability evaluation sessions in each stage of design and development. User needs and use cases Description of users requirements including scenarios of use, workflows schemes and sample use cases. The document will define eventual technical requirements and security and privacy aspects to be considered in the technology development. System architecture Technical description of the overall architecture including relevant UML diagrams. Communications plan and strategy - second release Second release of the communication plan and strategy, updated with new communication and dissemination activities. Other (6) The Clinical DSS tool suite The final prototype release of the Clinical DSS tool suite to be integrated to the BD2Decide platform, accompanied by its user manual. The Visual Analytics tool The final prototype release of the Visual Analytics tool to be integrated to the BD2Decide platform, accompanied by its user manual. Cost-utility analysis tool A tool to quantify the anticipated net gain in predictive accuracy for additional sources of data Software implementation of the tool in R. Multilayer data acquisition and management services The services enabling the acquisition and management of data from multiple different data source. The IPDA prototype Prototype of Interactive Patient's co-Decision tool. Knowledge Management System The Knowledge Management System features documentation. Websites, patent fillings, videos etc. (1) Project web site Project website for the public, scientists,and with a private area for documents sharing. Publicaciones Conference proceedings (8) Big Data for Head & Neck Cancer (Workshop on BIG DATA TO IMPROVE OUTCOMES, PROCESS AND SERVICES IN HEALTH) Autores: Giuseppe Fico Publicado en: 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2017 Editor: IEEE Definition of a Decision Support System to Support Research on Head and Neck Cancer Autores: Laura Lopez Perez, Liss Hernandez, Giuseppe Fico, and Maria Teresa Arredondo Publicado en: 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Korea, July 2017, 2017 Editor: IEEE A computerized decision support system for head and neck cancer. In IEEE Conference on Biomedical and Health Informatics. Autores: Hernandez, L., Lopez-Perez, L., Fico, G., Fernández, A., Ugena, A., Guillén, S., Cabrera, M. F., Arredondo, M. T. Publicado en: IEEE Conference on Biomedical and Health Informatics, Issue Annually, 2018 Editor: IEEE Integration of Radiomics Information in a Computerized Decision Support System for Research on Head and Neck Cancer. In 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Autores: Alberto Vazquez, Liss Hernandez, Laura Lopez-Perez, Ana Ugena, Sergio Guillen, Maria T. Arredondo and Giuseppe Fico, Member Publicado en: 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Issue Annually, 2018 Editor: IEEE Genomics features (GF) and integration with MRI radiomics features (RF) to develop a prognostic model in oral cavity squamous cell carcinoma (OSCC) Autores: S. Cavalieri, L. De Cecco, G. Calareso, M. Silva, S.E. Gazzani, M. Bologna, I. Nauta, F. Wesseling, L. Lopez Perez, R. Shefi, V. Tountopoulos, G. Fico, K. Scheckenbach, R.H. Brakenhoff, F. Hoebers, S. Canevari, T. Poli, L. Licitra, L. Mainardi, B. Publicado en: ESMO 2018 Congress, 2018 Editor: ESMO Integrating population data in a computerized Decision Support System for Head and Neck Cancer Autores: Laura Lopez-Perez, Liss Hernandez, Laura