Neurologic and Psychiatric Disorders: from synapses to networks

Deliverables

4th (Final) Annual Scientific Meeting accomplished. This will be the final scientific meeting of SynaNet

Participation of students from the University of Lisbon at the Workshops, Lectures and seminars promoted by SynaNet members quantified (3rd year)

Participation of students from the University of Lisbon at the Workshops, Lectures and seminars promoted by SynaNet members quantified (1st year)

Joint projects and student co-supervision between SynaNet in particular in the areas of interface between different disciplines quantified

2nd Annual Scientific Meeting accomplished

Participation of students from the University of Lisbon at the Workshops, Lectures and seminars promoted by SynaNet members quantified (2nd)

Participation of students from the University of Lisbon at the Workshops, Lectures and seminars promoted by SynaNet members quantified (2nd year)

SynaNet webpage made visible

Searching for OpenAIRE data...

Publications

Dual Influence of Endocannabinoids on Long-Term Potentiation of Synaptic Transmission

Author(s): Armando Silva-Cruz, Mattias Carlström, Joaquim A. Ribeiro, Ana M. Sebastião
Published in: Frontiers in Pharmacology, Issue 8, 2017, ISSN 1663-9812
DOI: 10.3389/fphar.2017.00921

Interaction between Cannabinoid Type 1 and Type 2 Receptors in the Modulation of Subventricular Zone and Dentate Gyrus Neurogenesis

Author(s): Rui S. Rodrigues, Filipa F. Ribeiro, Filipa Ferreira, Sandra H. Vaz, Ana M. Sebastião, Sara Xapelli
Published in: Frontiers in Pharmacology, Issue 8, 2017, ISSN 1663-9812
DOI: 10.3389/fphar.2017.00516

Scalable, Lightweight, Integrated and Quick-to-Assemble (SLIQ) Hyperdrives for Functional Circuit Dissection

Author(s): Li Liang, Stefan N. Oline, Justin C. Kirk, Lukas Ian Schmitt, Robert W. Komorowski, Miguel Remondes, Michael M. Halassa
Published in: Frontiers in Neural Circuits, Issue 11, 2017, ISSN 1662-5110
DOI: 10.3389/fncir.2017.00008

Chronic and acute adenosine A2A receptor blockade prevents long-term episodic memory disruption caused by acute cannabinoid CB1 receptor activation

Author(s): Francisco M. Mouro, Vânia L. Batalha, Diana G. Ferreira, Joana E. Coelho, Younis Baqi, Christa E. Müller, Luísa V. Lopes, Joaquim A. Ribeiro, Ana M. Sebastião
Published in: Neuropharmacology, Issue 117, 2017, Page(s) 316-327, ISSN 0028-3908
DOI: 10.1016/j.neuropharm.2017.02.021

Downregulated Glia Interplay and Increased miRNA-155 as Promising Markers to Track ALS at an Early Stage

Author(s): Carolina Cunha, Catarina Santos, Cátia Gomes, Adelaide Fernandes, Alexandra Marçal Correia, Ana Maria Sebastião, Ana Rita Vaz, Dora Brites
Published in: Molecular Neurobiology, 2018, ISSN 0893-7648
DOI: 10.1007/s12035-017-0631-2

Inhibition of NMDA Receptors Prevents the Loss of BDNF Function Induced by Amyloid β

Author(s): Sara R. Tanqueiro, Rita M. Ramalho, Tiago M. Rodrigues, Luísa V. Lopes, Ana M. Sebastião, Maria J. Diógenes
Published in: Frontiers in Pharmacology, Issue 9, 2018, ISSN 1663-9812
DOI: 10.3389/fphar.2018.00237

Enhanced LTP in aged rats: Detrimental or compensatory?

Author(s): Júlia Pinho, Ruben Vale, Vânia L. Batalha, Ana Rita Costenla, Raquel Dias, Diogo Rombo, Ana M. Sebastião, Alexandre de Mendonça, Maria José Diógenes
Published in: Neuropharmacology, Issue 114, 2017, Page(s) 12-19, ISSN 0028-3908
DOI: 10.1016/j.neuropharm.2016.11.017

Ex vivo model of epilepsy in organotypic slices—a new tool for drug screening

Author(s): Daniela M. Magalhães, Noémia Pereira, Diogo M. Rombo, Cláudia Beltrão-Cavacas, Ana M. Sebastião, Cláudia A. Valente
Published in: Journal of Neuroinflammation, Issue 15/1, 2018, ISSN 1742-2094
DOI: 10.1186/s12974-018-1225-2

Platinum Nanoparticle-Based Microreactors as Support for Neuroblastoma Cells

Published in: ISSN 1944-8244
DOI: 10.1021/acsami.7b10724

Tauroursodeoxycholic Acid Enhances Mitochondrial Biogenesis, Neural Stem Cell Pool, and Early Neurogenesis in Adult Rats

Author(s): Rita Soares, Filipa F. Ribeiro, Sara Xapelli, Tânia Genebra, Maria F. Ribeiro, Ana M. Sebastião, Cecília M. P. Rodrigues, Susana Solá
Published in: Molecular Neurobiology, 2018, ISSN 0893-7648
DOI: 10.1007/s12035-017-0592-5

GAT-3 Dysfunction Generates Tonic Inhibition in External Globus Pallidus Neurons in Parkinsonian Rodents

Author(s): Marine Chazalon, Elena Paredes-Rodriguez, Stéphanie Morin, Audrey Martinez, Sofia Cristóvão-Ferreira, Sandra Vaz, Ana Sebastiao, Aude Panatier, Eric Boué-Grabot, Cristina Miguelez, Jérôme Baufreton
Published in: Cell Reports, Issue 23/6, 2018, Page(s) 1678-1690, ISSN 2211-1247
DOI: 10.1016/j.celrep.2018.04.014

Glycine Receptor Activation Impairs ATP-Induced Calcium Transients in Cultured Cortical Astrocytes

Author(s): Tatiana P. Morais, David Coelho, Sandra H. Vaz, Ana M. Sebastião, Cláudia A. Valente
Published in: Frontiers in Molecular Neuroscience, Issue 10, 2018, ISSN 1662-5099
DOI: 10.3389/fnmol.2017.00444

Constrained Nonlinear-Based Optimisation Applied to Fuzzy PID Controllers Tuning

Author(s): Paulo Gil, Ana Sebastião, Catarina Lucena
Published in: Asian Journal of Control, Issue 20/1, 2018, Page(s) 135-148, ISSN 1561-8625
DOI: 10.1002/asjc.1549

VPAC 1 and VPAC 2 receptor activation on GABA release from hippocampal nerve terminals involve several different signalling pathways

Author(s): Diana Cunha-Reis, Joaquim Alexandre Ribeiro, Rodrigo F M de Almeida, Ana M Sebastião
Published in: British Journal of Pharmacology, Issue 174/24, 2017, Page(s) 4725-4737, ISSN 0007-1188
DOI: 10.1111/bph.14051

On the role of stigmergy in cognition

Author(s): Luís Correia, Ana M. Sebastião, Pedro Santana
Published in: Progress in Artificial Intelligence, Issue 6/1, 2017, Page(s) 79-86, ISSN 2192-6352
DOI: 10.1007/s13748-016-0107-z

Dissecting neurovascular coupling mechanisms: a role for adenosine A 2A receptor

Author(s): Nicholas Dale, Ana Maria Sebastião
Published in: Journal of Neurochemistry, Issue 140/1, 2017, Page(s) 10-12, ISSN 0022-3042
DOI: 10.1111/jnc.13896

Broad spectrum antiviral activity for paramyxoviruses is modulated by biophysical properties of fusion inhibitory peptides

Author(s): Cyrille Mathieu, Marcelo T. Augusto, Stefan Niewiesk, Branka Horvat, Laura M. Palermo, Giuseppina Sanna, Silvia Madeddu, Devra Huey, Miguel A. R. B. Castanho, Matteo Porotto, Nuno C. Santos, Anne Moscona
Published in: Scientific Reports, Issue 7/1, 2017, ISSN 2045-2322
DOI: 10.1038/srep43610

In Vivo Efficacy of Measles Virus Fusion Protein-Derived Peptides Is Modulated by the Properties of Self-Assembly and Membrane Residence

Author(s): T. N. Figueira, L. M. Palermo, A. S. Veiga, D. Huey, C. A. Alabi, N. C. Santos, J. C. Welsch, C. Mathieu, B. Horvat, S. Niewiesk, A. Moscona, M. A. R. B. Castanho, M. Porotto
Published in: Journal of Virology, Issue 91/1, 2016, ISSN 0022-538X
DOI: 10.1128/jvi.01554-16

siRNA-cell-penetrating peptides complexes as a combinatorial therapy against chronic myeloid leukemia using BV173 cell line as model

Author(s): Freire, JM (Freire, Joao Miguel)[ 1 ] ; de Figueiredo, IR (de Figueiredo, Ines Rego)[ 1 ] ; Valle, J (Valle, Javier)[ 2 ] ; Veiga, AS (Veiga, Ana Salome)[ 1 ] ; Andreu, D (Andreu, David)[ 2 ] ; Enguita, FJ (Enguita, Francisco J.)[ 1 ] ; Castanho, MARB (Castanho, Miguel A. R. B.)[ 1 ]
Published in: JOURNAL OF CONTROLLED RELEASE, 2017, ISSN 0168-3659
DOI: 10.1016/j.jconrel.2016.11.027

New Potent Membrane-Targeting Antibacterial Peptides from Viral Capsid Proteins

Author(s): Susana A. Dias, João M. Freire, Clara Pérez-Peinado, Marco M. Domingues, Diana Gaspar, Nuno Vale, Paula Gomes, David Andreu, Sónia T. Henriques, Miguel A. R. B. Castanho, Ana S. Veiga
Published in: Frontiers in Microbiology, Issue 8, 2017, ISSN 1664-302X
DOI: 10.3389/fmicb.2017.00775

A New Noncanonical Anionic Peptide That Translocates a Cellular Blood–Brain Barrier Model

Author(s): Sara Neves-Coelho, Rute Eleutério, Francisco Enguita, Vera Neves, Miguel Castanho
Published in: Molecules, Issue 22/10, 2017, Page(s) 1753, ISSN 1420-3049
DOI: 10.3390/molecules22101753

