Objective
Summary of Marie Curie Proposal for H2020-MSCA-IF-2015
“Bendable Bioplatform for Electrically stimulated Neuronal Differentiation”
With western countries aging faster, the neurodegenerative diseases like Parkinson’s, Alzheimer’s, Huntington’s etc. pose serious threat to quality of life, especially for people over 65 years[1]. In Europe, number of people suffering with dementia, which results from neuronal degeneration, is on the rise it is expected to be double in the next 20 Years[2]. The neuronal degeneration is irreversible[3] and currently the cell therapy for regeneration of neuron network is the only option to compensate such a loss. Recently, the induced pluripotent stem cell (iPSC) derived NSC therapy has come up as an excellent opportunity in treating of neuro degenerative diseases. However, proliferation and differentiation of iPS cell population in neuronal replacement therapies poses many technical challenges such as targeted neurite differentiation to compensate desired loss with controlled differentiation[4]. Traditionally, the neuronal differentiation of iPSC is performed using several transcriptional and growth factors, which are complex, expensive and non-scalable processes[5]. For this reason, the research for a simple, robust and scalable method for generating large number of mature, differentiated neuronal cell deserves top priority. In addition, an accurate on/off system for scalable proliferation and neuronal differentiation is pivotal for the development of implantable bioelectronics circuit suitable for in vivo application. It is believed that the electrical stimulus controlled neuronal differentiation of stem cells on a soft, bendable electro conductive substrate can be suitable for bioelectronics application and also for compensating neuronal loss in the degenerative disease or injuries. This project is an ambitious endeavour in this direction.
A bendable bioplatform will be developed for electrically stimulated neural differentiation t
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences computer and information sciences internet internet of things
- medical and health sciences basic medicine neurology dementia alzheimer
- natural sciences biological sciences cell biology
- medical and health sciences medical biotechnology cells technologies stem cells
- medical and health sciences basic medicine neurology parkinson
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
-
H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
See all projects funded under this programme -
H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
See all projects funded under this programme
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
See all projects funded under this funding scheme
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2015
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
G12 8QQ Glasgow
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.