Force nanoscopy of staphylococcal biofilms

Project Information

NanoStaph

Grant agreement ID: 693630

DOI

10.3030/693630

Project closed

EC signature date 12 May 2016

Start date 1 October 2016

End date 30 September 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 481 437,50

EU contribution

€ 2 481 437,50

Coordinated by

UNIVERSITE CATHOLIQUE DE LOUVAIN
Belgium

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (16)

How Microbes Use Force To Control Adhesion

Author(s): Albertus Viljoen, Johann Mignolet, Felipe Viela, Marion Mathelié-Guinlet, Yves F. Dufrêne
Published in: Journal of Bacteriology, Issue 202/12, 2020, ISSN 0021-9193
Publisher: American Society for Microbiology
DOI: 10.1128/jb.00125-20

Staphylococcus aureus binds to the N-terminal region of corneodesmosin to adhere to the stratum corneum in atopic dermatitis

Author(s): Aisling M. Towell, Cécile Feuillie, Pauline Vitry, Thaina M. Da Costa, Marion Mathelié-Guinlet, Sanja Kezic, Orla M. Fleury, Maeve A. McAleer, Yves F. Dufrêne, Alan D. Irvine, Joan A. Geoghegan
Published in: Proceedings of the National Academy of Sciences, Issue 118/1, 2020, Page(s) e2014444118, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2014444118

Mechanomicrobiology: how bacteria sense and respond to forces

Author(s): Yves F. Dufrêne, Alexandre Persat
Published in: Nature Reviews Microbiology, Issue 18/4, 2020, Page(s) 227-240, ISSN 1740-1526
Publisher: Nature Publishing Group
DOI: 10.1038/s41579-019-0314-2

Force-clamp spectroscopy identifies a catch bond mechanism in a Gram-positive pathogen

Author(s): Marion Mathelié-Guinlet, Felipe Viela, Giampiero Pietrocola, Pietro Speziale, David Alsteens, Yves F. Dufrêne
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-19216-8

What makes bacterial pathogens so sticky?

Author(s): Felipe Viela, Marion Mathelié‐Guinlet, Albertus Viljoen, Yves F. Dufrêne
Published in: Molecular Microbiology, Issue 113/4, 2020, Page(s) 683-690, ISSN 0950-382X
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/mmi.14448

Binding Strength of Gram-Positive Bacterial Adhesins

Author(s): Yves F. Dufrêne, Albertus Viljoen
Published in: Frontiers in Microbiology, Issue 11, 2020, ISSN 1664-302X
Publisher: Frontiers Media
DOI: 10.3389/fmicb.2020.01457

Stress-Induced Catch-Bonds to Enhance Bacterial Adhesion

Author(s): Marion Mathelié-Guinlet, Felipe Viela, David Alsteens, Yves F. Dufrêne
Published in: Trends in Microbiology, Issue 29/4, 2021, Page(s) 286-288, ISSN 0966-842X
Publisher: Elsevier BV
DOI: 10.1016/j.tim.2020.11.009

Molecular interactions and inhibition of the staphylococcal biofilm-forming protein SdrC

Author(s): Cécile Feuillie, Cécile Formosa-Dague, Leanne M. C. Hays, Ophélie Vervaeck, Sylvie Derclaye, Marian P. Brennan, Timothy J. Foster, Joan A. Geoghegan, Yves F. Dufrêne
Published in: Proceedings of the National Academy of Sciences, Issue 114/14, 2017, Page(s) 3738-3743, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1616805114

Fibrinogen Activates the Capture of Human Plasminogen by Staphylococcal Fibronectin-Binding Proteins

Author(s): Philippe Herman-Bausier, Giampiero Pietrocola, Timothy J. Foster, Pietro Speziale, Yves F. Dufrêne
Published in: mBio, Issue 8/5, 2017, ISSN 2150-7511
Publisher: -
DOI: 10.1128/mbio.01067-17

Single-Cell and Single-Molecule Analysis Unravels the Multifunctionality of the Staphylococcus aureus Collagen-Binding Protein Cna

Author(s): Claire Valotteau, Valeria Prystopiuk, Giampiero Pietrocola, Simonetta Rindi, Daniele Peterle, Vincenzo De Filippis, Timothy J. Foster, Pietro Speziale, Yves F. Dufrêne
Published in: ACS Nano, Issue 11/2, 2017, Page(s) 2160-2170, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.6b08404

Force-Induced Strengthening of the Interaction between Staphylococcus aureus Clumping Factor B and Loricrin

Author(s): Pauline Vitry, Claire Valotteau, Cécile Feuillie, Simon Bernard, David Alsteens, Joan A. Geoghegan, Yves F. Dufrêne
Published in: mBio, Issue 8/6, 2017, ISSN 2150-7511
Publisher: ASM
DOI: 10.1128/mbio.01748-17

Staphylococcus aureus clumping factor A is a force-sensitive molecular switch that activates bacterial adhesion

Author(s): Philippe Herman-Bausier, Cristina Labate, Aisling M. Towell, Sylvie Derclaye, Joan A. Geoghegan, Yves F. Dufrêne
Published in: Proceedings of the National Academy of Sciences, Issue 115/21, 2018, Page(s) 5564-5569, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1718104115

Live-Cell Nanoscopy in Antiadhesion Therapy

Author(s): Joan A. Geoghegan, Timothy J. Foster, Pietro Speziale, Yves F. Dufrêne
Published in: Trends in Microbiology, Issue 25/7, 2017, Page(s) 512-514, ISSN 0966-842X
Publisher: Elsevier BV
DOI: 10.1016/j.tim.2017.04.002

Mechanical Forces Guiding Staphylococcus aureus Cellular Invasion

Author(s): Valeria Prystopiuk, Cécile Feuillie, Philippe Herman-Bausier, Felipe Viela, David Alsteens, Giampiero Pietrocola, Pietro Speziale, Yves F. Dufrêne
Published in: ACS Nano, Issue 12/4, 2018, Page(s) 3609-3622, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.8b00716

The Molecular Complex between Staphylococcal Adhesin SpsD and Fibronectin Sustains Mechanical Forces in the Nanonewton Range

Author(s): Felipe Viela, Marion Mathelié-Guinlet, Giampiero Pietrocola, Pietro Speziale, Yves F. Dufrêne
Published in: mBio, Issue 11/4, 2020, ISSN 2150-7511
Publisher: ASM
DOI: 10.1128/mbio.00371-20

Nanomechanics of the molecular complex between staphylococcal adhesin SpsD and elastin

Author(s): Marion Mathelié-Guinlet, Constance Chantraine, Felipe Viela, Giampiero Pietrocola, Pietro Speziale, Yves F. Dufrêne
Published in: Nanoscale, Issue 12/26, 2020, Page(s) 13996-14003, ISSN 2040-3364
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0nr02745f

Non-peer reviewed articles (1)

Force matters in hospital-acquired infections

Author(s): Philippe Herman-Bausier, Yves F. Dufrêne
Published in: Science, Issue 359/6383, 2018, Page(s) 1464-1465, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aat3764