The inflammatory gene expression program in macrophages: An integrative approach for the systematic characterization of transcriptional co-regulators

Project Information

MEDICI

Grant agreement ID: 692789

DOI 10.3030/692789

Project closed

EC signature date 27 July 2016

Start date 1 November 2016

End date 31 October 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 500 000,00

EU contribution € 2 500 000,00

Coordinated by

ISTITUTO EUROPEO DI ONCOLOGIA SRL
Italy

Publications

Peer reviewed articles (8)

H3K9 trimethylation in active chromatin restricts the usage of functional CTCF sites in SINE B2 repeats

Author(s): Francesco Gualdrini; Sara Polletti; Marta Simonatto; Elena Prosperini; Francesco Pileri; Gioacchino Natoli
Published in: Genes & Development, Issue 1, 2022, ISSN 0890-9369
Publisher: Cold Spring Harbor Laboratory Press
DOI: 10.1101/gad.349282.121

Integration of transcriptional and metabolic control in macrophage activation

Author(s): Gioacchino Natoli; Gioacchino Natoli; Francesco Pileri; Francesco Gualdrini; Serena Ghisletti
Published in: EMBO reports, Issue 3, 2021, ISSN 1469-221X
Publisher: Nature Publishing Group
DOI: 10.15252/embr.202153251

Dissection of acute stimulus-inducible nucleosome remodeling in mammalian cells

Author(s): Federico Comoglio, Marta Simonatto, Sara Polletti, Xin Liu, Stephen T. Smale, Iros Barozzi, Gioacchino Natoli
Published in: Genes & Development, Issue 33/17-18, 2019, Page(s) 1159-1174, ISSN 0890-9369
Publisher: Cold Spring Harbor Laboratory Press
DOI: 10.1101/gad.326348.119

Housekeeping and tissue-specific cis-regulatory elements: Recipes for specificity and recipes for activity

Author(s): Marta Russo, Gioacchino Natoli, Serena Ghisletti
Published in: Transcription, Issue 9/3, 2017, Page(s) 177-181, ISSN 2154-1264
Publisher: Friedrich-Berlin-Verlag
DOI: 10.1080/21541264.2017.1378158

Transcriptional determination and functional specificity of myeloid cells: making sense of diversity

Author(s): Silvia Monticelli, Gioacchino Natoli
Published in: Nature Reviews Immunology, Issue 17/10, 2017, Page(s) 595-607, ISSN 1474-1733
Publisher: Nature Publishing Group
DOI: 10.1038/nri.2017.51

Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation

Author(s): Sergi Cuartero, Felix D. Weiss, Gopuraja Dharmalingam, Ya Guo, Elizabeth Ing-Simmons, Silvia Masella, Irene Robles-Rebollo, Xiaolin Xiao, Yi-Fang Wang, Iros Barozzi, Dounia Djeghloul, Mariane T. Amano, Henri Niskanen, Enrico Petretto, Robin D. Dowell, Kikuë Tachibana, Minna U. Kaikkonen, Kim A. Nasmyth, Boris Lenhard, Gioacchino Natoli, Amanda G. Fisher, Matthias Merkenschlager
Published in: Nature Immunology, Issue 19/9, 2018, Page(s) 932-941, ISSN 1529-2908
Publisher: Nature Publishing Group
DOI: 10.1038/s41590-018-0184-1

Adaptation and memory in immune responses

Author(s): Gioacchino Natoli, Renato Ostuni
Published in: Nature Immunology, Issue 20/7, 2019, Page(s) 783-792, ISSN 1529-2908
Publisher: Nature Publishing Group
DOI: 10.1038/s41590-019-0399-9

A first exon termination checkpoint preferentially suppresses extragenic transcription

Author(s): Liv M. I. Austenaa, Viviana Piccolo, Marta Russo, Elena Prosperini, Sara Polletti, Danilo Polizzese, Serena Ghisletti, Iros Barozzi, Giuseppe R. Diaferia, Gioacchino Natoli
Published in: Nature Structural and Molecular Biology, 2021, ISSN 1545-9993
Publisher: Nature Publishing Group
DOI: 10.1038/s41594-021-00572-y