Pfaff, Annalisa Trama, Gemma Gatta, Silvia Francisci, Sandra Mallone, Elena Martinelli, Ana Ugena, Stefano Cavalieri, Lisa Licitra, Maria T. Arredondo, Giuseppe Fico Publicado en: 2019 IEEE EMBS International Conference on Biomedical & Health Informatics (BHI), 2019, Page(s) 1-4, ISBN 978-1-7281-0848-3 Editor: IEEE DOI: 10.1109/bhi.2019.8834548 BD2Decide: Big Data and Models for Personalized Head and Neck Cancer Decision Support Autores: Laura Lopez-Perez, Liss Hernandez, Manuel Ottaviano, Elena Martinelli, Tito Poli, Lisa Licitra, Maria T. Arredondo, Giuseppe Fico Publicado en: 2019 IEEE 32nd International Symposium on Computer-Based Medical Systems (CBMS), 2019, Page(s) 67-68, ISBN 978-1-7281-2286-1 Editor: IEEE DOI: 10.1109/cbms.2019.00024 Designing an ontology for Head and Neck Cancer research Autores: Liss Hernandez, Laura Lopez-Perez, Ana M. Ugena, Maria T. Arredondo, Giuseppe Fico Publicado en: 2019 IEEE EMBS International Conference on Biomedical & Health Informatics (BHI), 2019, Page(s) 1-5, ISBN 978-1-7281-0848-3 Editor: IEEE DOI: 10.1109/bhi.2019.8834473 Peer reviewed articles (19) EP-1061: Towards a validated Decision Aid Tool for advanced larynx cancer patients Autores: A.J. Berlanga, M. Petersen, F. Hoebers, S. Delbressine, M. Van den Breke, P. Lambin Publicado en: Radiotherapy and Oncology, Issue 123, 2017, Page(s) S583-S584, ISSN 0167-8140 Editor: Elsevier BV DOI: 10.1016/S0167-8140(17)31497-4 Quantitative assessment of Zirconium-89 labeled cetuximab using PET/CT imaging in patients with advanced head and neck cancer: a theragnostic approach Autores: Aniek J.G. Even, Olga Hamming-Vrieze, Wouter van Elmpt, Véronique J.L. Winnepenninckx, Jolien Heukelom, Margot E.T. Tesselaar, Wouter V. Vogel, Ann Hoeben, Catharina M.L. Zegers, Daniëlle J. Vugts, Guus A.M.S. van Dongen, Harry Bartelink, Felix M. Mottaghy, Frank Hoebers, Philippe Lambin Publicado en: Oncotarget, 2017, ISSN 1949-2553 Editor: Impact Journals DOI: 10.18632/oncotarget.13910 Gene Expression Signatures for Head and Neck Cancer Patient Stratification: Are Results Ready for Clinical Application? Autores: Luca Tonella, Marco Giannoccaro, Salvatore Alfieri, Silvana Canevari, Loris De Cecco Publicado en: Current Treatment Options in Oncology, Issue 18/5, 2017, ISSN 1527-2729 Editor: Current Science Inc. DOI: 10.1007/s11864-017-0472-2 Are Fusion Transcripts in Relapsed/Metastatic Head and Neck Cancer Patients Predictive of Response to Anti-EGFR Therapies? Autores: Paolo Bossi, Marco Siano, Cristiana Bergamini, Maria Cossu Rocca, Andrea P. Sponghini, Marco Giannoccaro, Luca Tonella, Alessandro Paoli, Edoardo Marchesi, Federica Perrone, Silvana Pilotti, Laura D. Locati, Silvana Canevari, Lisa Licitra, Loris De Cecco Publicado en: Disease Markers, Issue 2017, 2017, Page(s) 1-9, ISSN 0278-0240 Editor: IOS Press DOI: 10.1155/2017/6870614 Radiomics: the bridge between medical imaging and personalized medicine Autores: Philippe Lambin, Ralph T.H. Leijenaar, Timo M. Deist, Jurgen Peerlings, Evelyn E.C. de Jong, Janita van Timmeren, Sebastian Sanduleanu, Ruben T.H.M. Larue, Aniek J.G. Even, Arthur Jochems, Yvonka van Wijk, Henry Woodruff, Johan van Soest, Tim Lustberg, Erik Roelofs, Wouter van Elmpt, Andre Dekker, Felix M. Mottaghy, Joachim E. Wildberger, Sean Walsh Publicado en: Nature Reviews Clinical Oncology, Issue 14/12, 2017, Page(s) 749-762, ISSN 1759-4774 Editor: Nature Publishing Group DOI: 