Cancer Diagnosis by Multiplex Protein Epitope Profiling

Informations projet

CANDLE

N° de convention de subvention: 697211

DOI

10.3030/697211

Projet clôturé

Date de signature de la CE 26 Août 2015

Date de début 1 Septembre 2015

Date de fin 31 Octobre 2015

Financé au titre de

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Coût total

€ 71 429,00

Contribution de l’UE

€ 50 000,00

Coordonné par

BIOSYSTEMS INTERNATIONAL KUTATO-, FEJLESZTO-, HASZNOSITO ES SZOLGALTATO KFT
Hungary

Periodic Reporting for period 1 - CANDLE (Cancer Diagnosis by Multiplex Protein Epitope Profiling)

Période du rapport: 2015-09-01 au 2015-10-31

Résumé du contexte et des objectifs généraux du projet

Cancer incidence is continuously increasing, making it a major concern of European governments. Cheaper, more sensitive and specific diagnostic tests are needed to foster early cancer diagnosis, thereby alleviating the impact of cancer on citizens’ lives and reducing overall cancer care costs. Biosystems International Kft. (BSI) developed a diagnostics technology based on plasma protein epitome biomarker panels, with promising results to meet these needs for breast (BC) and colon (CC) cancers. BSI’s novel biomarkers-based in vitro diagnostics will bring better health outcomes for the patient as earlier detection will increase survival and will reduce overall care costs contributing to the sustainability of the health care system.

Travail effectué depuis le début du projet jusqu’à la fin de la période considérée dans le rapport et principaux résultats atteints jusqu’à présent

In Phase I of CANDLE, BSI consolidated the business plan incorporating thorough market and commercialization studies for BC and CC and conducted a technology intellectual property evaluation. In order to execute the plan in Phase II, BSI recruited the critical experts and stakeholders and obtained expert opinions and intents for the design and development to complete clinical validation of the biomarker panels for BC and CC. The two cancers together represent 26.8 % of all cancer incidences in the EU. Clinically validated results obtained in CANDLE will enable BSI to seize the business opportunity and to maximize return on investments through higher royalties.

Progrès au-delà de l’état des connaissances et impact potentiel prévu (y compris l’impact socio-économique et les conséquences sociétales plus larges du projet jusqu’à présent)

BSI will develop blood tests that could become blockbusters in the BC and CC diagnostic markets. The optimal expected impact of successful early diagnostics (screening) in CC and BC is the reduction of mortality and increase in cancer-free survival. Based on our projections the increase in five-year survival could reach 5-20 % depending on the cancer type.

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