Objective
CONQUEST: Enabling advanced medical imaging
CONQUEST is formed around a new imaging technology platform. The basis is the newly developed nanoparticles function as contrast agents for a variety of imaging modalities that are presently used in healthcare such as ultrasound and MRI. In particular, the nanoparticles are a completely novel type of contrast agent for ultrasound imaging. The high stability and long shelf life of the particles combined with visibility in ultrasound could allow application of ultrasound imaging in areas currently dominated by more expensive, more difficult and slower imaging modalities such as MRI, PET or SPECT (nuclear imaging techniques). Moreover, ultrasound is already widely available, does not involve ionizing radiation and is the most “user-friendly” clinical imaging modality. Furthermore, the unique properties of the CONQUEST nanoparticles may allow its targeting to regions of inflammation, including malignant tumours and unstable atherosclerotic plaques. Initially, we will focus on the application of CONQUEST agents to the diagnosis of focal liver lesions. Currently, through the linked ERC StG, GMP-grade particles are available and approved for testing in a cell therapy clinical trial.
In all, at the end of this proposal, we expect to have solid in vivo proof of the viability of the agent in focal liver lesions (selected as our first application based on market research), and a strengthened IP position. This will put CONQUEST in a strong position to acquire the large amounts of funding necessary for full clinical validation, and the eventual introduction of new applications and new products.
Thus, with this technology platform we can create a new market (for multimodal imaging agents), improve efficiency and reduce costs in healthcare.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences physical sciences nuclear physics
- engineering and technology nanotechnology nano-materials
- engineering and technology medical engineering diagnostic imaging
- medical and health sciences medical biotechnology cells technologies
- natural sciences physical sciences acoustics ultrasound
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
ERC-POC - Proof of Concept Grant
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2015-PoC
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
6525 XZ Nijmegen
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.