Building complex life through self-organization: from organ to organism

Project Information

ORCHESTRATE

Grant agreement ID: 694801

DOI 10.3030/694801

Project closed

EC signature date 23 September 2016

Start date 1 October 2016

End date 30 September 2020

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 655 000,00

EU contribution € 2 655 000,00

Coordinated by

UNIVERSITEIT MAASTRICHT
Netherlands

Publications

Peer reviewed articles (11)

Overlooked? Underestimated? Effects of Substrate Curvature on Cell Behavior

Author(s): Danielle Baptista, Liliana Teixeira, Clemens van Blitterswijk, Stefan Giselbrecht, Roman Truckenmüller
Published in: Trends in Biotechnology, Issue 37/8, 2019, Page(s) 838-854, ISSN 0167-7799
Publisher: Elsevier BV
DOI: 10.1016/j.tibtech.2019.01.006

3D alveolar in vitro model based on epithelialized biomimetically curved culture membranes

Author(s): D. Baptista, L. Moreira Teixeira, Z. Tahmasebi Birgani, S. van Riet, T. Pasman, A. Poot, D. Stamatialis, R.J. Rottier, P.S. Hiemstra, P. Habibović, C. van Blitterswijk, S. Giselbrecht, R. Truckenmüller
Published in: Biomaterials, 2020, Page(s) 120436, ISSN 0142-9612
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2020.120436

Building Complex Life Through Self-Organization

Author(s): Mireille M.J.P.E. Sthijns, Vanessa L.S. LaPointe, Clemens A. van Blitterswijk
Published in: Tissue Engineering Part A, Issue 25/19-20, 2019, Page(s) 1341-1346, ISSN 1937-3341
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/ten.tea.2019.0208

The Role of Alpha Cells in the Self-Assembly of Bioengineered Islets

Author(s): Fredrik C. Wieland, Mireille M.J.P.E. Sthijns, Thomas Geuens, Clemens A. van Blitterswijk, Vanessa L.S. LaPointe
Published in: Tissue Engineering Part A, 2020, ISSN 1937-3341
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/ten.tea.2020.0080

Hydrogels that listen to cells: a review of cell-responsive strategies in biomaterial design for tissue regeneration

Author(s): H. W. Ooi, S. Hafeez, C. A. van Blitterswijk, L. Moroni, M. B. Baker
Published in: Mater. Horiz., Issue 4/6, 2017, Page(s) 1020-1040, ISSN 2051-6347
Publisher: Royal Society of Chemistry
DOI: 10.1039/c7mh00373k

Redox regulation in regenerative medicine and tissue engineering: The paradox of oxygen

Author(s): Mireille M.J.P.E. Sthijns, Clemens A. van Blitterswijk, Vanessa L.S. LaPointe
Published in: Journal of Tissue Engineering and Regenerative Medicine, 2018, ISSN 1932-6254
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/term.2730

A New Microengineered Platform for 4D Tracking of Single Cells in a Stem‐Cell‐Based In Vitro Morphogenesis Model

Author(s): Pinak Samal, Philipp Maurer, Clemens Blitterswijk, Roman Truckenmüller, Stefan Giselbrecht
Published in: Advanced Materials, Issue 32/24, 2020, Page(s) 1907966, ISSN 0935-9648
Publisher: United Nations Industrial Developement Organization
DOI: 10.1002/adma.201907966

Oxygen and nutrient delivery in tissue engineering: Approaches to graft vascularization

Author(s): Timo Rademakers, Judith M. Horvath, Clemens A. Blitterswijk, Vanessa L.S. LaPointe
Published in: Journal of Tissue Engineering and Regenerative Medicine, Issue 13/10, 2019, Page(s) 1815-1829, ISSN 1932-6254
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/term.2932

Oxidative stress in pancreatic alpha and beta cells as a selection criterion for biocompatible biomaterials

Author(s): Mireille M.J.P.E. Sthijns, Marlon J. Jetten, Sami G. Mohammed, Sandra M.H. Claessen, Rick H.W. de Vries, Adam Stell, Denise F.A. de Bont, Marten A. Engelse, Didem Mumcuoglu, Clemens A. van Blitterswijk, Patricia Y.W. Dankers, Eelco J.P. de Koning, Aart A. van Apeldoorn, Vanessa L.S. LaPointe
Published in: Biomaterials, Issue 267, 2021, Page(s) 120449, ISSN 0142-9612
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2020.120449

Blastocyst-like structures generated solely from stem cells

Author(s): Nicolas C. Rivron, Javier Frias-Aldeguer, Erik J. Vrij, Jean-Charles Boisset, Jeroen Korving, Judith Vivié, Roman K. Truckenmüller, Alexander van Oudenaarden, Clemens A. van Blitterswijk, Niels Geijsen
Published in: Nature, Issue 557/7703, 2018, Page(s) 106-111, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-018-0051-0

Viscoelastic Oxidized Alginates with Reversible Imine Type Crosslinks: Self-Healing, Injectable, and Bioprintable Hydrogels

Author(s): Shahzad Hafeez, Huey Ooi, Francis Morgan, Carlos Mota, Monica Dettin, Clemens van Blitterswijk, Lorenzo Moroni, Matthew Baker
Published in: Gels, Issue 4/4, 2018, Page(s) 85, ISSN 2310-2861
Publisher: MDPI
DOI: 10.3390/gels4040085

Other (1)

Chemically-defined induction of a primitive endoderm and epiblast-like niche supports post-implantation progression from blastoids

Author(s): Erik J. Vrij, Yvonne S. Scholte op Reimer, Javier Frias Aldeguer, Isabel Misteli Guerreiro, Jop Kind, Bon-Kyoung Koo, Clemens A. van Blitterswijk, Nicolas C. Rivron
Published in: 2019
Publisher: BioRxiv
DOI: 10.1101/510396