Respiratory Disease Screening with Dark-Field Computed Tomography

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Optimization of in vivo murine X-ray dark-field computed tomography

Author(s): Stephan Umkehrer, Lorenz Birnbacher, Rico Burkhardt, Maximilian von Teuffenbach, Ali Önder Yildirim, Daniela Pfeiffer, Julia Herzen, Franz Pfeiffer
Published in: Review of Scientific Instruments, Issue 90/10, 2019, Page(s) 103103, ISSN 0034-6748
Publisher: American Institute of Physics
DOI: 10.1063/1.5115436

Model-Based Iterative Reconstruction for Propagation-Based Phase-Contrast X-Ray CT including Models for the Source and the Detector

Author(s): Lorenz Hehn; Regine Gradl; Martin Dierolf; Kaye S. Morgan; David M. Paganin; Franz Pfeiffer
Published in: IEEE TMI, Issue 3, 2020, ISSN 0278-0062
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tmi.2019.2962615

Accurate effective atomic number determination with polychromatic grating-based phase-contrast computed tomography

Author(s): Lorenz Birnbacher, Marian Willner, Mathias Marschner, Daniela Pfeiffer, Franz Pfeiffer, Julia Herzen
Published in: Optics Express, Issue 26/12, 2018, Page(s) 15153, ISSN 1094-4087
Publisher: Optical Society of America
DOI: 10.1364/oe.26.015153

Two-shot X-ray dark-field imaging

Author(s): M. Marschner, L. Birnbacher, K. Mechlem, W. Noichl, A. Fehringer, M. Willner, K. Scherer, J. Herzen, P.B. Noël, F. Pfeiffer
Published in: Optics Express, Issue 24/23, 2016, Page(s) 27032, ISSN 1094-4087
Publisher: Optical Society of America
DOI: 10.1364/oe.24.027032

Correction of Motion Artifacts in Dark-Field Radiography of the Human Chest.

Author(s): Rafael C. Schick; Thomas Koehler; Wolfgang Noichl; Fabio De Marco; Konstantin Willer; Theresa Urban; Manuela Frank; Thomas Pralow; Ingo Maack; Sven Prevrhal; Bernd Lundt; Alexander A. Fingerle; Daniela Pfeiffer; Julia Herzen; Franz Pfeiffer
Published in: IEEE TMI, Issue 28, 2022, ISSN 0278-0062
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tmi.2021.3126492

Fabrication of gadolinium particle-based absorption gratings for neutron grating interferometry

Author(s): A. Gustschin, T. Neuwirth, A. Backs, M. Schulz, F. Pfeiffer
Published in: Review of Scientific Instruments, Issue 89/10, 2018, Page(s) 103702, ISSN 0034-6748
Publisher: American Institute of Physics
DOI: 10.1063/1.5047055

In-vivo X-ray dark-field computed tomography for the detection of radiation-induced lung damage in mice.

Author(s): Rico Burkhardt; Thomas Gora; Alexander A. Fingerle; Andreas Sauter; Felix Meurer; Florian T. Gassert; Sophie Dobiasch; Daniela Schilling; Annette Feuchtinger; Axel Walch; Gabriele Multhoff; Julia Herzen; Peter B. Noël; Ernst J. Rummeny; Stephanie E. Combs; Thomas Schmid; Franz Pfeiffer; Jan J. Wilkens
Published in: Physics and Imaging in Radiation Oncology, Issue 2, 2021, ISSN 0031-9155
Publisher: Institute of Physics Publishing
DOI: 10.1016/j.phro.2021.09.003

Spectral Differential Phase Contrast X-Ray Radiography

Author(s): Korbinian Mechlem, Thorsten Sellerer, Manuel Viermetz, Julia Herzen, Franz Pfeiffer
Published in: IEEE Transactions on Medical Imaging, Issue 39/3, 2020, Page(s) 578-587, ISSN 0278-0062
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tmi.2019.2932450

Fabrication of X-ray absorption gratings by centrifugal deposition of bimodal tungsten particles in high aspect ratio silicon templates

Author(s): Simon Pinzek; Alex Gustschin; Nikolai Gustschin; Manuel Viermetz; Franz Pfeiffer
Published in: Scientific Reports, Issue 4, 2022, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-022-08222-z

Qualitative and Quantitative Assessment of Emphysema Using Dark-Field Chest Radiography