Mechanisms of bacterial membrane permeabilization by crotalicidin (Ctn) and its fragment Ctn(15–34), antimicrobial peptides from rattlesnake venom

Author(s): Clara Pérez-Peinado, Susana Almeida Dias, Marco M. Domingues, Aurélie H. Benfield, João Miguel Freire, Gandhi Rádis-Baptista, Diana Gaspar, Miguel A. R. B. Castanho, David J. Craik, Sónia Troeira Henriques, Ana Salomé Veiga, David Andreu
Published in: Journal of Biological Chemistry, Issue 293/5, 2018, Page(s) 1536-1549, ISSN 0021-9258
DOI: 10.1074/jbc.ra117.000125

Novel Peptides Derived from Dengue Virus Capsid Protein Translocate Reversibly the Blood–Brain Barrier through a Receptor-Free Mechanism

Author(s): Vera Neves, Frederico Aires-da-Silva, Maurício Morais, Lurdes Gano, Elisabete Ribeiro, Antónia Pinto, Sandra Aguiar, Diana Gaspar, Célia Fernandes, João D. G. Correia, Miguel A. R. B. Castanho
Published in: ACS Chemical Biology, Issue 12/5, 2017, Page(s) 1257-1268, ISSN 1554-8929
DOI: 10.1021/acschembio.7b00087

Mechanisms of Vesicular Stomatitis Virus Inactivation by Protoporphyrin IX, Zinc-Protoporphyrin IX, and Mesoporphyrin IX

Author(s): Christine Cruz-Oliveira, Andreza F. Almeida, João M. Freire, Marjolly B. Caruso, Maria A. Morando, Vivian N. S. Ferreira, Iranaia Assunção-Miranda, Andre M. O. Gomes, Miguel A. R. B. Castanho, Andrea T. Da Poian
Published in: Antimicrobial Agents and Chemotherapy, Issue 61/6, 2017, ISSN 0066-4804
DOI: 10.1128/aac.00053-17

Peptibodies: An elegant solution for a long-standing problem

Author(s): Marco Cavaco, Miguel A. R. B. Castanho, Vera Neves
Published in: Peptide Science, Issue 110/1, 2018, Page(s) e23095, ISSN 2475-8817
DOI: 10.1002/bip.23095

Neuropeptide Kyotorphin Impacts on Lipopolysaccharide-Induced Glucocorticoid-Mediated Inflammatory Response. A Molecular Link to Nociception, Neuroprotection, and Anti-Inflammatory Action

Author(s): Juliana Perazzo, Carla Lima, Montserrat Heras, Eduard Bardají, Mônica Lopes-Ferreira, Miguel Castanho
Published in: ACS Chemical Neuroscience, Issue 8/8, 2017, Page(s) 1663-1667, ISSN 1948-7193
DOI: 10.1021/acschemneuro.7b00007

Pharmacological Potential of the Endogenous Dipeptide Kyotorphin and Selected Derivatives

Author(s): Juliana Perazzo, Miguel A. R. B. Castanho, Sónia Sá Santos
Published in: Frontiers in Pharmacology, Issue 7, 2017, ISSN 1663-9812
DOI: 10.3389/fphar.2016.00530

Molecular determinants of the influenza fusion peptide activity

Author(s): Diana Lousa, Antónia R.T. Pinto, Bruno L. Victor, Alessnadro Laio, Ana S. Veiga, Miguel A.R.B. Castanho, Cláudio M. Soares
Published in: Free Radical Biology and Medicine, Issue 120, 2018, Page(s) S125, ISSN 0891-5849
DOI: 10.1016/j.freeradbiomed.2018.04.413

Designing of Artificial Peptides for an Improved Antiviral Activity

Author(s): Speranta Avram, Adina-Luminita Milac, Livia-Cristina Borcan, Dan Mihailescu, Florin Borcan, Miguel Castanho
Published in: Current Proteomics, Issue 15/4, 2018, Page(s) 258-266, ISSN 1570-1646
DOI: 10.2174/1570164615666180409151111

Quantitative analysis of molecular partition towards lipid membranes using surface plasmon resonance

Author(s): Tiago N. Figueira, João M. Freire, Catarina Cunha-Santos, Montserrat Heras, João Gonçalves, Anne Moscona, Matteo Porotto, Ana Salomé Veiga, Miguel A. R. B. Castanho
Published in: Scientific Reports, Issue 7/1, 2017, ISSN 2045-2322
DOI: 10.1038/srep45647

Challenging metastatic breast cancer with the natural defensin Pv D 1

Author(s): Tiago N. Figueira, Filipa D. Oliveira, Inês Almeida, Érica O. Mello, Valdirene M. Gomes, Miguel A. R. B. Castanho, Diana Gaspar
Published in: Nanoscale, Issue 9/43, 2017, Page(s) 16887-16899, ISSN 2040-3364
DOI: 10.1039/c7nr05872a

Motor unit number estimation (MUNE): Where are we now?

Author(s): Mamede de Carvalho, Paul E. Barkhaus, Sanjeev D. Nandedkar, Michael Swash
Published in: Clinical Neurophysiology, Issue 129/8, 2018, Page(s) 1507-1516, ISSN 1388-2457
DOI: 10.1016/j.clinph.2018.04.748

Prolongation of terminal latency of the phrenic nerve in amyotrophic lateral sclerosis – Is it clinically useful, and what are the mechanisms?

Author(s): Mamede de Carvalho
Published in: Clinical Neurophysiology, Issue 128/10, 2017, Page(s) 2094, ISSN 1388-2457
DOI: 10.1016/j.clinph.2017.07.404

Phrenic nerve stimulation is more sensitive than ultrasound measurement of diaphragm thickness in assessing early ALS progression

Author(s): Susana Pinto, Pedro Alves, Michael Swash, Mamede de Carvalho
Published in: Neurophysiologie Clinique/Clinical Neurophysiology, Issue 47/1, 2017, Page(s) 69-73, ISSN 0987-7053
DOI: 10.1016/j.neucli.2016.08.001

Diaphragm motor responses to phrenic nerve stimulation in ALS: Surface and needle recordings

Author(s): Mamede de Carvalho, Susana Pinto, Michael Swash
Published in: Clinical Neurophysiology, Issue 129/2, 2018, Page(s) 349-353, ISSN 1388-2457
DOI: 10.1016/j.clinph.2017.11.019

Fasciculation in amyotrophic lateral sclerosis: origin and pathophysiological relevance

Published in: ISSN 0022-3050
DOI: 10.1136/jnnp-2017-315574

Fasciculation: Does distance really matter?

Author(s): Mamede de Carvalho
Published in: Clinical Neurophysiology, Issue 129/2, 2018, Page(s) 462-463, ISSN 1388-2457
DOI: 10.1016/j.clinph.2017.11.021

Plasma level of club-cell (CC-16) predicts outcome in amyotrophic lateral sclerosis

Author(s): A. C. Pronto-Laborinho, M. Gromicho, M. Pereira, S. Pinto, M. do A. Barros, M. Swash, M. de Carvalho
Published in: Acta Neurologica Scandinavica, Issue 137/2, 2018, Page(s) 233-237, ISSN 0001-6314
DOI: 10.1111/ane.12851

Cramps and vinpocetine in ALS

Author(s): Mamede de Carvalho
Published in: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Issue 19/1-2, 2017, Page(s) 155-156, ISSN 2167-8421
DOI: 10.1080/21678421.2017.1377735

Interplay of upper and lower motor neuron degeneration in amyotrophic lateral sclerosis

Author(s): Mamede de Carvalho, Artiom Poliakov, Cristiano Tavares, Michael Swash
Published in: Clinical Neurophysiology, Issue 128/11, 2017, Page(s) 2200-2204, ISSN 1388-2457
DOI: 10.1016/j.clinph.2017.08.024

International Survey of ALS Experts about Critical Questions for Assessing Patients with ALS

Author(s): Mamede De Carvalho, Adam Ryczkowski, Peter Andersen, Marta Gromicho, Julian Grosskreutz, Magdalena Kuźma-Kozakiewicz, Susanne Petri, Maria Piotrkiewicz, Gabriel Miltenberger Miltenyi
Published in: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Issue 18/7-8, 2017, Page(s) 505-510, ISSN 2167-8421
DOI: 10.1080/21678421.2017.1349150

Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies

Author(s): Hugo Vicente Miranda, Éva M. Szegő, Luís M. A. Oliveira, Carlo Breda, Ekrem Darendelioglu, Rita M. de Oliveira, Diana G. Ferreira, Marcos A. Gomes, Ruth Rott, Márcia Oliveira, Francesca Munari, Francisco J. Enguita, Tânia Simões, Eva F. Rodrigues, Michael Heinrich, Ivo C. Martins, Irina Zamolo, Olaf Riess, Carlos Cordeiro, Ana Ponces-Freire, Hilal A. Lashuel, Nuno C. Santos, Luisa V. Lopes,
Published in: Brain, Issue 140/5, 2017, Page(s) 1399-1419, ISSN 0006-8950
DOI: 10.1093/brain/awx056

α-synuclein interacts with PrPC to induce cognitive impairment through mGluR5 and NMDAR2B

Author(s): Diana G Ferreira, Mariana Temido-Ferreira, Hugo Vicente Miranda, Vânia L Batalha, Joana E Coelho, Éva M Szegö, Inês Marques-Morgado, Sandra H Vaz, Jeong Seop Rhee, Matthias Schmitz, Inga Zerr, Luísa V Lopes, Tiago F Outeiro
Published in: Nature Neuroscience, Issue 20/11, 2017, Page(s) 1569-1579, ISSN 1097-6256
DOI: 10.1038/nn.4648

Adenosine A 2A Receptors Modulate α-Synuclein Aggregation and Toxicity

Author(s): Diana G. Ferreira, Vânia L. Batalha, Hugo Vicente Miranda, Joana E. Coelho, Rui Gomes, Francisco Q. Gonçalves, Joana I. Real, José Rino, António Albino-Teixeira, Rodrigo A. Cunha, Tiago F. Outeiro, Luísa V. Lopes
Published in: Cerebral Cortex, 2017, Page(s) bhv268, ISSN 1047-3211
DOI: 10.1093/cercor/bhv268

