Publications Peer reviewed articles (38) CTCF is dispensable for immune cell transdifferentiation but facilitates an acute inflammatory response Author(s): Grégoire Stik, Enrique Vidal, Mercedes Barrero, Sergi Cuartero, Maria Vila-Casadesús, Julen Mendieta-Esteban, Tian V. Tian, Jinmi Choi, Clara Berenguer, Amaya Abad, Beatrice Borsari, François le Dily, Patrick Cramer, Marc A. Marti-Renom, Ralph Stadhouders, Thomas Graf Published in: Nature Genetics, Issue 52/7, 2020, Page(s) 655-661, ISSN 1061-4036 Publisher: Nature Publishing Group DOI: 10.1038/s41588-020-0643-0 TT‐seq captures enhancer landscapes immediately after T‐cell stimulation Author(s): Margaux Michel, Carina Demel, Benedikt Zacher, Björn Schwalb, Stefan Krebs, Helmut Blum, Julien Gagneur, Patrick Cramer Published in: Molecular Systems Biology, Issue 13/3, 2017, Page(s) 920, ISSN 1744-4292 Publisher: Nature Publishing Group DOI: 10.15252/msb.20167507 Accurate Promoter and Enhancer Identification in 127 ENCODE and Roadmap Epigenomics Cell Types and Tissues by GenoSTAN Author(s): Benedikt Zacher, Margaux Michel, Björn Schwalb, Patrick Cramer, Achim Tresch, Julien Gagneur Published in: PLOS ONE, Issue 12/1, 2017, Page(s) e0169249, ISSN 1932-6203 Publisher: Public Library of Science DOI: 10.1371/journal.pone.0169249 CDK9-dependent RNA polymerase II pausing controls transcription initiation Author(s): Saskia Gressel, Björn Schwalb, Tim Michael Decker, Weihua Qin, Heinrich Leonhardt, Dirk Eick, Patrick Cramer Published in: eLife, Issue 6, 2017, ISSN 2050-084X Publisher: eLife Sciences Publications DOI: 10.7554/eLife.29736 Mechanism of RNA polymerase II stalling by DNA alkylation Author(s): Stefano Malvezzi, Lucas Farnung, Claudia M. N. Aloisi, Todor Angelov, Patrick Cramer, Shana J. Sturla Published in: Proceedings of the National Academy of Sciences, Issue 114/46, 2017, Page(s) 12172-12177, ISSN 0027-8424 Publisher: National Academy of Sciences DOI: 10.1073/pnas.1706592114 RNA-dependent chromatin association of transcription elongation factors and Pol II CTD kinases Author(s): Sofia Battaglia, Michael Lidschreiber, Carlo Baejen, Phillipp Torkler, Seychelle M Vos, Patrick Cramer Published in: eLife, Issue 6, 2017, ISSN 2050-084X Publisher: eLife Sciences Publications DOI: 10.7554/eLife.25637 Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex Author(s): Youwei Xu, Carrie Bernecky, Chung-Tien Lee, Kerstin C. Maier, Björn Schwalb, Dimitry Tegunov, Jürgen M. Plitzko, Henning Urlaub, Patrick Cramer Published in: Nature Communications, Issue 8, 2017, Page(s) 15741, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/ncomms15741 Structure of transcribing RNA polymerase II-nucleosome complex Author(s): Lucas Farnung, Seychelle M. Vos, Patrick Cramer Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-018-07870-y Structures of transcription pre-initiation complex with TFIIH and Mediator Author(s): S. Schilbach, M. Hantsche, D. Tegunov, C. Dienemann, C. Wigge, H. Urlaub, P. Cramer Published in: Nature, 2017, ISSN 0028-0836 Publisher: Nature Publishing Group DOI: 10.1038/nature24282 Genome-wide Analysis of RNA Polymerase II Termination at Protein-Coding Genes Author(s): Carlo Baejen, Jessica Andreani, Phillipp Torkler, Sofia Battaglia, Bjoern Schwalb, Michael Lidschreiber, Kerstin C. Maier, Andrea Boltendahl, Petra Rus, Stephanie Esslinger, Johannes Söding, Patrick Cramer Published in: Molecular Cell, Issue 66/1, 2017, Page(s) 38-49.e6, ISSN 1097-2765 Publisher: Cell Press DOI: 10.1016/j.molcel.2017.02.009 Structural Basis of Mitochondrial Transcription Initiation Author(s): Hauke S. Hillen, Yaroslav I. Morozov, Azadeh Sarfallah, Dmitry Temiakov, Patrick Cramer Published in: Cell, Issue 171/5, 2017, Page(s) 1072-1081.e10, ISSN 0092-8674 Publisher: Cell Press DOI: 10.1016/j.cell.2017.10.036 Architecture of a transcribing-translating expressome Author(s): R. Kohler, R. A. Mooney, D. J. Mills, R. Landick, P. Cramer Published in: Science, Issue 356/6334, 2017, Page(s) 194-197, ISSN 0036-8075 Publisher: American Association for the Advancement of Science DOI: 10.1126/science.aal3059 The APT complex is involved in non-coding RNA transcription and is distinct from CPF Author(s): Michael Lidschreiber, Ashley D Easter, Sofia Battaglia, Juan B Rodríguez-Molina, Ana Casañal, Manuel Carminati, Carlo Baejen, Pawel Grzechnik, Kerstin C Maier, Patrick Cramer, Lori A Passmore Published in: Nucleic Acids Research, 2018, ISSN 0305-1048 Publisher: Oxford University Press DOI: 10.1093/nar/gky845 Structure of paused transcription complex Pol II–DSIF–NELF Author(s): Seychelle M. Vos, Lucas Farnung, Henning Urlaub, Patrick Cramer Published in: Nature, Issue 560/7720, 2018, Page(s) 601-606, ISSN 0028-0836 Publisher: Nature Publishing Group DOI: 10.1038/s41586-018-0442-2 Structural Molecular Biology—A Personal Reflection on the Occasion of John Kendrew's 100th Birthday Author(s): Patrick Cramer Published in: Journal of Molecular Biology, Issue 429/17, 2017, Page(s) 2603-2610, ISSN 0022-2836 Publisher: Academic Press DOI: 10.1016/j.jmb.2017.05.007 Nucleosome–Chd1 structure and implications for chromatin remodelling Author(s): Lucas Farnung, Seychelle M. Vos, Christoph Wigge, Patrick Cramer Published in: Nature, Issue 550/7677, 2017, Page(s) 539-542, ISSN 0028-0836 Publisher: Nature Publishing Group DOI: 10.1038/nature24046 Structural Basis of RNA Polymerase I Transcription Initiation Author(s): Christoph Engel, Tobias Gubbey, Simon Neyer, Sarah Sainsbury, Christiane Oberthuer, Carlo Baejen, Carrie Bernecky, Patrick Cramer Published in: Cell, Issue 169/1, 2017, Page(s) 120-131.e22, ISSN 0092-8674 Publisher: Cell Press DOI: 10.1016/j.cell.2017.03.003 Spt5 Plays Vital Roles in the Control of Sense and Antisense Transcription Elongation Author(s): Ameet Shetty, Scott P. Kallgren, Carina Demel, Kerstin C. Maier, Dan Spatt, Burak H. Alver, Patrick Cramer, Peter J. Park, Fred Winston Published in: Molecular Cell, Issue 66/1, 2017, Page(s) 77-88.e5, ISSN 1097-2765 Publisher: Cell Press DOI: 10.1016/j.molcel.2017.02.023 Mechanism of Transcription Anti-termination in Human Mitochondria Author(s): Hauke S. Hillen, Andrey V. Parshin, Karen Agaronyan, Yaroslav I. Morozov, James J. Graber, Aleksandar Chernev, Kathrin Schwinghammer, Henning Urlaub, Michael Anikin, Patrick Cramer, Dmitry Temiakov Published in: Cell, Issue 171/5, 2017, Page(s) 1082-1093.e13, ISSN 0092-8674 Publisher: Cell Press DOI: 10.1016/j.cell.2017.09.035 The Implication of Early Chromatin Changes in X Chromosome Inactivation Author(s): Jan Jakub Żylicz, Aurélie Bousard, Kristina Žumer, Francois Dossin, Eusra Mohammad, Simão Teixeira da Rocha, Björn Schwalb, Laurène Syx, Florent Dingli, Damarys Loew, Patrick Cramer, Edith Heard Published in: Cell, Issue 176/1-2, 2019, Page(s) 182-197.e23, ISSN 0092-8674 Publisher: Cell Press DOI: 10.1016/j.cell.2018.11.041 Conserved RNA polymerase II initiation complex structure Author(s): Merle Hantsche, Patrick Cramer Published in: Current Opinion in Structural Biology, Issue 47, 2017, Page(s) 17-22, ISSN 0959-440X Publisher: Elsevier BV DOI: 10.1016/j.sbi.2017.03.013 Structural basis of TFIIH activation for nucleotide excision repair Author(s): Goran Kokic, Aleksandar Chernev, Dimitry Tegunov, Christian Dienemann, Henning Urlaub, Patrick Cramer Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-019-10745-5 Transcriptome maps of general eukaryotic RNA degradation factors Author(s): Salma Sohrabi-Jahromi, Katharina B Hofmann, Andrea Boltendahl, Christian Roth, Saskia Gressel, Carlo Baejen, Johannes Soeding, Patrick Cramer Published in: eLife, Issue 8, 2019, ISSN 2050-084X Publisher: eLife Sciences Publications DOI: 10.7554/elife.47040 Global donor and acceptor splicing site kinetics in human cells Author(s): Leonhard Wachutka, Livia Caizzi, Julien Gagneur, Patrick Cramer Published in: eLife, Issue 8, 2019, ISSN 2050-084X Publisher: eLife Sciences Publications DOI: 10.7554/elife.45056 NASC-seq monitors RNA synthesis in single cells Author(s): Gert-Jan Hendriks, Lisa A. Jung, Anton J. M. Larsson, Michael Lidschreiber, Oscar