10.1038/nrclinonc.2017.141 Feature selection methodology for longitudinal cone-beam CT radiomics Autores: Janna E. van Timmeren, Ralph T. H. Leijenaar, Wouter van Elmpt, Bart Reymen, Philippe Lambin Publicado en: Acta Oncologica, Issue 56/11, 2017, Page(s) 1537-1543, ISSN 0284-186X Editor: Taylor & Francis DOI: 10.1080/0284186x.2017.1350285 Predictive and prognostic value of CT based radiomics signature in locally advanced head and neck cancers patients treated with concurrent chemoradiotherapy or bioradiotherapy and its added value to Human Papillomavirus status Autores: Dan Ou, Pierre Blanchard, Silvia Rosellini, Antonin Levy, France Nguyen, Ralph T.H. Leijenaar, Ingrid Garberis, Philippe Gorphe, François Bidault, Charles Ferté, Charlotte Robert, Odile Casiraghi, Jean-Yves Scoazec, Philippe Lambin, Stephane Temam, Eric Deutsch, Yungan Tao Publicado en: Oral Oncology, Issue 71, 2017, Page(s) 150-155, ISSN 1368-8375 Editor: Pergamon Press Ltd. DOI: 10.1016/j.oraloncology.2017.06.015 Assessment of Stability and Discrimination Capacity of Radiomic Features on Apparent Diffusion Coefficient Images Autores: Marco Bologna, Valentina D. A. Corino, Eros Montin, Antonella Messina, Giuseppina Calareso, Francesca G. Greco, Silvana Sdao, Luca T. Mainardi Publicado en: Journal of Digital Imaging, Issue 31/6, 2018, Page(s) 879-894, ISSN 0897-1889 Editor: Springer Verlag DOI: 10.1007/s10278-018-0092-9 Post-radiochemotherapy PET radiomics in head and neck cancer - The influence of radiomics implementation on the reproducibility of local control tumor models Autores: Bogowicz M, Leijenaar RTH, Tanadini-Lang S, Riesterer O, Pruschy M, Studer G, Unkelbach J, Guckenberger M, Konukoglu E, Lambin P. Publicado en: Radiother Oncol., 2017, Page(s) 385-391, ISSN 0167-8140 Editor: Elsevier BV Pre-treatment CT radiomics to predict 3-year overall survival following chemoradiotherapy of esophageal cancer Autores: Ruben T. H. M. Larue, Remy Klaassen, Arthur Jochems, Ralph T. H. Leijenaar, Maarten C. C. M. Hulshof, Mark I. van Berge Henegouwen, Wendy M. J. Schreurs, Meindert N. Sosef, Wouter van Elmpt, Hanneke W. M. van Laarhoven, Philippe Lambin Publicado en: Acta Oncologica, Issue 57/11, 2018, Page(s) 1475-1481, ISSN 0284-186X Editor: Taylor & Francis DOI: 10.1080/0284186X.2018.1486039 Big Data in Head and Neck Cancer Autores: Carlo Resteghini, Annalisa Trama, Elio Borgonovi, Hykel Hosni, Giovanni Corrao, Ester Orlandi, Giuseppina Calareso, Loris De Cecco, Cesare Piazza, Luca Mainardi, Lisa Licitra Publicado en: Current Treatment Options in Oncology, Issue 19/12, 2018, ISSN 1527-2729 Editor: Current Science Inc. DOI: 10.1007/s11864-018-0585-2 Development and validation of a radiomic signature to predict HPV (p16) status from standard CT imaging: a multicenter study Autores: Ralph TH Leijenaar, Marta Bogowicz, Arthur Jochems, Frank JP Hoebers, Frederik WR Wesseling, Sophie H Huang, Biu Chan, John N Waldron, Brian O'Sullivan, Derek Rietveld, C Rene Leemans, Ruud H Brakenhoff, Oliver Riesterer, Stephanie Tanadini-Lang, Matthias Guckenberger, Kristian Ikenberg, Philippe Lambin Publicado en: The British Journal of Radiology, Issue 2018 Jun;91(1086), 2018, Page(s) 20170498, ISSN 0007-1285 Editor: British Institute of Radiology DOI: 10.1259/bjr.20170498 Radiomics: Big Data statt Biopsie in der Zukunft? Autores: Kathrin Scheckenbach Publicado en: Laryngo-Rhino-Otologie, Issue 97/S 01, 2018, Page(s) S114-S141, ISSN 0935-8943 