Prolactin-induced neuroprotection against glutamate excitotoxicity is mediated by the reduction of [Ca2+]i overload and NF-κB activation

Author(s): Nadia A. Rivero-Segura, Edgar Flores-Soto, Selene García de la Cadena, Isabel Coronado-Mares, Juan C. Gomez-Verjan, Diana G. Ferreira, Erika Alejandra Cabrera-Reyes, Luísa V. Lopes, Lourdes Massieu, Marco Cerbón
Published in: PLOS ONE, Issue 12/5, 2017, Page(s) e0176910, ISSN 1932-6203
DOI: 10.1371/journal.pone.0176910

Mutant A53T α-Synuclein Improves Rotarod Performance Before Motor Deficits and Affects Metabolic Pathways

Author(s): Patrícia S. Guerreiro, Joana E. Coelho, Inês Sousa-Lima, Paula Macedo, Luísa V. Lopes, Tiago F. Outeiro, Teresa F. Pais
Published in: NeuroMolecular Medicine, Issue 19/1, 2017, Page(s) 113-121, ISSN 1535-1084
DOI: 10.1007/s12017-016-8435-5

Beneficial Effect of a Selective Adenosine A2A Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer’s Disease

Author(s): Emilie Faivre, Joana E. Coelho, Katja Zornbach, Enas Malik, Younis Baqi, Marion Schneider, Lucrezia Cellai, Kevin Carvalho, Shéhérazade Sebda, Martin Figeac, Sabiha Eddarkaoui, Raphaëlle Caillierez, Yijuang Chern, Michael Heneka, Nicolas Sergeant, Christa E. Müller, Annett Halle, Luc Buée, Luisa V. Lopes, David Blum
Published in: Frontiers in Molecular Neuroscience, Issue 11, 2018, ISSN 1662-5099
DOI: 10.3389/fnmol.2018.00235

Thrombolysis and thrombectomy in patients treated with dabigatran with acute ischemic stroke: Expert opinion

Author(s): HC Diener, R Bernstein, K Butcher, B Campbell, G Cloud, A Davalos, S Davis, JM Ferro, M Grond, D Krieger, G Ntaios, A Slowik, E Touzé
Published in: International Journal of Stroke, Issue 12/1, 2016, Page(s) 9-12, ISSN 1747-4930
DOI: 10.1177/1747493016669849

European Stroke Organization guideline for the diagnosis and treatment of cerebral venous thrombosis - endorsed by the European Academy of Neurology

Author(s): J. M. Ferro, M.-G. Bousser, P. Canhão, J. M. Coutinho, I. Crassard, F. Dentali, M. di Minno, A. Maino, I. Martinelli, F. Masuhr, D. Aguiar de Sousa, J. Stam
Published in: European Journal of Neurology, Issue 24/10, 2017, Page(s) 1203-1213, ISSN 1351-5101
DOI: 10.1111/ene.13381

Cerebral venous thrombosis

Author(s): Suzanne M. Silvis, Diana Aguiar de Sousa, José M. Ferro, Jonathan M Coutinho
Published in: Nature Reviews Neurology, Issue 13/9, 2017, Page(s) 555-565, ISSN 1759-4758
DOI: 10.1038/nrneurol.2017.104

Safety of Pregnancy After Cerebral Venous Thrombosis

Published in: ISSN 0039-2499
DOI: 10.1161/strokeaha.117.018829

Post-stroke seizures are clinically underestimated

Author(s): Carla Bentes, Hugo Martins, Ana Rita Peralta, Carlos Casimiro, Carlos Morgado, Ana Catarina Franco, Ana Catarina Fonseca, Ruth Geraldes, Patrícia Canhão, Teresa Pinho e Melo, Teresa Paiva, José M. Ferro
Published in: Journal of Neurology, Issue 264/9, 2017, Page(s) 1978-1985, ISSN 0340-5354
DOI: 10.1007/s00415-017-8586-9

Five-Year Risk of Stroke after TIA or Minor Ischemic Stroke

Author(s): Pierre Amarenco, Philippa C. Lavallée, Linsay Monteiro Tavares, Julien Labreuche, Gregory W. Albers, Halim Abboud, Sabrina Anticoli, Heinrich Audebert, Natan M. Bornstein, Louis R. Caplan, Manuel Correia, Geoffrey A. Donnan, José M. Ferro, Fernando Gongora-Rivera, Wolfgang Heide, Michael G. Hennerici, Peter J. Kelly, Michal Král, Hsiu-Fen Lin, Carlos Molina, Jong Moo Park, Francisco Purroy, Pet
Published in: New England Journal of Medicine, Issue 378/23, 2018, Page(s) 2182-2190, ISSN 0028-4793
DOI: 10.1056/nejmoa1802712

European Stroke Organization guideline for the diagnosis and treatment of cerebral venous thrombosis – Endorsed by the European Academy of Neurology

Author(s): José M Ferro, Marie-Germaine Bousser, Patrícia Canhão, Jonathan M Coutinho, Isabelle Crassard, Francesco Dentali, Matteo di Minno, Alberto Maino, Ida Martinelli, Florian Masuhr, Diana Aguiar de Sousa, Jan Stam
Published in: European Stroke Journal, Issue 2/3, 2017, Page(s) 195-221, ISSN 2396-9873
DOI: 10.1177/2396987317719364

Epileptic manifestations in stroke patients treated with intravenous alteplase

Author(s): C. Bentes, H. Martins, A. R. Peralta, C. Morgado, C. Casimiro, A. C. Franco, A. C. Fonseca, R. Geraldes, P. Canhão, T. Pinho e Melo, T. Paiva, J. M. Ferro
Published in: European Journal of Neurology, Issue 24/6, 2017, Page(s) 755-761, ISSN 1351-5101
DOI: 10.1111/ene.13292

Differences in Characteristics and Outcomes Between Asian and Non-Asian Patients in the TIAregistry.org

Published in: ISSN 0039-2499
DOI: 10.1161/strokeaha.117.016874

Symptomatic Patients Remain at Substantial Risk of Arterial Disease Complications Before and After Endarterectomy or Stenting

Published in: ISSN 0039-2499
DOI: 10.1161/strokeaha.116.015171

Patients With Undetermined Stroke Have Increased Atrial Fibrosis

Published in: ISSN 0039-2499
DOI: 10.1161/strokeaha.117.019641

Increase in the Admission of Stroke Mimics after Change in Emergency Shifts

Author(s): Mariana Vargas, Mariana Costa, Teresa Pinho e Melo, José M. Ferro, Ana Catarina Fonseca
Published in: Cerebrovascular Diseases, Issue 44/1-2, 2017, Page(s) 68-74, ISSN 1015-9770
DOI: 10.1159/000475823

Patent foramen ovale and stroke

Author(s): Bruno Miranda, Ana Catarina Fonseca, José M. Ferro
Published in: Journal of Neurology, Issue 265/8, 2018, Page(s) 1943-1949, ISSN 0340-5354
DOI: 10.1007/s00415-018-8865-0

Quantitative EEG and functional outcome following acute ischemic stroke

Author(s): Carla Bentes, Ana Rita Peralta, Pedro Viana, Hugo Martins, Carlos Morgado, Carlos Casimiro, Ana Catarina Franco, Ana Catarina Fonseca, Ruth Geraldes, Patrícia Canhão, Teresa Pinho e Melo, Teresa Paiva, José M. Ferro
Published in: Clinical Neurophysiology, Issue 129/8, 2018, Page(s) 1680-1687, ISSN 1388-2457
DOI: 10.1016/j.clinph.2018.05.021

Frequency of post-stroke electroencephalographic epileptiform activity – a systematic review and meta-analysis of observational studies

Author(s): Carla Bentes, Filipe B Rodrigues, Diana Sousa, Gonçalo S Duarte, Ana C Franco, Raquel Marques, Hipólito Nzwalo, Ana R Peralta, José M Ferro, João Costa
Published in: European Stroke Journal, Issue 2/4, 2017, Page(s) 361-368, ISSN 2396-9873
DOI: 10.1177/2396987317731004

Safety of pregnancy after cerebral venous thrombosis: systematic review update

Author(s): Diana Aguiar de Sousa, Patrícia Canhão, José M. Ferro
Published in: Journal of Neurology, Issue 265/1, 2018, Page(s) 211-212, ISSN 0340-5354
DOI: 10.1007/s00415-017-8666-x

Recanalization in Cerebral Venous Thrombosis

Published in: ISSN 0039-2499
DOI: 10.1161/strokeaha.118.022129

The impact of anger in adherence to treatment and beliefs about disease 1 year after stroke

Author(s): A. Catarina Santos, José M. Ferro
Published in: Journal of Neurology, Issue 264/9, 2017, Page(s) 1929-1938, ISSN 0340-5354
DOI: 10.1007/s00415-017-8577-x

Can We Predict Who Will Develop Hypertension After Carotid Endarterectomy?

