Towards prevention, early diagnosis, and noninvasive treatment of uterine leiomyomas through molecular classification

Project Information

MYCLASS

Grant agreement ID: 695727

DOI

10.3030/695727

Project closed

EC signature date 20 May 2016

Start date 1 June 2016

End date 31 May 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 499 099,00

EU contribution

€ 2 499 099,00

Coordinated by

HELSINGIN YLIOPISTO
Finland

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (5)

Deficient H2A.Z deposition is associated with genesis of uterine leiomyoma.

Author(s): Berta DG,Kuisma H,Välimäki N, Räisänen M,Jäntti M, Pasanen A,Karhu A,Kaukomaa J,Taira A, S,Lehtonen R,Mehine M,Vahteristo P, Jalkanen J,Sahu B, Ravantti J,Mäkinen N,Rajamäki K,Palin K,Taipale J,Heikinheimo O,Bützow R,Kaasinen E & Aaltonen LA at al.
Published in: Nature, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group

Global metabolomic profiling of uterine leiomyomas

Author(s): Hanna-Riikka Heinonen, Miika Mehine, Netta Mäkinen, Annukka Pasanen, Esa Pitkänen, Auli Karhu, Nanna S Sarvilinna, Jari Sjöberg, Oskari Heikinheimo, Ralf Bützow, Lauri A Aaltonen, Eevi Kaasinen
Published in: British Journal of Cancer, Issue 117/12, 2017, Page(s) 1855-1864, ISSN 0007-0920
Publisher: Nature Publishing Group
DOI: 10.1038/bjc.2017.361

Multiple clinical characteristics separate MED12-mutation-positive and -negative uterine leiomyomas

Author(s): Hanna-Riikka Heinonen, Annukka Pasanen, Oskari Heikinheimo, Tomas Tanskanen, Kimmo Palin, Jaana Tolvanen, Pia Vahteristo, Jari Sjöberg, Esa Pitkänen, Ralf Bützow, Netta Mäkinen, Lauri A. Aaltonen
Published in: Scientific Reports, Issue 7/1, 2017, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-017-01199-0

Discovery of potential causative mutations in human coding and noncoding genome with the interactive software BasePlayer

Author(s): Riku Katainen, Iikki Donner, Tatiana Cajuso, Eevi Kaasinen, Kimmo Palin, Veli Mäkinen, Lauri A. Aaltonen, Esa Pitkänen
Published in: Nature Protocols, Issue 13/11, 2018, Page(s) 2580-2600, ISSN 1754-2189
Publisher: Nature Publishing Group
DOI: 10.1038/s41596-018-0052-3

Genetic predisposition to uterine leiomyoma is determined by loci for genitourinary development and genome stability

Author(s): Niko Välimäki, Heli Kuisma, Annukka Pasanen, Oskari Heikinheimo, Jari Sjöberg, Ralf Bützow, Nanna Sarvilinna, Hanna-Riikka Heinonen, Jaana Tolvanen, Simona Bramante, Tomas Tanskanen, Juha Auvinen, Outi Uimari, Amjad Alkodsi, Rainer Lehtonen, Eevi Kaasinen, Kimmo Palin, Lauri A Aaltonen
Published in: eLife, Issue 7, 2018, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.37110