Objective Cardiovascular disease (CVD) incidence continues to rise at an alarming rate largely as a consequence of behavioural risk factors. The only way to tackle this epidemic is to implement preventive strategies before the disease appears. Current evidence suggests that conventional approaches are inadequate for promoting healthier lifestyles, and therefore implementation of novel methods is desperately needed. The research proposed under the acronym of CLIP (Comprehensive Lifestyle Intervention Project) will tackle novel approaches to CVD prevention based on the Personalized Medicine concept, considering the interactions between genetic and environmental factors of disease development.During the outgoing phase (24 months), the young Experienced Researcher (ER) will perform extensive and multidisciplinary training on innovative strategies for effective lifestyle modification in adults and children, and will undertake a specific study to identify genomic factors able to predict adult subjects who will benefit most from novel lifestyle interventions, thus permitting future tailored approaches. During the incoming phase (12 months) the ER will transfer the new methodology to Europe by carrying out a pilot lifestyle modification and genomic study program in adults in Spain. This experience will be enriched by the secondment in a private multinational company. Thus, the new abilities the ER will acquire from various areas will enable him to implement new programmes to attain primary CVD prevention, including the use of genomic-driven personalized approaches; and to become an independent group leader upon my return to Europe at the host institution. The long term impact of the CLIP will help to reduce the huge economic burden to society and healthcare systems associated with CVD treatment as it will directly contribute to Europe’s aim of fighting the CVD epidemic. Fields of science natural sciencesbiological sciencesgeneticsmedical and health sciencesclinical medicinecardiologycardiovascular diseasesarteriosclerosismedical and health scienceshealth sciencespersonalized medicinemedical and health sciencesbasic medicinephysiologymedical and health scienceshealth sciencesnutritionobesity Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Topic(s) MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) Call for proposal H2020-MSCA-IF-2015 See other projects for this call Funding Scheme MSCA-IF-GF - Global Fellowships Coordinator CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.) Net EU contribution € 257 191,20 Address CALLE MELCHOR FERNANDEZ ALMAGRO 3 28029 Madrid Spain See on map Region Comunidad de Madrid Comunidad de Madrid Madrid Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 257 191,20 Partners (1) Sort alphabetically Sort by Net EU contribution Expand all Collapse all Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI United States Net EU contribution € 0,00 Address ONE GUSTAVE L LEVY PLACE BOX 1075 10029 6574 New York See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 172 130,40