Central integration of metabolic and hedonic cues in metabolic health

Project Information

INTEGRATE

Grant agreement ID: 694798

DOI 10.3030/694798

Project closed

EC signature date 28 June 2016

Start date 1 October 2016

End date 30 September 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 499 714,00

EU contribution € 2 499 714,00

Coordinated by

UNIVERSITE DE LAUSANNE
Switzerland

Publications

Peer reviewed articles (7)

Ablation of glucokinase-expressing tanycytes impacts energy balance and increases adiposity in mice

Author(s): Antoine Rohrbach, Emilie Caron, Rafik Dali, Maxime Brunner, Roxane Pasquettaz, Irina Kolotuev, Federico Santoni, Bernard Thorens, Fanny Langlet
Published in: Molecular Metabolism, Issue 53, 2021, Page(s) 101311, ISSN 2212-8778
Publisher: Elsevier GmbH
DOI: 10.1016/j.molmet.2021.101311

EphrinB1 modulates glutamatergic inputs into POMC-expressing progenitors and controls glucose homeostasis

Author(s): Manon Gervais, Gwenaël Labouèbe, Alexandre Picard, Bernard Thorens, Sophie Croizier
Published in: PLOS Biology, Issue 18/11, 2020, Page(s) e3000680, ISSN 1545-7885
Publisher: Public Library of Science PLOS
DOI: 10.1371/journal.pbio.3000680

Hypoglycemia-Sensing Neurons of the Ventromedial Hypothalamus Require AMPK-Induced Txn2 Expression but Are Dispensable for Physiological Counterregulation

Author(s): Simon Quenneville, Gwenaël Labouèbe, Davide Basco, Salima Metref, Benoit Viollet, Marc Foretz, Bernard Thorens
Published in: Diabetes, Issue 69/11, 2020, Page(s) 2253-2266, ISSN 0012-1797
Publisher: American Diabetes Association
DOI: 10.2337/db20-0577

Glucose transporter 2 mediates the hypoglycemia-induced increase in cerebral blood flow

Author(s): Hongxia Lei, Frédéric Preitner, Gwenaël Labouèbe, Rolf Gruetter, Bernard Thorens
Published in: Journal of Cerebral Blood Flow & Metabolism, 2018, Page(s) 0271678X1876674, ISSN 0271-678X
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1177/0271678x18766743

α-cell glucokinase suppresses glucose-regulated glucagon secretion

Author(s): Davide Basco, Quan Zhang, Albert Salehi, Andrei Tarasov, Wanda Dolci, Pedro Herrera, Ioannis Spiliotis, Xavier Berney, David Tarussio, Patrik Rorsman, Bernard Thorens
Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-018-03034-0

Glucokinase neurons of the paraventricular nucleus of the thalamus sense glucose and decrease food consumption

Author(s): Sébastien Kessler, Gwenaël Labouèbe, Sophie Croizier, Sevasti Gaspari, David Tarussio, Bernard Thorens
Published in: iScience, Issue 24/10, 2021, Page(s) 103122, ISSN 2589-0042
Publisher: Elsevier
DOI: 10.1016/j.isci.2021.103122

Fgf15 neurons of the dorsomedial hypothalamus control glucagon secretion and hepatic gluconeogenesis

Author(s): Alexandre Picard, Salima Metref, David Tarussio, Wanda Dolci, Xavier Berney, Sophie Croizier, Gwenaël Labouebe, Bernard Thorens
Published in: Diabetes, 2021, Page(s) db201121, ISSN 0012-1797
Publisher: American Diabetes Association
DOI: 10.2337/db20-1121