Periodic Reporting for period 1 - PRETREAT (PRoteome-based assessment of vascular disease for the Establishment of a Translational REsearch plATform)
Période du rapport: 2016-01-01 au 2017-12-31
Specific drugs have been developed to reduce vascular disease if adherence to a healthy lifestyle is low or is without effect. These include antihypertensives (lowering blood pressure drugs); antidyslipidemics (lipid lowering drugs) and antithrombotics (anti blood clotting drugs). However these drugs can be much improved upon and that is where the PRETREAT project comes in:
- PRETREAT aimed the identification of early non-invasive (blood and urine) makers of vascular disease so that intervention can be performed at a much earlier stage and hence be more effective and less aggressive (less side-effects).
- PRETREAT also aimed to better understand vascular disease by studying it on the very detailed (molecular) level using modern tools such as proteomics (analysis of all proteins that are modified in disease) and thereby proposing new drug targets.
However the partners had to reluctantly terminate the PRETREAT project after 15 months mostly due to the complicated funding scheme of the H2020 RISE action.