Andersson Forsman, Katja Lidschreiber, Patrick Cramer, Rickard Sandberg Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-019-11028-9 Structure of activated transcription complex Pol II–DSIF–PAF–SPT6 Author(s): Seychelle M. Vos, Lucas Farnung, Marc Boehning, Christoph Wigge, Andreas Linden, Henning Urlaub, Patrick Cramer Published in: Nature, Issue 560/7720, 2018, Page(s) 607-612, ISSN 0028-0836 Publisher: Nature Publishing Group DOI: 10.1038/s41586-018-0440-4 Structure of a transcribing RNA polymerase II–DSIF complex reveals a multidentate DNA–RNA clamp Author(s): Carrie Bernecky, Jürgen M Plitzko, Patrick Cramer Published in: Nature Structural & Molecular Biology, Issue 24/10, 2017, Page(s) 809-815, ISSN 1545-9993 Publisher: Nature Publishing Group DOI: 10.1038/nsmb.3465 Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome Author(s): Felix R. Wagner, Christian Dienemann, Haibo Wang, Alexandra Stützer, Dimitry Tegunov, Henning Urlaub, Patrick Cramer Published in: Nature, Issue 579/7799, 2020, Page(s) 448-451, ISSN 0028-0836 Publisher: Nature Publishing Group DOI: 10.1038/s41586-020-2088-0 Structure of H3K36-methylated nucleosome–PWWP complex reveals multivalent cross-gyre binding Author(s): Haibo Wang, Lucas Farnung, Christian Dienemann, Patrick Cramer Published in: Nature Structural & Molecular Biology, Issue 27/1, 2020, Page(s) 8-13, ISSN 1545-9993 Publisher: Nature Publishing Group DOI: 10.1038/s41594-019-0345-4 Structure of replicating SARS-CoV-2 polymerase Author(s): Hauke S. Hillen, Goran Kokic, Lucas Farnung, Christian Dienemann, Dimitry Tegunov, Patrick Cramer Published in: Nature, 2020, ISSN 0028-0836 Publisher: Nature Publishing Group DOI: 10.1038/s41586-020-2368-8 The pause-initiation limit restricts transcription activation in human cells Author(s): Saskia Gressel, Björn Schwalb, Patrick Cramer Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-019-11536-8 Real-time cryo-electron microscopy data preprocessing with Warp Author(s): Dimitry Tegunov, Patrick Cramer Published in: Nature Methods, Issue 16/11, 2019, Page(s) 1146-1152, ISSN 1548-7091 Publisher: Nature Publishing Group DOI: 10.1038/s41592-019-0580-y Structure of the super-elongation complex subunit AFF4 C-terminal homology domain reveals requirements for AFF homo- and heterodimerization Author(s): Ying Chen, Patrick Cramer Published in: Journal of Biological Chemistry, Issue 294/27, 2019, Page(s) 10663-10673, ISSN 0021-9258 Publisher: American Society for Biochemistry and Molecular Biology Inc. DOI: 10.1074/jbc.ra119.008577 Nucleosome-CHD4 chromatin remodeler structure maps human disease mutations Author(s): Lucas Farnung, Moritz Ochmann, Patrick Cramer Published in: eLife, Issue 9, 2020, ISSN 2050-084X Publisher: eLife Sciences Publications DOI: 10.7554/elife.56178 Organization and regulation of gene transcription Author(s): Patrick Cramer Published in: Nature, Issue 573/7772, 2019, Page(s) 45-54, ISSN 0028-0836 Publisher: Nature Publishing Group DOI: 10.1038/s41586-019-1517-4 Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function Author(s): Svetlana O. Dodonova, Fangjie Zhu, Christian Dienemann, Jussi Taipale, Patrick Cramer Published in: Nature, Issue 580/7805, 2020, Page(s) 669-672, ISSN 0028-0836 Publisher: Nature Publishing Group DOI: 10.1038/s41586-020-2195-y Structure of complete Pol II–DSIF–PAF–SPT6 transcription complex reveals RTF1 allosteric activation Author(s): Seychelle M. Vos, Lucas Farnung, Andreas Linden, Henning Urlaub, Patrick Cramer Published in: Nature Structural & Molecular Biology, Issue 27/7, 2020, Page(s) 668-677, ISSN 1545-9993 Publisher: Nature Publishing Group DOI: 10.1038/s41594-020-0437-1 Structure of the transcription coactivator SAGA Author(s): Haibo Wang, Christian Dienemann, Alexandra Stützer, Henning Urlaub, Alan C. M. Cheung, Patrick Cramer Published in: Nature, Issue 577/7792, 2020, Page(s) 717-720, ISSN 0028-0836 Publisher: Nature Publishing Group DOI: 10.1038/s41586-020-1933-5 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available