Author(s): José M. Ferro
Published in: European Journal of Vascular and Endovascular Surgery, Issue 54/5, 2017, Page(s) 549-550, ISSN 1078-5884
DOI: 10.1016/j.ejvs.2017.09.001

Patients with undetermined ischemic stroke etiology show a high percentage of atrial tissue fibrosis

Author(s): A.C. Fonseca, P. Nascimento, T. Pinho e Melo, P. Canhão, J.M. Ferro, A.G. Almeida
Published in: Journal of the Neurological Sciences, Issue 381, 2017, Page(s) 504, ISSN 0022-510X
DOI: 10.1016/j.jns.2017.08.3628

Epilepsia partialis continua after an anterior circulation ischaemic stroke

Author(s): C. Bentes, A. C. Franco, A. R. Peralta, P. Viana, H. Martins, C. Morgado, C. Casimiro, C. Fonseca, R. Geraldes, P. Canhão, T. Pinho e Melo, T. Paiva, J. M. Ferro
Published in: European Journal of Neurology, Issue 24/7, 2017, Page(s) 929-934, ISSN 1351-5101
DOI: 10.1111/ene.13310

Validation of a Lower Back “Wearable”-Based Sit-to-Stand and Stand-to-Sit Algorithm for Patients With Parkinson's Disease and Older Adults in a Home-Like Environment

Author(s): Minh H. Pham, Elke Warmerdam, Morad Elshehabi, Christian Schlenstedt, Lu-Marie Bergeest, Maren Heller, Linda Haertner, Joaquim J. Ferreira, Daniela Berg, Gerhard Schmidt, Clint Hansen, Walter Maetzler
Published in: Frontiers in Neurology, Issue 9, 2018, ISSN 1664-2295
DOI: 10.3389/fneur.2018.00652

Opicapone for the management of end-of-dose motor fluctuations in patients with Parkinson’s disease treated with L-DOPA

Author(s): Andrew J. Lees, Joaquim Ferreira, Olivier Rascol, Heinz Reichmann, Fabrizio Stocchi, Eduardo Tolosa, Werner Poewe
Published in: Expert Review of Neurotherapeutics, Issue 17/7, 2017, Page(s) 649-659, ISSN 1473-7175
DOI: 10.1080/14737175.2017.1336086

Physician perception versus true efficacy of tetrabenazine for Huntington’s disease

Author(s): Filipe B. Rodrigues, Joaquim J. Ferreira, Edward J. Wild
Published in: Current Medical Research and Opinion, Issue 34/9, 2018, Page(s) 1537-1538, ISSN 0300-7995
DOI: 10.1080/03007995.2018.1490703

Quality and reporting of guidelines on the diagnosis and management of dystonia

Author(s): G. Tamás, C. Abrantes, A. Valadas, P. Radics, A. Albanese, M. A. J. Tijssen, J. J. Ferreira
Published in: European Journal of Neurology, Issue 25/2, 2018, Page(s) 275-283, ISSN 1351-5101
DOI: 10.1111/ene.13488

Erratum - Information Sources and Decision-Making in Neurosurgery: Results of a Survey of Members of the Brazilian Neurosurgery Society

Author(s): Rodrigo Gorayeb, Maria Forjaz, Antônio Gonçalves-Ferreira, Joaquim Ferreira
Published in: Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery, Issue 37/02, 2018, Page(s) 162-162, ISSN 0103-5355
DOI: 10.1055/s-0038-1667058

Information Sources and Decision-Making in Neurosurgery: Results of a Survey of Members of the Brazilian Neurosurgery Society

Author(s): Rodrigo Gorayeb, Maria João Forjaz, Antônio Gonçalves-Ferreira, Joaquim Ferreira
Published in: Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery, Issue 37/02, 2018, Page(s) 081-087, ISSN 0103-5355
DOI: 10.1055/s-0038-1656716

Psychosocial impact of Parkinson's disease-associated dysarthria: Cross-cultural adaptation and validation of the Dysarthria Impact Profile into European Portuguese

Published in: ISSN 1444-1586
DOI: 10.1111/ggi.13255

Comments on: ‘Pyridostigmine bromide versus fludrocortisone in the treatment of orthostatic hypotension in Parkinson's disease - a randomized controlled trial’

Author(s): R. M. Simões, A. Castro Caldas, J. J. Ferreira
Published in: European Journal of Neurology, Issue 25/1, 2018, Page(s) e4-e4, ISSN 1351-5101
DOI: 10.1111/ene.13475

Suspected adverse drug reaction reports with oral anticoagulants in Portugal: a pharmacovigilance study

Author(s): Daniel Caldeira, Raquel Rodrigues, Daisy Abreu, Ana Marta Anes, Mário M. Rosa, Joaquim J. Ferreira
Published in: Expert Opinion on Drug Safety, Issue 17/4, 2018, Page(s) 339-345, ISSN 1474-0338
DOI: 10.1080/14740338.2018.1439474

The launch of opicapone for Parkinson’s disease: negatives versus positives

Author(s): Ana Castro Caldas, Tiago Teodoro, Joaquim J Ferreira
Published in: Expert Opinion on Drug Safety, Issue 17/3, 2018, Page(s) 331-337, ISSN 1474-0338
DOI: 10.1080/14740338.2018.1433659

Mitochondrial quality control pathways: PINK1 acts as a gatekeeper

Author(s): Elvira P. Leites, Vanessa A. Morais
Published in: Biochemical and Biophysical Research Communications, Issue 500/1, 2018, Page(s) 45-50, ISSN 0006-291X
DOI: 10.1016/j.bbrc.2017.06.096

β-Amyloid Precursor Protein Intracellular Domain Controls Mitochondrial Function by Modulating Phosphatase and Tensin Homolog–Induced Kinase 1 Transcription in Cells and in Alzheimer Mice Models

Author(s): Thomas Goiran, Eric Duplan, Mounia Chami, Alexandre Bourgeois, Wejdane El Manaa, Lila Rouland, Julie Dunys, Inger Lauritzen, Han You, Vuk Stambolic, Maria-Grazia Biféri, Martine Barkats, Sanjay W. Pimplikar, Nicolas Sergeant, Morvane Colin, Vanessa A. Morais, Raphaelle Pardossi-Piquard, Frédéric Checler, Cristine Alves da Costa
Published in: Biological Psychiatry, Issue 83/5, 2018, Page(s) 416-427, ISSN 0006-3223
DOI: 10.1016/j.biopsych.2017.04.011

Cardiolipin promotes electron transport between ubiquinone and complex I to rescue PINK1 deficiency

Author(s): Melissa Vos, Ann Geens, Claudia Böhm, Liesbeth Deaulmerie, Jef Swerts, Matteo Rossi, Katleen Craessaerts, Elvira P. Leites, Philip Seibler, Aleksandar Rakovic, Thora Lohnau, Bart De Strooper, Sarah-Maria Fendt, Vanessa A. Morais, Christine Klein, Patrik Verstreken
Published in: The Journal of Cell Biology, Issue 216/3, 2017, Page(s) 695-708, ISSN 0021-9525
DOI: 10.1083/jcb.201511044

Chronic, intermittent treatment with a cannabinoid receptor agonist impairs recognition memory and brain network functional connectivity

Author(s): Francisco M. Mouro, Joaquim A. Ribeiro, Ana M. Sebastião, Neil Dawson
Published in: Journal of Neurochemistry, Issue 147/1, 2018, Page(s) 71-83, ISSN 0022-3042
DOI: 10.1111/jnc.14549

Amyotrophic Lateral Sclerosis (ALS) and Adenosine Receptors

Author(s): Ana M. Sebastião, Nádia Rei, Joaquim A. Ribeiro
Published in: Frontiers in Pharmacology, Issue 9, 2018, ISSN 1663-9812
DOI: 10.3389/fphar.2018.00267

Autophagy induction impairs Wnt/β-catenin signalling through β-catenin relocalisation in glioblastoma cells

Author(s): Barbara Colella, Fiorella Faienza, Marianna Carinci, Giuseppina D'Alessandro, Myriam Catalano, Antonio Santoro, Francesco Cecconi, Cristina Limatola, Sabrina Di Bartolomeo
Published in: Cellular Signalling, Issue 53, 2019, Page(s) 357-364, ISSN 0898-6568
DOI: 10.1016/j.cellsig.2018.10.017

Kv1.3 activity perturbs the homeostatic properties of astrocytes in glioma

Author(s): Alfonso Grimaldi, Giuseppina D’Alessandro, Maria Amalia Di Castro, Clotilde Lauro, Vikrant Singh, Francesca Pagani, Luigi Sforna, Francesca Grassi, Silvia Di Angelantonio, Luigi Catacuzzeno, Heike Wulff, Cristina Limatola, Myriam Catalano
Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
DOI: 10.1038/s41598-018-25940-5

Decreased plasma C-reactive protein levels in APOE ε 4 allele carriers

Author(s): Henna Martiskainen, Mari Takalo, Alina Solomon, Alena Stančáková, Mikael Marttinen, Teemu Natunen, Annakaisa Haapasalo, Sanna-Kaisa Herukka, Johanna Kuusisto, Hilkka Soininen, Miia Kivipelto, Markku Laakso, Mikko Hiltunen
Published in: Annals of Clinical and Translational Neurology, Issue 5/10, 2018, Page(s) 1229-1240, ISSN 2328-9503
DOI: 10.1002/acn3.639

CXCL16/CXCR6 Axis Drives Microglia/Macrophages Phenotype in Physiological Conditions and Plays a Crucial Role in Glioma

Author(s): Francesca Lepore, Giuseppina D'Alessandro, Fabrizio Antonangeli, Antonio Santoro, Vincenzo Esposito, Cristina Limatola, Flavia Trettel
Published in: Frontiers in Immunology, Issue 9, 2018, ISSN 1664-3224
DOI: 10.3389/fimmu.2018.02750

Inflammation, neurodegeneration and protein aggregation in the retina as ocular biomarkers for Alzheimer’s disease in the 3xTg-AD mouse model

Published in: ISSN 2041-4889
DOI: 10.1038/s41419-018-0740-5

Ca2+-activated K+ channels modulate microglia affecting motor neuron survival in hSOD1G93A mice

Author(s): Germana Cocozza, Maria Amalia di Castro, Laura Carbonari, Alfonso Grimaldi, Fabrizio Antonangeli, Stefano Garofalo, Alessandra Porzia, Michele Madonna, Fabrizio Mainiero, Angela Santoni, Francesca Grassi, Heike Wulff, Giuseppina D'Alessandro, Cristina Limatola
Published in: Brain, Behavior, and Immunity, Issue 73, 2018, Page(s) 584-595, ISSN 0889-1591
DOI: 10.1016/j.bbi.2018.07.002

TrkB-ICD Fragment, Originating From BDNF Receptor Cleavage, Is Translocated to Cell Nucleus and Phosphorylates Nuclear and Axonal Proteins

Author(s): João Fonseca-Gomes, André Jerónimo-Santos, Angelina Lesnikova, Plinio Casarotto, Eero Castrén, Ana M. Sebastião, Maria J. Diógenes
Published in: Frontiers in Molecular Neuroscience, Issue 12, 2019, ISSN 1662-5099
DOI: 10.3389/fnmol.2019.00004

Intranasal insulin activates Akt2 signaling pathway in the hippocampus of wild-type but not in APP/PS1 Alzheimer model mice

