Diabetes Approach by Multi-Organ-on-a-Chip

Informazioni relative al progetto

DAMOC

ID dell’accordo di sovvenzione: 714317

DOI 10.3030/714317

Progetto chiuso

Data della firma CE 14 Dicembre 2016

Data di avvio 1 Gennaio 2017

Data di completamento 31 Dicembre 2021

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 1 499 554,00

Contributo UE € 1 499 554,00

Coordinato da

FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA
Spain

Pubblicazioni

Peer reviewed articles (16)

The Synergy between Organ-on-a-Chip and Artificial Intelligence for the Study of NAFLD: From Basic Science to Clinical Research

Autori: Francesco De Chiara, Ainhoa Ferret-Miñana, Javier Ramón-Azcón
Pubblicato in: Biomedicines, Numero 9/3, 2021, Pagina/e 248, ISSN 2227-9059
Editore: MDPI AG
DOI: 10.3390/biomedicines9030248

Cellulose-based scaffolds enhance pseudoislets formation and functionality

Autori: Ferran Velasco-Mallorquí, Júlia Rodríguez-Comas, Javier Ramón-Azcón
Pubblicato in: Biofabrication, Numero 13/3, 2021, Pagina/e 035044, ISSN 1758-5082
Editore: IOS Press
DOI: 10.1088/1758-5090/ac00c3

New volumetric CNT-doped gelatin–cellulose scaffolds for skeletal muscle tissue engineering

Autori: Ferran Velasco-Mallorquí, Juan M. Fernández-Costa, Luisa Neves, Javier Ramón-Azcón
Pubblicato in: Nanoscale Advances, Numero 2/7, 2020, Pagina/e 2885-2896, ISSN 2516-0230
Editore: Royal Society of Chemistry
DOI: 10.1039/d0na00268b

Bioengineered in vitro skeletal muscles as new tools for muscular dystrophies preclinical studies

Autori: Juan M. Fernández-Costa, Xiomara Fernández-Garibay, Ferran Velasco-Mallorquí, Javier Ramón-Azcón
Pubblicato in: Journal of Tissue Engineering, Numero 12, 2021, Pagina/e 204173142098133, ISSN 2041-7314
Editore: Sage-Hindawi Access to Research
DOI: 10.1177/2041731420981339

Islet-on-a-chip for the study of pancreatic β-cell function

Autori: Júlia Rodríguez-Comas,Javier Ramón-Azcón
Pubblicato in: In vitro models, 2022, ISSN 2731-3441
Editore: Springer Nature AG
DOI: 10.1007/s44164-021-00005-6

In Situ LSPR Sensing of Secreted Insulin in Organ-on-Chip

Autori: María A. Ortega, Júlia Rodríguez-Comas, Ozlem Yavas, Ferran Velasco-Mallorquí, Jordina Balaguer-Trias, Victor Parra, Anna Novials, Joan M. Servitja, Romain Quidant, Javier Ramón-Azcón
Pubblicato in: Biosensors, Numero 11/5, 2021, Pagina/e 138, ISSN 2079-6374
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/bios11050138

Bioengineered in vitro 3D model of myotonic dystrophy type 1 human skeletal muscle

Autori: Xiomara Fernández-Garibay, María A Ortega, Estefanía Cerro-Herreros, Jordi Comelles, Elena Martínez, