Objective
Environmental stresses are the primary causes of crop loss worldwide, reducing average yields for most major crop plants by more than 50%. To get an optimal adaptation to environmental threats, plants have evolved a variety of complex and efficient mechanisms of resistance, including compartmentalization of mRNAs and proteins in cytoplasmic structures known as Stress Granules (SGs). In these, mRNA molecules are stored, degraded or kept silent in order to prevent energy expenditure on producing useless proteins, promoting thus the translation of specific stress-responsive genes that lead to the recovery from stress. Despite their importance in cell fitness, the overall composition of SGs, as well as their assembly requirements and regulation remain largely unknown. Although SGs have been found to be evolutionary conserved between species, the current knowledge of how plant SGs can regulate and modulate the response to stress is still limited. The overall objective of this proposal is to increase our understanding of the fundamental function of SGs on the regulation of plant response to stress. To this end, a compendium of methodologies including genetic and cell biology will be implemented in order to identify and characterize mutants impaired in SGs formation, taking advantage of well-established photosynthetic model systems such as Arabidopsis thaliana and the green alga Chlamydomonas reinhardtii. Given that autophagy is a core mechanism that governs the regulation of SGs formation, disassembly or clearance in animal and yeast models, this molecular link will be studied in higher plants. It is anticipated that implementation of this project will provide novel insights into SGs biology, helping to enhance our knowledge on the modulation of stress responses. Besides, the proposed project is endowed of solid formative contents that will strengthen my previous experience, boosting my future scientific career and paving the way for closer scientific collaborations.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins proteomics
- natural sciences biological sciences microbiology phycology
- natural sciences biological sciences cell biology
- natural sciences mathematics pure mathematics mathematical analysis functional analysis
- natural sciences biological sciences molecular biology
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2015
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
28006 MADRID
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.