Author(s): Theresa Urban; Florian T. Gassert; Manuela Frank; Konstantin Willer; Wolfgang Noichl; Philipp Buchberger; Rafael C. Schick; Thomas Koehler; Jannis H. Bodden; Alexander A. Fingerle; Andreas P. Sauter; Marcus R. Makowski; Franz Pfeiffer; Daniela Pfeiffer
Published in: Radiology, Issue 1, 2021, ISSN 0033-8419
Publisher: Radiological Society of North America
DOI: 10.1148/radiol.212025

X-ray Dark-Field Chest Imaging: Qualitative and Quantitative Results in Healthy Humans

Author(s): Florian T. Gassert; Theresa Urban; Manuela Frank; Konstantin Willer; Wolfgang Noichl; Philipp Buchberger; Rafael Schick; Thomas Koehler; Jens von Berg; Alexander A. Fingerle; Andreas Sauter; Marcus R. Makowski; Daniela Pfeiffer; Franz Pfeiffer
Published in: Radiology, Issue 15, 2021, ISSN 0033-8419
Publisher: Radiological Society of North America
DOI: 10.1148/radiol.2021210963

Dark-Field Chest Radiography of Combined Pulmonary Fibrosis and Emphysema

Author(s): Theresa Urban; Florian Gassert; Franz Pfeiffer; Daniela Pfeiffer
Published in: Radiology, Issue 4, 2022, ISSN 0033-8419
Publisher: Radiological Society of North America
DOI: 10.1148/ryct.220085

Direct Differentiation of Pathological Changes in the Human Lung Parenchyma With Grating-Based Spectral X-ray Dark-Field Radiography

Author(s): Kirsten Taphorn; Korbinian Mechlem; Thorsten Sellerer; Fabio De Marco; Manuel Viermetz; Franz Pfeiffer; Daniela Pfeiffer; Julia Herzen
Published in: IEEE TMI, Issue 29, 2019, ISSN 0278-0062
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tmi.2021.3061253

Dosimetry on first clinical dark‐field chest radiography

Author(s): Manuela Frank; Theresa Urban; Konstantin Willer; Wolfgang Noichl; Fabio De Marco; Rafael Schick; Bernhard Gleich; Alexander Schegerer; Ursula Lechel; Pascal Meyer; Juergen Mohr; Thomas Koehler; Andre Yaroshenko; Ingo Maack; Thomas Pralow; Roland Proksa; Bernhard Renger; Peter B. Noël; Alexander A. Fingerle; Daniela Pfeiffer; Ernst J. Rummeny; Julia Herzen; Franz Pfeiffer
Published in: Medical Physics, Issue 25, 2019, ISSN 0094-2405
Publisher: American Association of Physicists in Medicine
DOI: 10.1002/mp.15132

Simultaneous wood and metal particle detection on dark-field radiography

Author(s): Eva-Maria Braig, Lorenz Birnbacher, Florian Schaff, Lukas Gromann, Alexander Fingerle, Julia Herzen, Ernst Rummeny, Peter Noël, Franz Pfeiffer, Daniela Muenzel
Published in: European Radiology Experimental, Issue 2/1, 2018, ISSN 2509-9280
Publisher: Springer
DOI: 10.1186/s41747-017-0034-1

Assessment of intraductal carcinoma in situ (DCIS) using grating-based X-ray phase-contrast CT at conventional X-ray sources: An experimental ex-vivo study

Author(s): Karin Hellerhoff, Lorenz Birnbacher, Anikó Sztrókay-Gaul, Susanne Grandl, Sigrid Auweter, Marian Willner, Mathias Marschner, Doris Mayr, Maximilian F. Reiser, Franz Pfeiffer, Julia Herzen
Published in: PLOS ONE, Issue 14/1, 2019, Page(s) e0210291, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0210291

Tilted grating phase-contrast computed tomography using statistical iterative reconstruction

Author(s): Lorenz Birnbacher, Manuel Viermetz, Wolfgang Noichl, Sebastian Allner, Andreas Fehringer, Mathias Marschner, Maximilian von Teuffenbach, Marian Willner, Klaus Achterhold, Peter B. Noël, Thomas Koehler, Julia Herzen, Franz Pfeiffer
Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-018-25075-7

Quality and parameter control of X-ray absorption gratings by angular X-ray transmission

Author(s): Nikolai Gustschin, Alex Gustschin, Pascal Meyer, Manuel Viermetz, Philipp Riederer, Julia Herzen, Jürgen Mohr, Franz Pfeifferark
Published in: Optics Express, Issue 27/11, 2019, Page(s) 15943, ISSN 1094-4087
Publisher: Optical Society of America
DOI: 10.1364/oe.27.015943