Author(s): Sami Gabbouj, Teemu Natunen, Hennariikka Koivisto, Kimmo Jokivarsi, Mari Takalo, Mikael Marttinen, Rebekka Wittrahm, Susanna Kemppainen, Reyhaneh Naderi, Adrián Posado-Fernández, Simo Ryhänen, Petra Mäkinen, Kaisa M.A. Paldanius, Gonçalo Doria, Pekka Poutiainen, Orfeu Flores, Annakaisa Haapasalo, Heikki Tanila, Mikko Hiltunen
Published in: Neurobiology of Aging, Issue 75, 2019, Page(s) 98-108, ISSN 0197-4580
DOI: 10.1016/j.neurobiolaging.2018.11.008

A multiomic approach to characterize the temporal sequence in Alzheimer's disease-related pathology

Author(s): Mikael Marttinen, Jussi Paananen, Antonio Neme, Vikram Mitra, Mari Takalo, Teemu Natunen, Kaisa M.A. Paldanius, Petra Mäkinen, Michael Bremang, Mitja I. Kurki, Tuomas Rauramaa, Ville Leinonen, Hilkka Soininen, Annakaisa Haapasalo, Ian Pike, Mikko Hiltunen
Published in: Neurobiology of Disease, Issue 124, 2019, Page(s) 454-468, ISSN 0969-9961
DOI: 10.1016/j.nbd.2018.12.009

Adenosine A 2A receptors facilitate synaptic NMDA currents in CA1 pyramidal neurons

Author(s): Francisco M Mouro, Diogo M Rombo, Raquel B Dias, Joaquim A Ribeiro, Ana M Sebastião
Published in: British Journal of Pharmacology, Issue 175/23, 2018, Page(s) 4386-4397, ISSN 0007-1188
DOI: 10.1111/bph.14497

Brain-Derived Neurotrophic Factor (BDNF) Role in Cannabinoid-Mediated Neurogenesis

Author(s): Filipa Fiel Ferreira, Filipa F. Ribeiro, Rui S. Rodrigues, Ana Maria Sebastião, Sara Xapelli
Published in: Frontiers in Cellular Neuroscience, Issue 12, 2018, ISSN 1662-5102
DOI: 10.3389/fncel.2018.00441

Anxiety Assessment in Pre-clinical Tests and in Clinical Trials: A Critical Review

Author(s): Lígia Castanheira, Miguel F. Ferreira, Ana M. Sebastião, Diogo Telles-Correia
Published in: Current Topics in Medicinal Chemistry, Issue 18/19, 2018, Page(s) 1656-1676, ISSN 1568-0266
DOI: 10.2174/1568026618666181115102518

Depression Assessment in Clinical Trials and Pre-clinical Tests: A Critical Review

Author(s): Miguel F. Ferreira, Lígia Castanheira, Ana M. Sebastião, Diogo Telles-Correia
Published in: Current Topics in Medicinal Chemistry, Issue 18/19, 2018, Page(s) 1677-1703, ISSN 1568-0266
DOI: 10.2174/1568026618666181115095920

Hippocampal GABAergic transmission: a new target for adenosine control of excitability

Author(s): Diogo M. Rombo, Joaquim A. Ribeiro, Ana M. Sebastião
Published in: Journal of Neurochemistry, Issue 139/6, 2016, Page(s) 1056-1070, ISSN 0022-3042
DOI: 10.1111/jnc.13872

Rare Variants in PLD3 Do Not Affect Risk for Early-Onset Alzheimer Disease in a European Consortium Cohort

Published in: ISSN 1059-7794
DOI: 10.1002/humu.22908

BDNF, via truncated TrkB receptor, modulates GlyT1 and GlyT2 in astrocytes

Published in: ISSN 0894-1491
DOI: 10.1002/glia.22884

Adenosine A2A receptor activation is determinant for BDNF actions upon GABA and glutamate release from rat hippocampal synaptosomes

Author(s): Sandra Henriques Vaz, Sofia Rapaz Lérias, Sara Parreira, Maria José Diógenes, Ana Maria Sebastião
Published in: Purinergic Signalling, Issue 11/4, 2015, Page(s) 607-612, ISSN 1573-9538
DOI: 10.1007/s11302-015-9476-1

Do We Have a Channel Solution for ALS?

Author(s): Mamede de Carvalho
Published in: EBioMedicine, Issue 2/12, 2015, Page(s) 1842-1843, ISSN 2352-3964
DOI: 10.1016/j.ebiom.2015.12.002

Tracking motor neuron loss in a set of six muscles in amyotrophic lateral sclerosis using the Motor Unit Number Index (MUNIX): a 15-month longitudinal multicentre trial

Published in: ISSN 0022-3050
DOI: 10.1136/jnnp-2015-310509

Presymptomatic and symptomatic ALS SOD1(G93A) mice differ in adenosine A1 and A2A receptor-mediated tonic modulation of neuromuscular transmission

Author(s): Filipe Nascimento, Ana M. Sebastião, Joaquim A. Ribeiro
Published in: Purinergic Signalling, Issue 11/4, 2015, Page(s) 471-480, ISSN 1573-9538
DOI: 10.1007/s11302-015-9465-4

Neuromodulation and metamodulation by adenosine: Impact and subtleties upon synaptic plasticity regulation

Author(s): Ana M. Sebastião, Joaquim A. Ribeiro
Published in: Brain Research, Issue 1621, 2015, Page(s) 102-113, ISSN 0006-8993
DOI: 10.1016/j.brainres.2014.11.008

Prognostic models based on patient snapshots and time windows: Predicting disease progression to assisted ventilation in Amyotrophic Lateral Sclerosis

Author(s): André V. Carreiro, Pedro M.T. Amaral, Susana Pinto, Pedro Tomás, Mamede de Carvalho, Sara C. Madeira
Published in: Journal of Biomedical Informatics, Issue 58, 2015, Page(s) 133-144, ISSN 1532-0464
DOI: 10.1016/j.jbi.2015.09.021

Brain-derived neurotrophic factor mediates neuroprotection against A β -induced toxicity through a mechanism independent on adenosine 2A receptor activation

Published in: ISSN 0897-7194
DOI: 10.3109/08977194.2015.1080696

Integrative biomarker discovery in neurodegenerative diseases

Author(s): André V. Carreiro, Alexandre Mendonça, Mamede de Carvalho, Sara C. Madeira
Published in: Wiley Interdisciplinary Reviews: Systems Biology and Medicine, Issue 7/6, 2015, Page(s) 357-379, ISSN 1939-5094
DOI: 10.1002/wsbm.1310

Decrease in APP and CP mRNA expression supports impairment of iron export in Alzheimer's disease patients

Author(s): Cláudia Guerreiro, Bruno Silva, Ângela C. Crespo, Liliana Marques, Sónia Costa, Ângela Timóteo, Erica Marcelino, Carolina Maruta, Arminda Vilares, Mafalda Matos, Frederico Simões Couto, Paula Faustino, Ana Verdelho, Manuela Guerreiro, Ana Herrero, Cristina Costa, Alexandre de Mendonça, Madalena Martins, Luciana Costa
Published in: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Issue 1852/10, 2015, Page(s) 2116-2122, ISSN 0925-4439
DOI: 10.1016/j.bbadis.2015.07.017

Purine nucleosides in neuroregeneration and neuroprotection

Author(s): Filipa F. Ribeiro, Sara Xapelli, Catarina Miranda-Lourenço, Sara R. Tanqueiro, João Fonseca-Gomes, Maria J. Diógenes, Joaquim A. Ribeiro, Ana M. Sebastião
Published in: Neuropharmacology, 2015, ISSN 0028-3908
DOI: 10.1016/j.neuropharm.2015.11.006

Neural commitment of human pluripotent stem cells under defined conditions recapitulates neural development and generates patient-specific neural cells

Published in: ISSN 1860-6768
DOI: 10.1002/biot.201400751

Adenosine A2A Receptors Modulate α-Synuclein Aggregation and Toxicity

Author(s): Ferreira DG, Batalha VL, Vicente Miranda H, Coelho JE, Gomes R, Gonçalves FQ, Real JI, Rino J, Albino-Teixeira A, Cunha RA, Outeiro TF, Lopes LV
Published in: Cereb Cortex. 2015 Nov 2. pii: bhv268, 2015, ISSN 1460-2199

Dysregulation of TrkB Receptors and BDNF Function by Amyloid-β Peptide is Mediated by Calpain

Author(s): André Jerónimo-Santos, Sandra Henriques Vaz, Sara Parreira, Sofia Rapaz-Lérias, António P. Caetano, Valérie Buée-Scherrer, Eero Castrén, Claudia A. Valente, David Blum, Ana Maria Sebastião, Maria José Diógenes
Published in: Cerebral Cortex, Issue 25/9, 2015, Page(s) 3107-3121, ISSN 1047-3211
DOI: 10.1093/cercor/bhu105

Axonal elongation and dendritic branching is enhanced by adenosine A2A receptors activation in cerebral cortical neurons

Author(s): Ribeiro FF, Neves-Tomé R, Assaife-Lopes N, Santos TE, Silva RF, Brites D, Ribeiro JA, Sousa MM, Sebastião AM.
Published in: Brain Struct Funct. 2015 Jun 12, 2015, ISSN 1863-2661

Predicting clinical response in people at ultra-high risk of psychosis: a systematic and quantitative review

Author(s): Andrea Mechelli, Diana Prata, Charles Kefford, Shitij Kapur
Published in: Drug Discovery Today, Issue 20/8, 2015, Page(s) 924-927, ISSN 1359-6446
DOI: 10.1016/j.drudis.2015.03.003

Comment on: The Awaji criteria are not always superior to the previous criteria: A meta-analysis

Published in: ISSN 0148-639X
DOI: 10.1002/mus.24734

Ensuring continued progress in biomarkers for amyotrophic lateral sclerosis: Another view

Published in: ISSN 0148-639X
DOI: 10.1002/mus.24517

The R of ALSFRS-R: Does it really mirror functional respiratory involvement in amyotrophic lateral sclerosis?

