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Development of a cell-based system for high-throughput screening of antifibrotics

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Publications

Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells

Author(s): Ester Jiménez-Moreno, Zijian Guo, Bruno L. Oliveira, Inês S. Albuquerque, Annabel Kitowski, Ana Guerreiro, Omar Boutureira, Tiago Rodrigues, Gonzalo Jiménez-Osés, Gonçalo J. L. Bernardes
Published in: Angewandte Chemie International Edition, Issue 56/1, 2017, Page(s) 243-247, ISSN 1433-7851
DOI: 10.1002/anie.201609607

Inverse electron demand Diels–Alder reactions in chemical biology

Author(s): B. L. Oliveira, Z. Guo, G. J. L. Bernardes
Published in: Chemical Society Reviews, Issue 46/16, 2017, Page(s) 4895-4950, ISSN 0306-0012
DOI: 10.1039/c7cs00184c

Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents

Author(s): Barbara Bernardim, Pedro M.S.D. Cal, Maria J. Matos, Bruno L. Oliveira, Nuria Martínez-Sáez, Inês S. Albuquerque, Elizabeth Perkins, Francisco Corzana, Antonio C.B. Burtoloso, Gonzalo Jiménez-Osés, Gonçalo J. L. Bernardes
Published in: Nature Communications, Issue 7, 2016, Page(s) 13128, ISSN 2041-1723
DOI: 10.1038/ncomms13128

A Thioether-directed Palladium-cleavable Linker for Targeted Bioorthogonal Drug Decaging

Author(s): Benjamin Stenton, Bruno Oliveira, Maria Matos, Laura Sinatra, Gonçalo J. L. Bernardes
Published in: Chemical Science, 2018, ISSN 2041-6520
DOI: 10.1039/C8SC00256H

Chemo- and Regioselective Lysine Modification on Native Proteins

Author(s): Maria J. Matos, Bruno L. Oliveira, Nuria Martínez-Sáez, Ana Guerreiro, Pedro M. S. D. Cal, Jean Bertoldo, María Maneiro, Elizabeth Perkins, Julie Howard, Michael J. Deery, Justin M. Chalker, Francisco Corzana, Gonzalo Jiménez-Osés, Gonçalo J. L. Bernardes
Published in: Journal of the American Chemical Society, Issue 140/11, 2018, Page(s) 4004-4017, ISSN 0002-7863
DOI: 10.1021/jacs.7b12874

A Minimal, Unstrained S-Allyl Handle for Pre-Targeting Diels-Alder Bioorthogonal Labeling in Live Cells.

Author(s): Oliveira BL, Guo Z, Boutureira O, Guerreiro A, Jiménez-Osés G, Bernardes GJ
Published in: Angew Chem Int Ed Engl., Issue 55(47), 2016, Page(s) 14683-14687, ISSN 1521-3773
DOI: 10.1002/anie.201608438

A minimal, unstrained S-allyl handle for protein site-selective modification.

Author(s): Zijian Guo, Bruno L. Oliveira, Omar Boutureira, Ana Guerreiro, and Gonçalo J. L. Bernardes
Published in: EMBL conference 2016, Heidelberg, Germany., 2016