Electron Density of Adipose Tissues Determined by Phase-Contrast Computed Tomography Provides a Measure for Mitochondrial Density and Fat Content

Author(s): Lorenz Birnbacher, Stefanie Maurer, Katharina Scheidt, Julia Herzen, Franz Pfeiffer, Tobias Fromme
Published in: Frontiers in Physiology, Issue 9, 2018, ISSN 1664-042X
Publisher: Frontiers Research Foundation
DOI: 10.3389/fphys.2018.00707

Dynamic <italic>In Vivo</italic> Chest X-ray Dark-Field Imaging in Mice

Author(s): R. Gradl, K. S. Morgan, M. Dierolf, C. Jud, L. Hehn, B. Gunther, W. Moller, D. Kutschke, L. Yang, T. Stoeger, D. Pfeiffer, B. Gleich, K. Achterhold, O. Schmid, F. Pfeiffer
Published in: IEEE Transactions on Medical Imaging, Issue 38/2, 2019, Page(s) 649-656, ISSN 0278-0062
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tmi.2018.2868999

3D grating-based X-ray phase-contrast computed tomography for high-resolution quantitative assessment of cartilage: An experimental feasibility study with 3T MRI, 7T MRI and biomechanical correlation

Author(s): Julia Herzen, Dimitrios C. Karampinos, Peter Foehr, Lorenz Birnbacher, Manuel Viermetz, Rainer Burgkart, Thomas Baum, Fabian Lohoefer, Moritz Wildgruber, Franz Schilling, Marian Willner, Mathias Marschner, Peter B. Noël, Ernst J. Rummeny, Franz Pfeiffer, Pia M. Jungmann
Published in: PLOS ONE, Issue 14/2, 2019, Page(s) e0212106, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0212106

Direct quantitative material decomposition employing grating-based X-ray phase-contrast CT

Author(s): Eva Braig, Jessica Böhm, Martin Dierolf, Christoph Jud, Benedikt Günther, Korbinian Mechlem, Sebastian Allner, Thorsten Sellerer, Klaus Achterhold, Bernhard Gleich, Peter Noël, Daniela Pfeiffer, Ernst Rummeny, Julia Herzen, Franz Pfeiffer
Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-018-34809-6

X-Ray Dark-field Imaging to Depict Acute Lung Inflammation in Mice

Author(s): Katharina Hellbach, Felix G. Meinel, Thomas M. Conlon, Konstantin Willer, Andre Yaroshenko, Astrid Velroyen, Margarita Braunagel, Sigrid Auweter, Maximilian F. Reiser, Oliver Eickelberg, Franz Pfeiffer, Ali Ö. Yildirim
Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-018-20193-8

Grating-based phase-contrast and dark-field computed tomography: a single-shot method

Author(s): Maximilian von Teuffenbach, Thomas Koehler, Andreas Fehringer, Manuel Viermetz, Bernhard Brendel, Julia Herzen, Roland Proksa, Ernst J. Rummeny, Franz Pfeiffer, Peter B. Noël
Published in: Scientific Reports, Issue 7/1, 2017, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-017-06729-4

Analysis and correction of bias induced by phase stepping jitter in grating-based X-ray phase-contrast imaging

Author(s): Fabio De Marco, Mathias Marschner, Lorenz Birnbacher, Peter Noël, Julia Herzen, Franz Pfeiffer
Published in: Optics Express, Issue 26/10, 2018, Page(s) 12707, ISSN 1094-4087
Publisher: Optical Society of America
DOI: 10.1364/oe.26.012707

In-vivo X-ray Dark-Field Chest Radiography of a Pig

Author(s): Lukas B. Gromann, Fabio De Marco, Konstantin Willer, Peter B. Noël, Kai Scherer, Bernhard Renger, Bernhard Gleich, Klaus Achterhold, Alexander A. Fingerle, Daniela Muenzel, Sigrid Auweter, Katharina Hellbach, Maximilian Reiser, Andrea Baehr, Michaela Dmochewitz, Tobias J. Schroeter, Frieder J. Koch, Pascal Meyer, Danays Kunka, Juergen Mohr, Andre Yaroshenko, Hanns-Ingo Maack, Thomas Pralow, Hendr
Published in: Scientific Reports, Issue 7/1, 2017, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-017-05101-w

Dose-compatible grating-based phase-contrast mammography on mastectomy specimens using a compact synchrotron source