Author(s): Susana Pinto, Mamede de Carvalho
Published in: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Issue 16/1-2, 2014, Page(s) 120-123, ISSN 2167-8421
DOI: 10.3109/21678421.2014.952641

The giant miniature endplate potentials frequency is increased in aged rats

Author(s): Paula A. Pousinha, Alexandra M. Correia, Ana M. Sebastião, Joaquim A. Ribeiro
Published in: Neuroscience Letters, Issue 584, 2015, Page(s) 224-229, ISSN 0304-3940
DOI: 10.1016/j.neulet.2014.10.035

Tackling diagnostic delays in ALS

Author(s): Mamede de Carvalho
Published in: The Lancet Neurology, Issue 14/5, 2015, Page(s) 457-458, ISSN 1474-4422
DOI: 10.1016/S1474-4422(15)00020-4

Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia

Author(s): Axel Freischmidt, Thomas Wieland, Benjamin Richter, Wolfgang Ruf, Veronique Schaeffer, Kathrin Müller, Nicolai Marroquin, Frida Nordin, Annemarie Hübers, Patrick Weydt, Susana Pinto, Rayomond Press, Stéphanie Millecamps, Nicolas Molko, Emilien Bernard, Claude Desnuelle, Marie-Hélène Soriani, Johannes Dorst, Elisabeth Graf, Ulrika Nordström, Marisa S Feiler, Stefan Putz, Tobias M Boeckers, Th
Published in: Nature Neuroscience, Issue 18/5, 2015, Page(s) 631-636, ISSN 1097-6256
DOI: 10.1038/nn.4000

Changes in corticostriatal connectivity during reinforcement learning in humans

Published in: ISSN 1065-9471
DOI: 10.1002/hbm.22665

MicroRNA-34a Modulates Neural Stem Cell Differentiation by Regulating Expression of Synaptic and Autophagic Proteins

Author(s): Ana L. Morgado, Joana M. Xavier, Pedro A. Dionísio, Maria F. C. Ribeiro, Raquel B. Dias, Ana M. Sebastião, Susana Solá, Cecília M. P. Rodrigues
Published in: Molecular Neurobiology, Issue 51/3, 2015, Page(s) 1168-1183, ISSN 0893-7648
DOI: 10.1007/s12035-014-8794-6

Synaptic mechanisms of adenosine A 2A receptor-mediated hyperexcitability in the hippocampus

Published in: ISSN 1050-9631
DOI: 10.1002/hipo.22392

The Combined Inhibitory Effect of the Adenosine A 1 and Cannabinoid CB 1 Receptors on cAMP Accumulation in the Hippocampus Is Additive and Independent of A 1 Receptor Desensitization

Author(s): André Serpa, Sara Correia, Joaquim A. Ribeiro, Ana M. Sebastião, José F. Cascalheira
Published in: BioMed Research International, Issue 2015, 2015, Page(s) 1-9, ISSN 2314-6133
DOI: 10.1155/2015/872684

Non-literal language deficits in mild cognitive impairment

Author(s): Sandra Cardoso, Dina Silva, João Maroco, Alexandre de Mendonça, Manuela Guerreiro
Published in: Psychogeriatrics, Issue 14/4, 2014, Page(s) 222-228, ISSN 1346-3500
DOI: 10.1111/psyg.12101

Neuroinflammation after neonatal hypoxia–ischemia is associated with alterations in the purinergic system: adenosine deaminase 1 isoenzyme is the most predominant after insult

Author(s): Victor Camera Pimentel, Maria Beatriz Moretto, Mariana Colino Oliveira, Daniela Zanini, Ana Maria Sebastião, Maria Rosa Chitolina Schetinger
Published in: Molecular and Cellular Biochemistry, Issue 403/1-2, 2015, Page(s) 169-177, ISSN 0300-8177
DOI: 10.1007/s11010-015-2347-9

Genetic variability in SQSTM1 and risk of early-onset Alzheimer dementia: a European early-onset dementia consortium study

Author(s): Elise Cuyvers, Julie van der Zee, Karolien Bettens, Sebastiaan Engelborghs, Mathieu Vandenbulcke, Caroline Robberecht, Lubina Dillen, Céline Merlin, Nathalie Geerts, Caroline Graff, Håkan Thonberg, Huei-Hsin Chiang, Pau Pastor, Sara Ortega-Cubero, Maria A. Pastor, Janine Diehl-Schmid, Panagiotis Alexopoulos, Luisa Benussi, Roberta Ghidoni, Giuliano Binetti, Benedetta Nacmias, Sandro Sorbi, Raque
Published in: Neurobiology of Aging, Issue 36/5, 2015, Page(s) 2005.e15-2005.e22, ISSN 0197-4580
DOI: 10.1016/j.neurobiolaging.2015.02.014

Prevalence and prognosis of Alzheimer’s disease at the mild cognitive impairment stage

Author(s): Stephanie J. B. Vos, Frans Verhey, Lutz Frölich, Johannes Kornhuber, Jens Wiltfang, Wolfgang Maier, Oliver Peters, Eckart Rüther, Flavio Nobili, Silvia Morbelli, Giovanni B. Frisoni, Alexander Drzezga, Mira Didic, Bart N. M. van Berckel, Andrew Simmons, Hilkka Soininen, Iwona Kłoszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas, Simon Lovestone, Cristina Muscio, Sanna-Kaisa Herukka, Eric S
Published in: Brain, Issue 138/5, 2015, Page(s) 1327-1338, ISSN 0006-8950
DOI: 10.1093/brain/awv029

Phosphoneurofilament heavy chain and N-glycomics from the cerebrospinal fluid in amyotrophic lateral sclerosis

Author(s): Margarida Gonçalves, Linda Tillack, Mamede de Carvalho, Susana Pinto, Harald S. Conradt, Júlia Costa
Published in: Clinica Chimica Acta, Issue 438, 2015, Page(s) 342-349, ISSN 0009-8981
DOI: 10.1016/j.cca.2014.09.011

Ultrasound in ALS: Is it a sound method?

Author(s): Mamede de Carvalho
Published in: Clinical Neurophysiology, Issue 126/4, 2015, Page(s) 651-652, ISSN 1388-2457
DOI: 10.1016/j.clinph.2014.08.002

Differential Role of the Proteasome in the Early and Late Phases of BDNF-Induced Facilitation of LTP

Author(s): A. R. Santos, M. Mele, S. H. Vaz, B. Kellermayer, M. Grimaldi, M. Colino-Oliveira, D. M. Rombo, D. Comprido, A. M. Sebastiao, C. B. Duarte
Published in: Journal of Neuroscience, Issue 35/8, 2015, Page(s) 3319-3329, ISSN 0270-6474
DOI: 10.1523/JNEUROSCI.4521-14.2015

Classification of primary progressive aphasia: Do unsupervised data mining methods support a logopenic variant?

Author(s): Carolina Maruta, Telma Pereira, Sara C. Madeira, Alexandre De Mendonça, Manuela Guerreiro
Published in: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Issue 16/3-4, 2015, Page(s) 147-159, ISSN 2167-8421
DOI: 10.3109/21678421.2015.1026266

The use of biomarkers for the etiologic diagnosis of MCI in Europe: An EADC survey

Published in: ISSN 1552-5260
DOI: 10.1016/j.jalz.2014.06.006

Significance of Subjective Memory Complaints in the Clinical Setting

Author(s): D. Silva, M. Guerreiro, C. Faria, J. Maroco, B. A. Schmand, A. d. Mendonca
Published in: Journal of Geriatric Psychiatry and Neurology, Issue 27/4, 2014, Page(s) 259-265, ISSN 0891-9887
DOI: 10.1177/0891988714532018

Modulation of cGMP accumulation by adenosine A1 receptors at the hippocampus: Influence of cGMP levels and gender

Author(s): André Serpa, Ana M. Sebastião, José F. Cascalheira
Published in: European Journal of Pharmacology, Issue 744, 2014, Page(s) 83-90, ISSN 0014-2999
DOI: 10.1016/j.ejphar.2014.09.045

Endogenous inhibition of hippocampal LTD and depotentiation by vasoactive intestinal peptide VPAC 1 receptors

Published in: ISSN 1050-9631
DOI: 10.1002/hipo.22316

Young slow-progressing ALS patients are at higher risk of inappropriate and disease-quickening surgeries

Author(s): Susana Pinto, Mamede de Carvalho
Published in: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Issue 15/7-8, 2014, Page(s) 621-621, ISSN 2167-8421
DOI: 10.3109/21678421.2014.948881

Maternal separation impairs long term-potentiation in CA1-CA3 synapses and hippocampal-dependent memory in old rats

Author(s): Vasco C. Sousa, Joana Vital, Ana Rita Costenla, Vânia L. Batalha, Ana M. Sebastião, Joaquim A. Ribeiro, Luísa V. Lopes
Published in: Neurobiology of Aging, Issue 35/7, 2014, Page(s) 1680-1685, ISSN 0197-4580
DOI: 10.1016/j.neurobiolaging.2014.01.024

Does surgery accelerate progression of amyotrophic lateral sclerosis?

Published in: ISSN 0022-3050
DOI: 10.1136/jnnp-2013-305770

Adenosine A2A Receptors Activation Facilitates Neuromuscular Transmission in the Pre-Symptomatic Phase of the SOD1(G93A) ALS Mice, but Not in the Symptomatic Phase

Author(s): Filipe Nascimento, Paula A. Pousinha, Alexandra M. Correia, Rui Gomes, Ana M. Sebastião, Joaquim A. Ribeiro
Published in: PLoS ONE, Issue 9/8, 2014, Page(s) e104081, ISSN 1932-6203
DOI: 10.1371/journal.pone.0104081

Impact of in vivo chronic blockade of adenosine A2A receptors on the BDNF-mediated facilitation of LTP

Author(s): André Jerónimo-Santos, Vânia L. Batalha, Christa E. Müller, Younis Baqi, Ana Maria Sebastião, Luisa V. Lopes, Maria José Diógenes
Published in: Neuropharmacology, Issue 83, 2014, Page(s) 99-106, ISSN 0028-3908
DOI: 10.1016/j.neuropharm.2014.04.006

Mechanisms of Regulation of Olfactory Transduction and Adaptation in the Olfactory Cilium

Author(s): Gabriela Antunes, Ana Maria Sebastião, Fabio Marques Simoes de Souza
Published in: PLoS ONE, Issue 9/8, 2014, Page(s) e105531, ISSN 1932-6203
DOI: 10.1371/journal.pone.0105531

Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration

Author(s): Julie van der Zee, Tim Van Langenhove, Gabor G. Kovacs, Lubina Dillen, William Deschamps, Sebastiaan Engelborghs, Radoslav Matěj, Mathieu Vandenbulcke, Anne Sieben, Bart Dermaut, Katrien Smets, Philip Van Damme, Céline Merlin, Annelies Laureys, Marleen Van Den Broeck, Maria Mattheijssens, Karin Peeters, Luisa Benussi, Giuliano Binetti, Roberta Ghidoni, Barbara Borroni, Alessandro Padovani, Silva
Published in: Acta Neuropathologica, Issue 128/3, 2014, Page(s) 397-410, ISSN 0001-6322
DOI: 10.1007/s00401-014-1298-7

Overexpression of Adenosine A2A Receptors in Rats: Effects on Depression, Locomotion, and Anxiety

Author(s): Joana E. Coelho, Pedro Alves, Paula M. Canas, Jorge S. Valadas, Tatiana Shmidt, VÃ¢nia L. Batalha, Diana G. Ferreira, Joaquim A. Ribeiro, Michael Bader, Rodrigo A. Cunha, Frederico SimÃµes do Couto, LuÃsa V. Lopes
Published in: Frontiers in Psychiatry, Issue 5, 2014, ISSN 1664-0640
DOI: 10.3389/fpsyt.2014.00067

P2Y 1 receptor inhibits GABA transport through a calcium signalling-dependent mechanism in rat cortical astrocytes

Published in: ISSN 0894-1491
DOI: 10.1002/glia.22673

Delayed diagnosis in ALS: The problem continues

Author(s): Hipolito Nzwalo, Daisy de Abreu, Michael Swash, Susana Pinto, Mamede de Carvalho
Published in: Journal of the Neurological Sciences, Issue 343/1-2, 2014, Page(s) 173-175, ISSN 0022-510X
DOI: 10.1016/j.jns.2014.06.003

Multicentre quality control evaluation of different biomarker candidates for amyotrophic lateral sclerosis

Author(s): Stefan Lehnert, Julia Costa, Mamede de Carvalho, Janine Kirby, Magdalena Kuzma-Kozakiewicz, Claudia Morelli, Wim Robberecht, Pamela Shaw, Vincenzo Silani, Petra Steinacker, Hayrettin Tumani, Philip Van Damme, Albert Ludolph, Markus Otto
Published in: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Issue 15/5-6, 2014, Page(s) 344-350, ISSN 2167-8421
DOI: 10.3109/21678421.2014.884592

Modeling the functional network of primary intercellular Ca2+ wave propagation in astrocytes and its application to study drug effects

Author(s): Marcelo Pires, Frank Raischel, Sandra H. Vaz, Andreia Cruz-Silva, Ana M. Sebastião, Pedro G. Lind
Published in: Journal of Theoretical Biology, Issue 356, 2014, Page(s) 201-212, ISSN 0022-5193
DOI: 10.1016/j.jtbi.2014.04.024

Motoneuron firing in amyotrophic lateral sclerosis (ALS)

Author(s): Mamede de Carvalho, Andrew Eisen, Charles Krieger, Michael Swash
Published in: Frontiers in Human Neuroscience, Issue 8, 2014, ISSN 1662-5161
DOI: 10.3389/fnhum.2014.00719

Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS)

Author(s): Jean-Pascal Lefaucheur, Nathalie André-Obadia, Andrea Antal, Samar S. Ayache, Chris Baeken, David H. Benninger, Roberto M. Cantello, Massimo Cincotta, Mamede de Carvalho, Dirk De Ridder, Hervé Devanne, Vincenzo Di Lazzaro, Saša R. Filipović, Friedhelm C. Hummel, Satu K. Jääskeläinen, Vasilios K. Kimiskidis, Giacomo Koch, Berthold Langguth, Thomas Nyffeler, Antonio Oliviero, Frank Padberg, E
Published in: Clinical Neurophysiology, Issue 125/11, 2014, Page(s) 2150-2206, ISSN 1388-2457
DOI: 10.1016/j.clinph.2014.05.021

Neurophysiological techniques to detect early small-fiber dysfunction in transthyretin amyloid polyneuropathy

Published in: ISSN 0148-639X
DOI: 10.1002/mus.23901

Challenges and Promises in the Development of Neurotrophic Factor-Based Therapies for Parkinson’s Disease

Published in: ISSN 1170-229X
DOI: 10.1007/s40266-014-0160-x

Sensitivity of MUP parameters in detecting change in early ALS

Author(s): Mamede de Carvalho, Antonia Turkman, Michael Swash
Published in: Clinical Neurophysiology, Issue 125/1, 2014, Page(s) 166-169, ISSN 1388-2457
DOI: 10.1016/j.clinph.2013.06.014

A handful of promises

Author(s): Mamede de Carvalho
Published in: Clinical Neurophysiology, Issue 125/1, 2014, Page(s) 5, ISSN 1388-2457
DOI: 10.1016/j.clinph.2013.08.011

Homeostatic Control of Synaptic Activity by Endogenous Adenosine is Mediated by Adenosine Kinase

Author(s): M. J. Diogenes, R. Neves-Tome, S. Fucile, K. Martinello, M. Scianni, P. Theofilas, J. Lopatar, J. A. Ribeiro, L. Maggi, B. G. Frenguelli, C. Limatola, D. Boison, A. M. Sebastiao
Published in: Cerebral Cortex, Issue 24/1, 2013, Page(s) 67-80, ISSN 1047-3211
DOI: 10.1093/cercor/bhs284

Breathing new life into treatment advances for respiratory failure in amyotrophic lateral sclerosis patients

Author(s): Susana Pinto, Mamede de Carvalho
Published in: Neurodegenerative Disease Management, Issue 4/1, 2014, Page(s) 83-102, ISSN 1758-2024
DOI: 10.2217/nmt.13.74

From epidemiology to pathophysiology: what about caffeine in Alzheimer's disease?

Author(s): Vanessa Flaten, Cyril Laurent, Joana E. Coelho, Ursula Sandau, Vânia L. Batalha, Sylvie Burnouf, Malika Hamdane, Sandrine Humez, Detlev Boison, Luísa V. Lopes, Luc Buée, David Blum
Published in: Biochemical Society Transactions, Issue 42/2, 2014, Page(s) 587-592, ISSN 0300-5127
DOI: 10.1042/BST20130229

Modulation of subventricular zone oligodendrogenesis: a role for hemopressin?

Author(s): Sara Xapelli, Fabienne Agasse, Sofia Grade, Liliana Bernardino, Filipa F. Ribeiro, Clarissa S. Schitine, Andrea S. Heimann, Emer S. Ferro, Ana M. Sebasti, Ricardo A. De Melo Reis, João O. Malva
Published in: Frontiers in Cellular Neuroscience, Issue 8, 2014, ISSN 1662-5102
DOI: 10.3389/fncel.2014.00059

Roles of Vascular Endothelial Growth Factor in Amyotrophic Lateral Sclerosis

Author(s): Ana Catarina Pronto-Laborinho, Susana Pinto, Mamede de Carvalho
Published in: BioMed Research International, Issue 2014, 2014, Page(s) 1-24, ISSN 2314-6133
DOI: 10.1155/2014/947513

A blinded international study on the reliability of genetic testing for GGGGCC-repeat expansions in C9orf72 reveals marked differences in results among 14 laboratories

Author(s): C. Akimoto, A. E. Volk, M. van Blitterswijk, M. Van den Broeck, C. S. Leblond, S. Lumbroso, W. Camu, B. Neitzel, O. Onodera, W. van Rheenen, S. Pinto, M. Weber, B. Smith, M. Proven, K. Talbot, P. Keagle, A. Chesi, A. Ratti, J. van der Zee, H. Alstermark, A. Birve, D. Calini, A. Nordin, D. C. Tradowsky, W. Just, H. Daoud, S. Angerbauer, M. DeJesus-Hernandez, T. Konno, A. Lloyd-Jani, M. de Carvalho,
Published in: Journal of Medical Genetics, Issue 51/6, 2014, Page(s) 419-424, ISSN 0022-2593
DOI: 10.1136/jmedgenet-2014-102360

Genetic and biochemical markers in patients with Alzheimer's disease support a concerted systemic iron homeostasis dysregulation

Author(s): Ângela C. Crespo, Bruno Silva, Liliana Marques, Erica Marcelino, Carolina Maruta, Sónia Costa, Ângela Timóteo, Arminda Vilares, Frederico Simões Couto, Paula Faustino, Ana Paula Correia, Ana Verdelho, Graça Porto, Manuela Guerreiro, Ana Herrero, Cristina Costa, Alexandre de Mendonça, Luciana Costa, Madalena Martins
Published in: Neurobiology of Aging, Issue 35/4, 2014, Page(s) 777-785, ISSN 0197-4580
DOI: 10.1016/j.neurobiolaging.2013.10.078

Adenosine A2A Receptors as novel upstream regulators of BDNF-mediated attenuation of hippocampal Long-Term Depression (LTD)

Author(s): Tiago M. Rodrigues, André Jerónimo-Santos, Ana M. Sebastião, Maria José Diógenes
Published in: Neuropharmacology, Issue 79, 2014, Page(s) 389-398, ISSN 0028-3908
DOI: 10.1016/j.neuropharm.2013.12.010

Vascular endothelial growth factor and amyotrophic lateral sclerosis: The interplay with exercise and noninvasive ventilation

Published in: ISSN 0148-639X
DOI: 10.1002/mus.23955

GlyT1 and GlyT2 in brain astrocytes: expression, distribution and function

Author(s): Rita I. Aroeira, Ana M. Sebastião, Cláudia A. Valente
Published in: Brain Structure and Function, Issue 219/3, 2014, Page(s) 817-830, ISSN 1863-2653
DOI: 10.1007/s00429-013-0537-3

Nerve excitabitability and fasciculations

Author(s): Mamede de Carvalho
Published in: Clinical Neurophysiology, Issue 124/10, 2013, Page(s) 1925, ISSN 1388-2457
DOI: 10.1016/j.clinph.2013.03.022

Quality of life in patients with cognitive impairment: validation of the Quality of Life–Alzheimer's Disease scale in Portugal

Author(s): Helena Bárrios, Ana Verdelho, Sofia Narciso, Manuel Gonçalves-Pereira, Rebecca Logsdon, Alexandre de Mendonça
Published in: International Psychogeriatrics, Issue 25/07, 2013, Page(s) 1085-1096, ISSN 1041-6102
DOI: 10.1017/S1041610213000379

A1R–A2AR heteromers coupled to Gs and Gi/0 proteins modulate GABA transport into astrocytes

Author(s): Sofia Cristóvão-Ferreira, Gemma Navarro, Marc Brugarolas, Kamil Pérez-Capote, Sandra H. Vaz, Giorgia Fattorini, Fiorenzo Conti, Carmen Lluis, Joaquim A. Ribeiro, Peter J. McCormick, Vicent Casadó, Rafael Franco, Ana M. Sebastião
Published in: Purinergic Signalling, Issue 9/3, 2013, Page(s) 433-449, ISSN 1573-9538
DOI: 10.1007/s11302-013-9364-5

Origin of Fasciculations in Amyotrophic Lateral Sclerosis and Benign Fasciculation Syndrome

Author(s): Mamede de Carvalho, Michael Swash
Published in: JAMA Neurology, 2013, ISSN 2168-6149
DOI: 10.1001/jamaneurol.2013.4437

Do MCI patients with vitamin B12 deficiency have distinctive cognitive deficits?

