Diabetes Approach by Multi-Organ-on-a-Chip

Project Information

DAMOC

Grant agreement ID: 714317

DOI 10.3030/714317

Project closed

EC signature date 14 December 2016

Start date 1 January 2017

End date 31 December 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 499 554,00

EU contribution € 1 499 554,00

Coordinated by

FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA
Spain

Publications

Peer reviewed articles (16)

The Synergy between Organ-on-a-Chip and Artificial Intelligence for the Study of NAFLD: From Basic Science to Clinical Research

Author(s): Francesco De Chiara, Ainhoa Ferret-Miñana, Javier Ramón-Azcón
Published in: Biomedicines, Issue 9/3, 2021, Page(s) 248, ISSN 2227-9059
Publisher: MDPI AG
DOI: 10.3390/biomedicines9030248

Cellulose-based scaffolds enhance pseudoislets formation and functionality

Author(s): Ferran Velasco-Mallorquí, Júlia Rodríguez-Comas, Javier Ramón-Azcón
Published in: Biofabrication, Issue 13/3, 2021, Page(s) 035044, ISSN 1758-5082
Publisher: IOS Press
DOI: 10.1088/1758-5090/ac00c3

New volumetric CNT-doped gelatin–cellulose scaffolds for skeletal muscle tissue engineering

Author(s): Ferran Velasco-Mallorquí, Juan M. Fernández-Costa, Luisa Neves, Javier Ramón-Azcón
Published in: Nanoscale Advances, Issue 2/7, 2020, Page(s) 2885-2896, ISSN 2516-0230
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0na00268b

Bioengineered in vitro skeletal muscles as new tools for muscular dystrophies preclinical studies

Author(s): Juan M. Fernández-Costa, Xiomara Fernández-Garibay, Ferran Velasco-Mallorquí, Javier Ramón-Azcón
Published in: Journal of Tissue Engineering, Issue 12, 2021, Page(s) 204173142098133, ISSN 2041-7314
Publisher: Sage-Hindawi Access to Research
DOI: 10.1177/2041731420981339

Islet-on-a-chip for the study of pancreatic β-cell function

Author(s): Júlia Rodríguez-Comas,Javier Ramón-Azcón
Published in: In vitro models, 2022, ISSN 2731-3441
Publisher: Springer Nature AG
DOI: 10.1007/s44164-021-00005-6

In Situ LSPR Sensing of Secreted Insulin in Organ-on-Chip

Author(s): María A. Ortega, Júlia Rodríguez-Comas, Ozlem Yavas, Ferran Velasco-Mallorquí, Jordina Balaguer-Trias, Victor Parra, Anna Novials, Joan M. Servitja, Romain Quidant, Javier Ramón-Azcón
Published in: Biosensors, Issue 11/5, 2021, Page(s) 138, ISSN 2079-6374
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/bios11050138

Bioengineered in vitro 3D model of myotonic dystrophy type 1 human skeletal muscle

Author(s): Xiomara Fernández-Garibay, María A Ortega, Estefanía Cerro-Herreros, Jordi Comelles, Elena Martínez, Rubén Artero, Juan M Fernández-Costa, Javier Ramón-Azcón
Published in: Biofabrication, Issue 13/3, 2021, Page(s) 035035, ISSN 1758-5082
Publisher: IOS Press
DOI: 10.1088/1758-5090/abf6ae

Intracellular Electrochemical Sensing

Author(s): Kosuke Ino, Yuji Nashimoto, Noriko Taira, Javier Ramon Azcon, Hitoshi Shiku
Published in: Electroanalysis, Issue 30/10, 2018, Page(s) 2195-2209, ISSN 1040-0397
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/elan.201800410

Muscle-on-a-chip with an on-site multiplexed biosensing system for in situ monitoring of secreted IL-6 and TNF-α

Author(s): María A. Ortega, Xiomara Fernández-Garibay, Albert G. Castaño, Francesco De Chiara, Alejandro Hernández-Albors, Jordina Balaguer-Trias, Javier Ramón-Azcón
Published in: Lab on a Chip, 2019, ISSN 1473-0197
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9lc00285e

Composite Biomaterials as Long-Lasting Scaffolds for 3D Bioprinting of Highly Aligned Muscle Tissue

Author(s): Andrea García-Lizarribar, Xiomara Fernández-Garibay, Ferran Velasco-Mallorquí, Albert G. Castaño, Josep Samitier, Javier Ramon-Azcon
Published in: Macromolecular Bioscience, Issue 18/10, 2018, Page(s) 1800167, ISSN 1616-5187
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.201800167

Microphysiological sensing platform for an in-situ detection of tissue-secreted cytokines

Author(s): Alejandro Hernández-Albors, Albert G. Castaño, Xiomara Fernández-Garibay, María Alejandra Ortega, Jordina Balaguer, Javier Ramón-Azcón
Published in: Biosensors and Bioelectronics: X, Issue 2, 2019, Page(s) 100025, ISSN 2590-1370
Publisher: Elsevier
DOI: 10.1016/j.biosx.2019.100025

High Protein Diet and Metabolic Plasticity in Non-Alcoholic Fatty Liver Disease: Myths and Truths

Author(s): Francesco De Chiara, Cynthia Ureta Checcllo, Javier Ramón Azcón
Published in: Nutrients, Issue 11/12, 2019, Page(s) 2985, ISSN 2072-6643
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu11122985

Direct and Label-Free Monitoring of Albumin in 2D Fatty Liver Disease Model using Plasmonic Nanogratings.

Author(s): Gerardo A. Lopez-Muñoz; Maria Alejandra Ortega; Ainhoa Ferret-Miñana; Francesco De Chiara; Javier Ramón-Azcón
Published in: Nanomaterials, Issue 1, 2020, ISSN 2079-4991
Publisher: MDPI AG
DOI: 10.20944/preprints202011.0492.v1

Disposable Polymeric Nanostructured Plasmonic Biosensors for Cell Culture Adhesion Monitoring

Author(s): Ainhoa Ferret-Miñana, Francesco De Chiara
Published in: Frontiers in Bioengineering and Biotechnology,, 2021, Page(s) 799325, ISSN 2296-4185
Publisher: Frontiers
DOI: 10.3389/fbioe.2021.799325

Plasmonic nanocrystals on polycarbonate substrates for direct and label-free biodetection of Interleukin-6 in bioengineered 3D skeletal muscles

Author(s): Gerardo A Lopez-Muñoz, Juan M Fernández-Costa, Maria Alejandra Ortega, Jordina Balaguer-Trias, Eduard Martin-Lasierra and Javier Ramón-Azcón
Published in: Nanophotonics, 2021, ISSN 2192-8614
Publisher: Walter de Gruyter GmbH 2022
DOI: 10.1515/nanoph-2021-0426

Collagen-Tannic Acid Spheroids for β-Cell Encapsulation Fabricated Using a 3D Bioprinter

Author(s): Laura Clua-Ferré,Francesco de Chiara,Júlia Rodríguez-Comas,Jordi Comelles,Elena Martinez,Amelie Luise Godeau,Ainhoa García-Alamán,Rosa Gasa,Javier Ramón-Azcón
Published in: Advanced Materials Technologies, 2022, ISSN 2365-709X
Publisher: Wiley
DOI: 10.1002/admt.202101696