Author(s): Elena Eggl, Susanne Grandl, Anikό Sztrόkay-Gaul, Martin Dierolf, Christoph Jud, Lisa Heck, Karin Burger, Benedikt Günther, Klaus Achterhold, Doris Mayr, Jan J. Wilkens, Sigrid D. Auweter, Bernhard Gleich, Karin Hellerhoff, Maximilian F. Reiser, Franz Pfeiffer, Julia Herzen
Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-018-33628-z

Trabecular bone anisotropy imaging with a compact laser-undulator synchrotron x-ray source

Author(s): Christoph Jud, Eva Braig, Martin Dierolf, Elena Eggl, Benedikt Günther, Klaus Achterhold, Bernhard Gleich, Ernst Rummeny, Peter Noël, Franz Pfeiffer, Daniela Muenzel
Published in: Scientific Reports, Issue 7/1, 2017, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-017-14830-x

Depiction of pneumothoraces in a large animal model using x-ray dark-field radiography

Author(s): Katharina Hellbach, Andrea Baehr, Fabio De Marco, Konstantin Willer, Lukas B. Gromann, Julia Herzen, Michaela Dmochewitz, Sigrid Auweter, Alexander A. Fingerle, Peter B. Noël, Ernst J. Rummeny, Andre Yaroshenko, Hanns-Ingo Maack, Thomas Pralow, Hendrik van der Heijden, Nataly Wieberneit, Roland Proksa, Thomas Koehler, Karsten Rindt, Tobias J. Schroeter, Juergen Mohr, Fabian Bamberg, Birgit Ertl-W
Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-018-20985-y

Brain Connectivity Exposed by Anisotropic X-ray Dark-field Tomography

Author(s): Matthias Wieczorek, Florian Schaff, Christoph Jud, Daniela Pfeiffer, Franz Pfeiffer, Tobias Lasser
Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-018-32023-y

Qualitative and Quantitative Imaging Evaluation of Renal Cell Carcinoma Subtypes with Grating-based X-ray Phase-contrast CT

Author(s): Margarita Braunagel, Lorenz Birnbacher, Marian Willner, Mathias Marschner, Fabio De Marco, Manuel Viermetz, Susan Notohamiprodjo, Katharina Hellbach, Sigrid Auweter, Vera Link, Christine Woischke, Maximilian F. Reiser, Franz Pfeiffer, Mike Notohamiprodjo, Julia Herzen
Published in: Scientific Reports, Issue 7/1, 2017, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/srep45400

Qualitative and Quantitative Evaluation of Structural Myocardial Alterations by Grating-Based Phase-Contrast Computed Tomography

Author(s): Susan Notohamiprodjo, Nicole Webber, Lorenz Birnbacher, Marian Willner, Manuel Viermetz, Julia Herzen, Mathias Marschner, Doris Mayr, Harald Bartsch, Tobias Saam, Sigrid Auweter, Franz Pfeiffer, Maximilian F. Reiser, Holger Hetterich
Published in: Investigative Radiology, Issue 53/1, 2018, Page(s) 26-34, ISSN 0020-9996
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/rli.0000000000000408

Revising the lower statistical limit of x-ray grating-based phase-contrast computed tomography

Author(s): Mathias Marschner, Lorenz Birnbacher, Marian Willner, Michael Chabior, Julia Herzen, Peter B. Noël, Franz Pfeiffer
Published in: PLOS ONE, Issue 12/9, 2017, Page(s) e0184217, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0184217

X-ray dark-field imaging of the human lung—A feasibility study on a deceased body

Author(s): Konstantin Willer, Alexander A. Fingerle, Lukas B. Gromann, Fabio De Marco, Julia Herzen, Klaus Achterhold, Bernhard Gleich, Daniela Muenzel, Kai Scherer, Martin Renz, Bernhard Renger, Felix Kopp, Fabian Kriner, Florian Fischer, Christian Braun, Sigrid Auweter, Katharina Hellbach, Maximilian F. Reiser, Tobias Schroeter, Juergen Mohr, Andre Yaroshenko, Hanns-Ingo Maack, Thomas Pralow, Hendrik van d
Published in: PLOS ONE, Issue 13/9, 2018, Page(s) e0204565, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0204565

High resolution laboratory grating-based X-ray phase-contrast CT

Author(s): Manuel Viermetz, Lorenz Birnbacher, Marian Willner, Klaus Achterhold, Franz Pfeiffer, Julia Herzen
Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-018-33997-5

Grating-based spectral X-ray dark-field imaging for correlation with structural size measures

