An interdisciplinary approach to uncover the mechanisms of progression of cartilage damage at the cellular and tissue levels

Project Information

INpaCT

Grant agreement ID: 702586

DOI

10.3030/702586

Project closed

EC signature date 29 March 2016

Start date 1 January 2017

End date 30 August 2021

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 267 793,20

EU contribution

€ 267 793,20

Coordinated by

ITA-SUOMEN YLIOPISTO
Finland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (3)

Mechanobiological Model for Simulation of Injured Cartilage Degradation via Pro-Inflammatory Cytokines and Mechanical Stimulus

Author(s): Eskelinen, ASA. Tanska, P. Florea, C. Orozco, GA. Julkunen, P. Grodzinsky, AJ. Korhonen, RK.
Published in: PloS Computational Biology, 2020, ISSN 1553-734X
Publisher: Public Library of Science
DOI: 10.23729/0fec1760-d320-44f3-baae-608aee509dc5

Cyclic loading regime considered beneficial does not protect injured and interleukin-1-inflamed cartilage from post-traumatic osteoarthritis

Author(s): Eskelinen ASA, Florea C, Tanska P, Hung HK, Frank EH, Mikkonen S, Nieminen P, Julkunen P, Grodzinsky AJ, Korhonen RK
Published in: Journal of Biomechanics, Issue 00219290, 2022, ISSN 0021-9290
Publisher: Elsevier BV
DOI: 10.1016/j.jbiomech.2022.111181

A novel mechanobiological model can predict how physiologically relevant dynamic loading causes proteoglycan loss in mechanically injured articular cartilage

Author(s): Gustavo A. Orozco, Petri Tanska, Cristina Florea, Alan J. Grodzinsky, Rami K. Korhonen
Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-018-33759-3