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CDK6 in transcription - turning a foe in a friend

Publicaciones

The role of CDK6 in cancer

Autores: Sofie Nebenfuehr, Karoline Kollmann, Veronika Sexl
Publicado en: International Journal of Cancer, Edición 147/11, 2020, Página(s) 2988-2995, ISSN 0020-7136
Editor: John Wiley & Sons Inc.
DOI: 10.1002/ijc.33054

CDK6 Degradation Is Counteracted by p16INK4A and p18INK4C in AML

Autores: Belinda S. Schmalzbauer; Teresemary Thondanpallil; Gerwin Heller; Alessia Schirripa; Clio-Melina Sperl; Isabella M. Mayer; Vanessa M. Knab; Sofie Nebenfuehr; Markus Zojer; André C. Mueller; Frédéric Fontaine; Thorsten Klampfl; Veronika Sexl; Karoline Kollmann
Publicado en: Cancers (Basel), Edición 20726694, 2022, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14061554

Isolation, Maintenance and Expansion of Adult Hematopoietic Stem/Progenitor Cells and Leukemic Stem Cells

Autores: Isabella Maria Mayer; Andrea Hoelbl-Kovacic; Veronika Sexl; Eszter Doma
Publicado en: Cancers (Basel), Edición 20726694, 2022, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14071723

A robust approach for the generation of functional hematopoietic progenitor cell lines to model leukemic transformation

Autores: Eszter Doma, Isabella Maria Mayer, Tania Brandstoetter, Barbara Maurer, Reinhard Grausenburger, Ingeborg Menzl, Markus Zojer, Andrea Hoelbl-Kovacic, Leif Carlsson, Gerwin Heller, Karoline Kollmann, Veronika Sexl
Publicado en: Blood Advances, Edición 5/1, 2021, Página(s) 39-53, ISSN 2473-9529
Editor: American Society of Hematology
DOI: 10.1182/bloodadvances.2020003022

The interplay of CDK4 and CDK6 in melanoma

Autores: Karoline Kollmann, Coralie Briand, Florian Bellutti, Nikolaus Schicher, Stefan Blunder, Markus Zojer, Christoph Hoeller
Publicado en: Oncotarget, Edición 10/14, 2019, Página(s) 1346-1359, ISSN 1949-2553
Editor: Impact Journals
DOI: 10.18632/oncotarget.26515

Inducible deletion of CDK4 and CDK6 - deciphering CDK4/6 inhibitor effects in the hematopoietic system

Autores: Barbara Maurer, Tania Brandstoetter, Sebastian Kollmann, Veronika Sexl, Michaela Prchal-Murphy
Publicado en: Haematologica, 2020, Página(s) haematol.2020.256313, ISSN 0390-6078
Editor: Ferrata Storti Foundation
DOI: 10.3324/haematol.2020.256313

CDK4/6 and MAPK—Crosstalk as Opportunity for Cancer Treatment

Autores: Lisa Scheiblecker, Karoline Kollmann, Veronika Sexl
Publicado en: Pharmaceuticals, Edición 13/12, 2020, Página(s) 418, ISSN 1424-8247
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ph13120418

CDK6 Inhibition: A Novel Approach in AML Management

Autores: Iris Z. Uras, Veronika Sexl, Karoline Kollmann
Publicado en: International Journal of Molecular Sciences, Edición 21/7, 2020, Página(s) 2528, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21072528

Cdk6 contributes to cytoskeletal stability in erythroid cells

Autores: Iris Z. Uras, Ruth M. Scheicher, Karoline Kollmann, Martin Glösmann, Michaela Prchal-Murphy, Anca S. Tigan, Daniela A. Fux, Sandro Altamura, Joana Neves, Martina U. Muckenthaler, Keiryn L. Bennett, Stefan Kubicek, Philip W. Hinds, Marieke von Lindern, Veronika Sexl
Publicado en: Haematologica, Edición 102/6, 2017, Página(s) 995-1005, ISSN 0390-6078
Editor: Ferrata Storti Foundation
DOI: 10.3324/haematol.2016.159947

p27 in FLT3-driven acute myeloid leukemia: many roads lead to ruin

Autores: Iris Z Uras, Florian Bellutti, Veronika Sexl
Publicado en: Haematologica, Edición 102/8, 2017, Página(s) 1299-1301, ISSN 0390-6078
Editor: Ferrata Storti Foundation
DOI: 10.3324/haematol.2017.171819

Cdk6: At the interface of Rb and p53

Autores: Sofie Nebenfuehr, Florian Bellutti, Veronika Sexl
Publicado en: Molecular & Cellular Oncology, Edición 5/5, 2018, Página(s) e1511206, ISSN 2372-3556
Editor: Taylor & Francis
DOI: 10.1080/23723556.2018.1511206

CDK6 Antagonizes p53-Induced Responses during Tumorigenesis

Autores: Florian Bellutti, Anca-Sarmiza Tigan, Sofie Nebenfuehr, Marlies Dolezal, Markus Zojer, Reinhard Grausenburger, Svenja Hartenberger, Sebastian Kollmann, Eszter Doma, Michaela Prchal-Murphy, Iris Z. Uras, Alexander Höllein, Donna S. Neuberg, Benjamin L. Ebert, Anna Ringler, Andre C. Mueller, Joanna I. Loizou, Philip W. Hinds, Claus Vogl, Gerwin Heller, Stefan Kubicek, Johannes Zuber, Marcos Malumbr
Publicado en: Cancer Discovery, Edición 8/7, 2018, Página(s) 884-897, ISSN 2159-8274
Editor: American Association for Cancer Research Inc.
DOI: 10.1158/2159-8290.CD-17-0912

CDK6 coordinates JAK2 V617F mutant MPN via NF-κB and apoptotic networks

Autores: Iris Z. Uras, Barbara Maurer, Harini Nivarthi, Philipp Jodl, Karoline Kollmann, Michaela Prchal-Murphy, Jelena D. Milosevic Feenstra, Markus Zojer, Sabine Lagger, Reinhard Grausenburger, Beatrice Grabner, Raimund Holly, Anoop Kavirayani, Christoph Bock, Heinz Gisslinger, Peter Valent, Robert Kralovics, Veronika Sexl
Publicado en: Blood, Edición 133/15, 2019, Página(s) 1677-1690, ISSN 0006-4971
Editor: American Society of Hematology
DOI: 10.1182/blood-2018-08-872648

Therapeutic Vulnerabilities in FLT3-Mutant AML Unmasked by Palbociclib

Autores: Iris Uras, Barbara Maurer, Sofie Nebenfuehr, Markus Zojer, Peter Valent, Veronika Sexl
Publicado en: International Journal of Molecular Sciences, Edición 19/12, 2018, Página(s) 3987, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms19123987

The Effect of CDK6 Expression on DNA Methylation and DNMT3B Regulation

Autores: Gerwin Heller, Sofie Nebenfuehr, Florian Bellutti, Huriye Ünal, Markus Zojer, Lisa Scheiblecker, Veronika Sexl, Karoline Kollmann
Publicado en: iScience, Edición 23/10, 2020, Página(s) 101602, ISSN 2589-0042
Editor: Cell Press
DOI: 10.1016/j.isci.2020.101602

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