Objective
Prenatal diagnosis of congenital abnormalities and intrauterine growth restriction (IGR) has become increasingly important thanks to the recent advancements in obstetrical ultrasound (US) imaging. An accurate and early diagnosis of fetal malformations and growth anomalies can improve fetal prognosis by allowing a treatment plan to be produced, enabling access to specialist units and appropriate treatments from birth. However, the diagnostic accuracy of US is limited due to its subjective assessment and inter-operator variability. On the other hand, magnetic resonance imaging (MRI) has the potential to offer a more detailed examination of the fetus. Unfortunately, its high cost, limited availability, and the difficulty in acquiring high quality 3D data due to constant fetal motion, hinder the widespread use of fetal MRI.
The MOUSIE project aims at improving the accuracy of fetal US examination by creating the first framework for multi-organ quantitative image analysis of the fetus. In particular, the specific goals of the MOUSIE project are: (1) development of new multi-organ MRI slice to volume reconstruction method able to provide comprehensive and relevant 3D inter-organ information of the fetal anatomy, including spine, lungs, liver and kidneys; (2) development of an US-based automated segmentation method, using a detailed MRI-US atlas of the anatomy of the fetus of 18-20 weeks of gestational age, that includes new structural similarity patterns and inter-organ shape models; (3) creation of a new generation of multi-organ fetal biomarkers based on the detailed and comprehensive anatomical information extracted from a unique database with more than 500 MRI-US scans, including healthy and pathological cases. By achieving these goals, MOUSIE will provide an innovative set of methods allowing for the first time quantitative, noninvasive, objective assessment of the fetal anatomy and growth, and thus address a long standing clinical need for such methodology.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine anatomy and morphology
- medical and health sciences clinical medicine obstetrics fetal medicine
- natural sciences computer and information sciences artificial intelligence generative artificial intelligence
- engineering and technology medical engineering diagnostic imaging magnetic resonance imaging
- medical and health sciences clinical medicine embryology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2015
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
SW7 2AZ London
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.