Editor: Georg Thieme Verlag DOI: 10.1055/s-0043-121964 Tracking tumor biology with radiomics: A systematic review utilizing a radiomics quality score Autores: Sebastian Sanduleanu, Henry C. Woodruff, Evelyn E.C. de Jong, Janna E. van Timmeren, Arthur Jochems, Ludwig Dubois, Philippe Lambin Publicado en: Radiotherapy and Oncology, Issue 127/3, 2018, Page(s) 349-360, ISSN 0167-8140 Editor: Elsevier BV DOI: 10.1016/j.radonc.2018.03.033 Machine learning algorithms for outcome prediction in (chemo)radiotherapy: An empirical comparison of classifiers Autores: Timo M. Deist, Frank J. W. M. Dankers, Gilmer Valdes, Robin Wijsman, I-Chow Hsu, Cary Oberije, Tim Lustberg, Johan van Soest, Frank Hoebers, Arthur Jochems, Issam El Naqa, Leonard Wee, Olivier Morin, David R. Raleigh, Wouter Bots, Johannes H. Kaanders, José Belderbos, Margriet Kwint, Timothy Solberg, René Monshouwer, Johan Bussink, Andre Dekker, Philippe Lambin Publicado en: Medical Physics, Issue 45/7, 2018, Page(s) 3449-3459, ISSN 0094-2405 Editor: American Association of Physicists in Medicine DOI: 10.1002/mp.12967 Improved high-dimensional prediction with Random Forests by the use of co-data Autores: Dennis E. te Beest, Steven W. Mes, Saskia M. Wilting, Ruud H. Brakenhoff, Mark A. van de Wiel Publicado en: BMC Bioinformatics, Issue 18/1, 2017, ISSN 1471-2105 Editor: BioMed Central DOI: 10.1186/s12859-017-1993-1 Evaluation of the eighth TNM classification on p16-positive oropharyngeal squamous cell carcinomas in the Netherlands and the importance of additional HPV DNA testing Autores: I H Nauta, M M Rietbergen, A A J D van Bokhoven, E Bloemena, B I Lissenberg-Witte, D A M Heideman, R J Baatenburg de Jong, R H Brakenhoff, C R Leemans Publicado en: Annals of Oncology, Issue 29/5, 2018, Page(s) 1273-1279, ISSN 0923-7534 Editor: Oxford University Press DOI: 10.1093/annonc/mdy060 PV-0312 Distributed learning in radiomics to predict overall survival in head and neck cancer Autores: M. Bogowicz, A. Jochems, S.H. Huang, B. Chan, J.N. Waldron, B. O'Sullivan, S. Tanadini-Lang, O. Riesterer, G. Studer, J. Unkelbach, R.H. Brakenhoff, I. Nauta, S.E. Gazzani, G. Calareso, K. Scheckenbach, F. Hoebers, S. Barakat, S. Keek, S. Sanduleanu, M. Vergeer, R.C. Leemans, C.H. Terhaard, M.W. Van den Brekel, M. Guckenberger, P. Lambin Publicado en: Radiotherapy and Oncology, Issue 133, 2019, Page(s) S160-S161, ISSN 0167-8140 Editor: Elsevier BV DOI: 10.1016/s0167-8140(19)30732-7 Technical Note: Virtual phantom analyses for preprocessing evaluation and detection of a robust feature set for MRI‐radiomics of the brain Autores: Marco Bologna, Valentina Corino, Luca Mainardi Publicado en: Medical Physics, 2019, ISSN 0094-2405 Editor: American Association of Physicists in Medicine DOI: 10.1002/mp.13834 Book chapters (1) Main Barriers and Needs to Support Clinical Cancer Research via Health Informatics Autores: Laura Lopez-Perez, Silvana Canevari, Leandro Pecchia, Maria Teresa Arredondo, Lisa Licitra, Giuseppe Fico Publicado en: Future Trends in Biomedical and Health Informatics and Cybersecurity in Medical Devices - Proceedings of the International Conference on Biomedical and Health Informatics, ICBHI 2019, 17-20 April 2019, Taipei, Taiwan, Issue 74, 2020, Page(s) 174-182, ISBN 978-3-030-30635-9 Editor: Springer International Publishing DOI: 10.1007/978-3-030-30636-6_25 Buscando datos de OpenAIRE... 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