Rules of self-organization and reengineering of liver tissue

Project Information

RULLIVER

Grant agreement ID: 695646

DOI

10.3030/695646

Project closed

EC signature date 12 July 2016

Start date 1 October 2016

End date 31 December 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 498 013,00

EU contribution

€ 2 498 013,00

Coordinated by

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (9)

Quantification of nematic cell polarity in three-dimensional tissues

Author(s): André Scholich, Simon Syga, Hernán Morales-Navarrete, Fabián Segovia-Miranda, Hidenori Nonaka, Kirstin Meyer, Walter de Back, Lutz Brusch, Yannis Kalaidzidis, Marino Zerial, Frank Jülicher, Benjamin M. Friedrich
Published in: PLOS Computational Biology, Issue 16/12, 2020, Page(s) e1008412, ISSN 1553-7358
Publisher: Plos Computational Biology
DOI: 10.1371/journal.pcbi.1008412

Bile canaliculi remodeling activates YAP via the actin cytoskeleton during liver regeneration.

Author(s): Kirstin Meyer; Hernán Morales-Navarrete; Sarah Seifert; Michaela Wilsch-Braeuninger; Uta Dahmen; Elly M. Tanaka; Lutz Brusch; Yannis Kalaidzidis; Yannis Kalaidzidis; Marino Zerial
Published in: Molecular Systems Biology, Issue 4, 2020, ISSN 1744-4292
Publisher: Nature Publishing Group
DOI: 10.15252/msb.20198985

Resilience of three-dimensional sinusoidal networks in liver tissue

Author(s): Jens Karschau, André Scholich, Jonathan Wise, Hernán Morales-Navarrete, Yannis Kalaidzidis, Marino Zerial, Benjamin M. Friedrich
Published in: PLOS Computational Biology, Issue 16/6, 2020, Page(s) e1007965, ISSN 1553-7358
Publisher: PLoS Comput Biol
DOI: 10.1371/journal.pcbi.1007965

A Predictive 3D Multi-Scale Model of Biliary Fluid Dynamics in the Liver Lobule

Author(s): Kirstin Meyer, Oleksandr Ostrenko, Georgios Bourantas, Hernan Morales-Navarrete, Natalie Porat-Shliom, Fabian Segovia-Miranda, Hidenori Nonaka, Ali Ghaemi, Jean-Marc Verbavatz, Lutz Brusch, Ivo Sbalzarini, Yannis Kalaidzidis, Roberto Weigert, Marino Zerial
Published in: Cell Systems, Issue 4/3, 2017, Page(s) 277-290.e9, ISSN 2405-4712
Publisher: Elsevier Inc.
DOI: 10.1016/j.cels.2017.02.008

Liquid-crystal organization of liver tissue

Author(s): Hernán Morales-Navarrete, Hidenori Nonaka, André Scholich, Fabián Segovia-Miranda, Walter de Back, Kirstin Meyer, Roman L Bogorad, Victor Koteliansky, Lutz Brusch, Yannis Kalaidzidis, Frank Jülicher, Benjamin M Friedrich, Marino Zerial
Published in: eLife, Issue 8, 2019, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.44860

Correlative single‐molecule localization microscopy and electron tomography reveals endosome nanoscale domains

Author(s): Christian Franke, Urska Repnik, Sandra Segeletz, Nicolas Brouilly, Yannis Kalaidzidis, Jean‐Marc Verbavatz, Marino Zerial
Published in: Traffic, Issue 20/8, 2019, Page(s) 601-617, ISSN 1398-9219
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/tra.12671

Hepatocyte apical bulkheads provide a mechanical means to oppose bile pressure

Author(s): Maarten P. Bebelman Matthew J. Bovyn Carlotta M. Mayer Julien Delpierre Ronald Naumann Nuno P. Martins Alf Honigmann Yannis Kalaidzidis Pierre A. Haas Marino Zerial
Published in: Journal of Cell Biology, Issue 222 (4), 2023, ISSN 1540-8140
Publisher: Rockefeller University Press
DOI: 10.1083/jcb.202208002

3D spatially-resolved geometrical and functional models of human liver tissue reveal new aspects of NAFLD progression

Author(s): Fabián Segovia-Miranda; Hernán Morales-Navarrete; Michael Kücken; V Moser; Sarah Seifert; Urska Repnik; Fabian Rost; Fabian Rost; Alexander Hendricks; Sebastian Hinz; Christoph Röcken; Dieter Lüthjohann; Yannis Kalaidzidis; Clemens Schafmayer; Lutz Brusch; Jochen Hampe; Marino Zerial
Published in: Nature medicine, Issue 4, 2019, ISSN 1078-8956
Publisher: Nature Publishing Group
DOI: 10.1101/572073

Anisotropic expansion of hepatocyte lumina enforced by apical bulkheads.

Author(s): Lenka Belicova; Urska Repnik; Julien Delpierre; Elzbieta Gralinska; Sarah Seifert; José Ignacio Valenzuela; Hernán Morales-Navarrete; Christian Franke; Helin Räägel; Evgeniya Shcherbinina; Tatiana Prikazchikova; Victor Koteliansky; Martin Vingron; Yannis Kalaidzidis; Timofei S. Zatsepin; Timofei S. Zatsepin; Marino Zerial
Published in: The Journal of Cell Biology, Issue 4, 2021, ISSN 0021-9525
Publisher: Rockefeller University Press
DOI: 10.1083/jcb.202103003