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Accelerating HIV Cure in Europe

Objective

Finding a CURE for 35 Million individuals living with HIV/AIDS is one of the great global health challenges of the 21st century. The major obstacle to HIV eradication is the persistence of latent HIV cellular reservoirs, where the integrated viral genome is transcriptionally silenced but replication-competent and can escape both Anti-Retroviral Therapy and Immune Responses. The development of novel strategies aimed at eliminating these reservoirs have become paramount in HIV research, if we want to achieve an HIV/AIDS CURE.

To accelerate the State of the Art in HIV CURE research in Europe, our EU4HIVCURE consortium brings together an intersectoral and interdisciplinary collaboration between 3 Universities, 3 Hospitals, 1 International Research Organisation from 4 European countries and 1 University from Canada. Our aim is to dissect the intricate mechanisms controlling HIV-1 latency and identify new druggable targets to develop novel latency-reversing strategies and eradicate persistent viral reservoirs by forcing HIV-1 gene expression. To facilitate continuum for translation to the clinic, we have developed an operational framework, which maximises exchange of knowledge and expertise via secondements, networking and training activities.

Field of science

  • /natural sciences/biological sciences/genetics and heredity/genome

Call for proposal

H2020-MSCA-RISE-2015
See other projects for this call

Funding Scheme

MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE)

Coordinator

UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
Address
Belfield
4 Dublin
Ireland
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 108 000

Participants (5)

UNIVERSITE DE STRASBOURG
France
EU contribution
€ 121 500
Address
Rue Blaise Pascal 4
67081 Strasbourg
Activity type
Higher or Secondary Education Establishments
MATER MISERICORDIAE UNIVERSITY HOSPITAL
Ireland
EU contribution
€ 0
Address
Eccles Street
7 Dublin
Activity type
Other
INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY
Italy
EU contribution
€ 0
Address
Padriciano 99
34149 Trieste
Activity type
Research Organisations
ASSOCIATION HOSPITALIERE DE BRUXELLES-CENTRE HOSPITALIER UNIVERSITAIRE SAINT PIERRE
Belgium
EU contribution
€ 0
Address
Rue Haute 322
1000 Bruxelles
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
UNIVERSITE LIBRE DE BRUXELLES
Belgium
EU contribution
€ 81 000
Address
Avenue Franklin Roosevelt 50
1050 Bruxelles
Activity type
Higher or Secondary Education Establishments

Partners (1)

UNIVERSITE DE MONTREAL
Canada
Address
Cp 6128 Station Centre Ville
H3C3J7 Montreal
Activity type
Higher or Secondary Education Establishments