Author(s): Kirsten Taphorn, Fabio De Marco, Jana Andrejewski, Thorsten Sellerer, Franz Pfeiffer, Julia Herzen
Published in: Scientific Reports, Issue 10/1, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-70011-3

Fabrication of x-ray absorption gratings via deep x-ray lithography using a conventional x-ray tube

Author(s): Simon Pinzek; Thomas Beckenbach; Manuel Viermetz; Pascal Meyer; Alex Gustschin; Jana Andrejewski; Nikolai Gustschin; Julia Herzen; Joachim Schulz; Franz Pfeiffer
Published in: Scientific Reports, Issue 3, 2022, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1117/1.jmm.20.4.043801

Modeling vibrations of a tiled Talbot-Lau interferometer on a clinical CT

Author(s): Clemens Schmid; Manuel Viermetz; Nikolai Gustschin; Wolfgang Noichl; Jakob Haeusele; Tobias Lasser; Thomas Koehler; Franz Pfeiffer
Published in: IEEE TMI, Issue 3, 2022, ISSN 0278-0062
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tmi.2022.3217662

Dual-Energy X-Ray Dark-Field Material Decomposition

Author(s): Thorsten Sellerer, Korbinian Mechlem, Ruizhi Tang, Kirsten Alexandra Taphorn, Franz Pfeiffer, Julia Herzen
Published in: IEEE Transactions on Medical Imaging, Issue 40/3, 2021, Page(s) 974-985, ISSN 0278-0062
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tmi.2020.3043303

Contrast-to-noise ratios and thickness-normalized, ventilation-dependent signal levels in dark-field and conventional in vivo thorax radiographs of two pigs

Author(s): De Marco, Fabio; Willer, Konstantin; Gromann, Lukas B.; Andrejewski, Jana; Hellbach, Katharina; Bähr, Andrea; Dmochewitz, Michaela; Koehler, Thomas; Maack, Hanns-Ingo; Pfeiffer, Franz; Herzen, Julia
Published in: PLOS ONE, Issue 14, 2019, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.5445/ir/1000137144

Joint Statistical Iterative Material Image Reconstruction for Spectral Computed Tomography Using a Semi-Empirical Forward Model

Author(s): Korbinian Mechlem, Sebastian Ehn, Thorsten Sellerer, Eva Braig, Daniela Munzel, Franz Pfeiffer, Peter B. Noel
Published in: IEEE Transactions on Medical Imaging, Issue 37/1, 2018, Page(s) 68-80, ISSN 0278-0062
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tmi.2017.2726687

Dark-field chest x-ray imaging: first experience in patients with alpha1-antitrypsin deficiency

Author(s): Gregor S. Zimmermann; Alexander A. Fingerle; Bernhard Renger; Karl-Ludwig Laugwitz; Hubert Hautmann; Andreas Sauter; Felix Meurer; Florian Tilman Gassert; Jannis Bodden; Christina Müller-Leisse; Martin Renz; Ernst J. Rummeny; Marcus R. Makowski; Konstantin Willer; Wolfgang Noichl; Fabio De Marco; Manuela Frank; Theresa Urban; Rafael C. Schick; Julia Herzen; Thomas Koehler; Bernhard Haller; Daniel
Published in: European Radiology, Issue 30, 2022, ISSN 0938-7994
Publisher: Springer Verlag
DOI: 10.1186/s41747-022-00263-3

X-ray Dark-field Chest Radiography of Lymphangioleiomyomatosis

Author(s): Florian Gassert; Franz Pfeiffer
Published in: Radiology, Issue 24, 2022, ISSN 0033-8419
Publisher: Radiological Society of North America
DOI: 10.1148/radiol.212490

A theoretical framework for comparing noise characteristics of spectral, differential phase-contrast and spectral differential phase-contrast X-ray imaging

Author(s): Korbinian Mechlem; Thorsten Sellerer; Manuel Viermetz; Julia Herzen; Franz Pfeiffer
Published in: PMB, Issue 27, 2019, ISSN 0031-9155
Publisher: Institute of Physics Publishing
DOI: 10.48550/arxiv.1910.00899

Technical design considerations of a human-scale Talbot-Lau interferometer for dark-field CT

Author(s): Manuel Viermetz; Nikolai Gustschin; Clemens Schmid; Jakob Haeusele; Peter B. Noel; Roland Proksa; Stefan Loscher; Thomas Koehler; Franz Pfeiffer
Published in: IEEE TMI, Issue 18, 2022, ISSN 0278-0062
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.36227/techrxiv.20715286.v1

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