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An interdisciplinary approach to uncover the mechanisms of progression of cartilage damage at the cellular and tissue levels

Publications

Mechanobiological Model for Simulation of Injured Cartilage Degradation via Pro-Inflammatory Cytokines and Mechanical Stimulus

Author(s): Eskelinen, ASA. Tanska, P. Florea, C. Orozco, GA. Julkunen, P. Grodzinsky, AJ. Korhonen, RK.
Published in: PloS Computational Biology, 2020, ISSN 1553-734X
Publisher: Public Library of Science
DOI: 10.23729/0fec1760-d320-44f3-baae-608aee509dc5

Cyclic loading regime considered beneficial does not protect injured and interleukin-1-inflamed cartilage from post-traumatic osteoarthritis

Author(s): Eskelinen ASA, Florea C, Tanska P, Hung HK, Frank EH, Mikkonen S, Nieminen P, Julkunen P, Grodzinsky AJ, Korhonen RK
Published in: Journal of Biomechanics, Issue 00219290, 2022, ISSN 0021-9290
Publisher: Elsevier BV
DOI: 10.1016/j.jbiomech.2022.111181

A novel mechanobiological model can predict how physiologically relevant dynamic loading causes proteoglycan loss in mechanically injured articular cartilage

Author(s): Gustavo A. Orozco, Petri Tanska, Cristina Florea, Alan J. Grodzinsky, Rami K. Korhonen
Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-018-33759-3

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