Building complex life through self-organization: from organ to organism

Informazioni relative al progetto

ORCHESTRATE

ID dell’accordo di sovvenzione: 694801

DOI 10.3030/694801

Progetto chiuso

Data della firma CE 23 Settembre 2016

Data di avvio 1 Ottobre 2016

Data di completamento 30 Settembre 2020

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 2 655 000,00

Contributo UE € 2 655 000,00

Coordinato da

UNIVERSITEIT MAASTRICHT
Netherlands

Pubblicazioni

Peer reviewed articles (11)

Overlooked? Underestimated? Effects of Substrate Curvature on Cell Behavior

Autori: Danielle Baptista, Liliana Teixeira, Clemens van Blitterswijk, Stefan Giselbrecht, Roman Truckenmüller
Pubblicato in: Trends in Biotechnology, Numero 37/8, 2019, Pagina/e 838-854, ISSN 0167-7799
Editore: Elsevier BV
DOI: 10.1016/j.tibtech.2019.01.006

3D alveolar in vitro model based on epithelialized biomimetically curved culture membranes

Autori: D. Baptista, L. Moreira Teixeira, Z. Tahmasebi Birgani, S. van Riet, T. Pasman, A. Poot, D. Stamatialis, R.J. Rottier, P.S. Hiemstra, P. Habibović, C. van Blitterswijk, S. Giselbrecht, R. Truckenmüller
Pubblicato in: Biomaterials, 2020, Pagina/e 120436, ISSN 0142-9612
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2020.120436

Building Complex Life Through Self-Organization

Autori: Mireille M.J.P.E. Sthijns, Vanessa L.S. LaPointe, Clemens A. van Blitterswijk
Pubblicato in: Tissue Engineering Part A, Numero 25/19-20, 2019, Pagina/e 1341-1346, ISSN 1937-3341
Editore: Mary Ann Liebert Inc.
DOI: 10.1089/ten.tea.2019.0208

The Role of Alpha Cells in the Self-Assembly of Bioengineered Islets

Autori: Fredrik C. Wieland, Mireille M.J.P.E. Sthijns, Thomas Geuens, Clemens A. van Blitterswijk, Vanessa L.S. LaPointe
Pubblicato in: Tissue Engineering Part A, 2020, ISSN 1937-3341
Editore: Mary Ann Liebert Inc.
DOI: 10.1089/ten.tea.2020.0080

Hydrogels that listen to cells: a review of cell-responsive strategies in biomaterial design for tissue regeneration

Autori: H. W. Ooi, S. Hafeez, C. A. van Blitterswijk, L. Moroni, M. B. Baker
Pubblicato in: Mater. Horiz., Numero 4/6, 2017, Pagina/e 1020-1040, ISSN 2051-6347
Editore: Royal Society of Chemistry
DOI: 10.1039/c7mh00373k

Redox regulation in regenerative medicine and tissue engineering: The paradox of oxygen

Autori: Mireille M.J.P.E. Sthijns, Clemens A. van Blitterswijk, Vanessa L.S. LaPointe
Pubblicato in: Journal of Tissue Engineering and Regenerative Medicine, 2018, ISSN 1932-6254
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/term.2730

A New Microengineered Platform for 4D Tracking of Single Cells in a Stem‐Cell‐Based In Vitro Morphogenesis Model

Autori: Pinak Samal, Philipp Maurer, Clemens Blitterswijk, Roman Truckenmüller, Stefan Giselbrecht
Pubblicato in: Advanced Materials, Numero 32/24, 2020, Pagina/e 1907966, ISSN 0935-9648
Editore: United Nations Industrial Developement Organization
DOI: 10.1002/adma.201907966

Oxygen and nutrient delivery in tissue engineering: Approaches to graft vascularization

Autori: Timo Rademakers, Judith M. Horvath, Clemens A. Blitterswijk, Vanessa L.S. LaPointe
Pubblicato in: Journal of Tissue Engineering and Regenerative Medicine, Numero 13/10, 2019, Pagina/e 1815-1829, ISSN 1932-6254
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/term.2932

Oxidative stress in pancreatic alpha and beta cells as a selection criterion for biocompatible biomaterials

Autori: Mireille M.J.P.E. Sthijns, Marlon J. Jetten, Sami G. Mohammed, Sandra M.H. Claessen, Rick H.W. de Vries, Adam Stell, Denise F.A. de Bont, Marten A. Engelse, Didem Mumcuoglu, Clemens A. van Blitterswijk, Patricia Y.W. Dankers, Eelco J.P. de Koning, Aart A. van Apeldoorn, Vanessa L.S. LaPointe
Pubblicato in: Biomaterials, Numero 267, 2021, Pagina/e 120449, ISSN 0142-9612
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2020.120449

Blastocyst-like structures generated solely from stem cells

Autori: Nicolas C. Rivron, Javier Frias-Aldeguer, Erik J. Vrij, Jean-Charles Boisset, Jeroen Korving, Judith Vivié, Roman K. Truckenmüller, Alexander van Oudenaarden, Clemens A. van Blitterswijk, Niels Geijsen
Pubblicato in: Nature, Numero 557/7703, 2018, Pagina/e 106-111, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-018-0051-0

Viscoelastic Oxidized Alginates with Reversible Imine Type Crosslinks: Self-Healing, Injectable, and Bioprintable Hydrogels

Autori: Shahzad Hafeez, Huey Ooi, Francis Morgan, Carlos Mota, Monica Dettin, Clemens van Blitterswijk, Lorenzo Moroni, Matthew Baker
Pubblicato in: Gels, Numero 4/4, 2018, Pagina/e 85, ISSN 2310-2861
Editore: MDPI
DOI: 10.3390/gels4040085

Other (1)

Chemically-defined induction of a primitive endoderm and epiblast-like niche supports post-implantation progression from blastoids

Autori: Erik J. Vrij, Yvonne S. Scholte op Reimer, Javier Frias Aldeguer, Isabel Misteli Guerreiro, Jop Kind, Bon-Kyoung Koo, Clemens A. van Blitterswijk, Nicolas C. Rivron
Pubblicato in: 2019
Editore: BioRxiv
DOI: 10.1101/510396