Author(s): Dina Silva, Ulrike Albers, Isabel Santana, Margarida Vicente, Isabel Martins, Ana Verdelho, Manuela Guerreiro, Alexandre de-Mendonça
Published in: BMC Research Notes, Issue 6/1, 2013, Page(s) 357, ISSN 1756-0500
DOI: 10.1186/1756-0500-6-357

Reduced Myocardial 123-Iodine Metaiodobenzylguanidine Uptake: A Prognostic Marker in Familial Amyloid Polyneuropathy

Published in: ISSN 1941-9651
DOI: 10.1161/CIRCIMAGING.112.000367

Activation of Type 1 Cannabinoid Receptor (CB1R) Promotes Neurogenesis in Murine Subventricular Zone Cell Cultures

Author(s): Sara Xapelli, Fabienne Agasse, Laura Sardà-Arroyo, Liliana Bernardino, Tiago Santos, Filipa F. Ribeiro, Jorge Valero, José Bragança, Clarissa Schitine, Ricardo A. de Melo Reis, Ana M. Sebastião, João O. Malva
Published in: PLoS ONE, Issue 8/5, 2013, Page(s) e63529, ISSN 1932-6203
DOI: 10.1371/journal.pone.0063529

Hypoxia–Ischemia Alters Nucleotide and Nucleoside Catabolism and Na+,K+-ATPase Activity in the Cerebral Cortex of Newborn Rats

Author(s): Victor Camera Pimentel, Daniela Zanini, Andréia Machado Cardoso, Roberta Schmatz, Margarete Dulce Bagatini, Jessié Martins Gutierres, Fabiano Carvalho, Jéssica Lopes Gomes, Maribel Rubin, Vera Maria Morsch, Maria Beatriz Moretto, Mariana Colino-Oliveira, Ana Maria Sebastião, Maria Rosa Chitolina Schetinger
Published in: Neurochemical Research, Issue 38/4, 2013, Page(s) 886-894, ISSN 0364-3190
DOI: 10.1007/s11064-013-0994-3

No association between VAPB mutations and familial or sporadic ALS in Sweden, Portugal and Iceland

Author(s): Caroline Ingre, Susana Pinto, Anna Birve, Rayomand Press, Olof Danielsson, Mamede de Carvalho, Grétar Guđmundsson, Peter M. Andersen
Published in: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Issue 14/7-8, 2013, Page(s) 620-627, ISSN 2167-8421
DOI: 10.3109/21678421.2013.822515

Adenosine: setting the stage for plasticity

Author(s): Raquel B. Dias, Diogo M. Rombo, Joaquim A. Ribeiro, Jeremy M. Henley, Ana M. Sebastião
Published in: Trends in Neurosciences, Issue 36/4, 2013, Page(s) 248-257, ISSN 0166-2236
DOI: 10.1016/j.tins.2012.12.003

Early Changes of Neuromuscular Transmission in the SOD1(G93A) Mice Model of ALS Start Long before Motor Symptoms Onset

Author(s): Mariana C. Rocha, Paula A. Pousinha, Alexandra M. Correia, Ana M. Sebastião, Joaquim A. Ribeiro
Published in: PLoS ONE, Issue 8/9, 2013, Page(s) e73846, ISSN 1932-6203
DOI: 10.1371/journal.pone.0073846

Controversies and priorities in amyotrophic lateral sclerosis

Author(s): Martin R Turner, Orla Hardiman, Michael Benatar, Benjamin R Brooks, Adriano Chio, Mamede de Carvalho, Paul G Ince, Cindy Lin, Robert G Miller, Hiroshi Mitsumoto, Garth Nicholson, John Ravits, Pamela J Shaw, Michael Swash, Kevin Talbot, Bryan J Traynor, Leonard H Van den Berg, Jan H Veldink, Steve Vucic, Matthew C Kiernan
Published in: The Lancet Neurology, Issue 12/3, 2013, Page(s) 310-322, ISSN 1474-4422
DOI: 10.1016/S1474-4422(13)70036-X

Evidence that conditioned avoidance responses are reinforced by positive prediction errors signaled by tonic striatal dopamine

Author(s): Patricia A. Dombrowski, Tiago V. Maia, Suelen L. Boschen, Mariza Bortolanza, Etieli Wendler, Rainer K.W. Schwarting, Marcus Lira Brandão, Philip Winn, Charles D. Blaha, Claudio Da Cunha
Published in: Behavioural Brain Research, Issue 241, 2013, Page(s) 112-119, ISSN 0166-4328
DOI: 10.1016/j.bbr.2012.06.031

Tauroursodeoxycholic acid suppresses amyloid β-induced synaptic toxicity in vitro and in APP/PS1 mice

Author(s): Rita M. Ramalho, Ana F. Nunes, Raquel B. Dias, Joana D. Amaral, Adrian C. Lo, Rudi D'Hooge, Ana M. Sebastião, Cecilia M.P. Rodrigues
Published in: Neurobiology of Aging, Issue 34/2, 2013, Page(s) 551-561, ISSN 0197-4580
DOI: 10.1016/j.neurobiolaging.2012.04.018

Split-hand to diagnosis shot

Author(s): Mamede de Carvalho
Published in: Clinical Neurophysiology, Issue 124/2, 2013, Page(s) 219-220, ISSN 1388-2457
DOI: 10.1016/j.clinph.2012.08.015

A Pan-European Study of the C9orf72 Repeat Associated with FTLD: Geographic Prevalence, Genomic Instability, and Intermediate Repeats

Published in: ISSN 1059-7794
DOI: 10.1002/humu.22244

Ischemia-induced synaptic plasticity drives sustained expression of calcium-permeable AMPA receptors in the hippocampus

Author(s): Raquel B. Dias, Diogo M. Rombo, Joaquim A. Ribeiro, Ana M. Sebastião
Published in: Neuropharmacology, Issue 65, 2013, Page(s) 114-122, ISSN 0028-3908
DOI: 10.1016/j.neuropharm.2012.09.016

Lipid rafts, synaptic transmission and plasticity: Impact in age-related neurodegenerative diseases

Author(s): Ana M. Sebastião, Mariana Colino-Oliveira, Natália Assaife-Lopes, Raquel B. Dias, Joaquim A. Ribeiro
Published in: Neuropharmacology, Issue 64, 2013, Page(s) 97-107, ISSN 0028-3908
DOI: 10.1016/j.neuropharm.2012.06.053

Rapidly progressive frontotemporal dementia and bulbar amyotrophic lateral sclerosis in Portuguese patients with C9orf72 mutation

Author(s): Catarina Chester, Mamede de Carvalho, Gabriel Miltenberger, Sónia Pereira, Lubina Dillen, Julie van der Zee, Christine van Broeckhoven, Alexandre de Mendonça
Published in: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Issue 14/1, 2013, Page(s) 70-72, ISSN 2167-8421
DOI: 10.3109/17482968.2012.690418

Orofacial Apraxia in Motor Neuron Disease

Author(s): Patrícia Pita Lobo, Susana Pinto, Luz Rocha, Sofia Reimão, Mamede de Carvalho
Published in: Case Reports in Neurology, Issue 5/1, 2013, Page(s) 47-51, ISSN 1662-680X
DOI: 10.1159/000349895

Phenotypic variability of familial and sporadic Progranulin p.Gln257Profs*27 mutation

Author(s): Pires C, Coelho M, Valadas A, Barroso C, Pimentel J, Martins M, Duyckaerts C, de Mendonça A, Verdelho A, Miltenberger-Miltenyi G
Published in: J Alzheimers Dis. 2013;37(2):335-42, 2013, ISSN 1875-8908
DOI: 10.3233/JAD-130146

Quality of life in patients with mild cognitive impairment

Published in: ISSN 1360-7863
DOI: 10.1080/13607863.2012.747083

Prediction of long-term (5 years) conversion to dementia using neuropsychological tests in a memory clinic setting

Author(s): Silva D, Guerreiro M, Santana I, Rodrigues A, Cardoso S, Maroco J, de Mendonça A.
Published in: J Alzheimers Dis. 2013;34(3):681-9, 2013, ISSN 1875-8908
DOI: 10.3233/JAD-122098

Regulation of TrkB receptor translocation to lipid rafts by adenosine A2A receptors and its functional implications for BDNF-induced regulation of synaptic plasticity

Author(s): Natália Assaife-Lopes, Vasco C. Sousa, Daniela B. Pereira, Joaquim A. Ribeiro, Ana M. Sebastião
Published in: Purinergic Signalling, Issue 10/2, 2014, Page(s) 251-267, ISSN 1573-9538
DOI: 10.1007/s11302-013-9383-2

Role of Adenosine Receptors in Epileptic Seizures

Author(s): Diogo Miguel Rombo, Joaquim Alexandre Ribeiro, Ana Maria Sebastião
Published in: The Adenosine Receptors, 2018, Page(s) 309-350
DOI: 10.1007/978-3-319-90808-3_13

Neurologic complications of craniovertebral dislocation

Author(s): Mamede de Carvalho, Michael Swash
Published in: Neurologic Aspects of Systemic Disease Part I, 2014, Page(s) 435-448
DOI: 10.1016/B978-0-7020-4086-3.00028-X

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