Deliverables Other (1) Novel photocontrollable building blocks Novel photocontrollable building blocks (in the amount 100-1000 mg), with full characterization data Websites, patent fillings, videos etc. (1) Project web-site Web-site reflecting the essence and non-confidential current results of the work under the Project Documents, reports (5) manuscript 4 manuscript of paper based on the obtained results (on novel “molecular photoswitches”) Manuscript 1 Manuscript draft to be submitted to a peer-reviewed scientific journal containing the results of the in vivo studies which will be considered not confidential Reports on biological activity studies Reports on biological activity studies of the novel peptidomimetics Manuscript 2 Manuscripts of papers based on the obtained results on the lead optimization Manuscript 3 Manuscripts of a paper based on the obtained results (novel stapled peptidomimetics) Publications Peer reviewed articles (6) Flexibility vs rigidity of amphipathic peptide conjugates when interacting with lipid bilayers Author(s): Oleg Babii, Sergii Afonin, Tim Schober, Igor V. Komarov, Anne S. Ulrich Published in: Biochimica et Biophysica Acta (BBA) - Biomembranes, Issue 1859/12, 2017, Page(s) 2505-2515, ISSN 0005-2736 Publisher: Elsevier BV DOI: 10.1016/j.bbamem.2017.09.021 Highly reactive bis-cyclooctyne-modified diarylethene for SPAAC-mediated cross-linking Author(s): Alexander V. Strizhak, Krishna Sharma, Oleg Babii, Sergii Afonin, Anne S. Ulrich, Igor V. Komarov, David R. Spring Published in: Organic & Biomolecular Chemistry, 2018, ISSN 1477-0520 Publisher: Royal Society of Chemistry DOI: 10.1039/c8ob02428f Structure–Activity Relationships of Photoswitchable Diarylethene-Based β-Hairpin Peptides as Membranolytic Antimicrobial and Anticancer Agents Author(s): Oleg Babii, Sergii Afonin, Aleksandr Yu. Ishchenko, Tim Schober, Anatoliy O. Negelia, Ganna M. Tolstanova, Liudmyla V. Garmanchuk, Liudmyla I. Ostapchenko, Igor V. Komarov, Anne S. Ulrich Published in: Journal of Medicinal Chemistry, Issue 61/23, 2018, Page(s) 10793-10813, ISSN 0022-2623 Publisher: American Chemical Society DOI: 10.1021/acs.jmedchem.8b01428 Controlling the Uptake of Diarylethene‐Based Cell‐Penetrating Peptides into Cells Using Light Author(s): Tim Schober, Ilona Wehl, Sergii Afonin, Oleg Babii, Anna Iampolska, Ute Schepers, Igor V. Komarov, Anne S. Ulrich Published in: ChemPhotoChem, 2019, ISSN 2367-0932 Publisher: Wiley-VCH Verlag GmbH & Co. KGaA DOI: 10.1002/cptc.201900019 Light-controllable dithienylethene-modified cyclic peptides: photoswitching the in vivo toxicity in zebrafish embryos Author(s): Sergii Afonin, Oleg Babii, Aline Reuter, Volker Middel, Masanari Takamiya, Uwe Strähle, Igor V Komarov, Anne S Ulrich Published in: Beilstein Journal of Organic Chemistry, Issue 16, 2020, Page(s) 39-49, ISSN 1860-5397 Publisher: Beilstein-Institut DOI: 10.3762/bjoc.16.6 Peptide drugs for photopharmacology: how much of a safety advantage can be gained by photocontrol? Author(s): Oleg Babii, Sergii Afonin, Tim Schober, Liudmyla V Garmanchuk, Liudmyla I Ostapchenko, Volodymyr Yurchenko, Sergey Zozulya, Oleksandr Tarasov, Iryna Pishel, Anne S Ulrich, Igor V Komarov Published in: Future Drug Discovery, 2020, ISSN 2631-3316 Publisher: Future Science DOI: 10.4155/fdd-2019-0033 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
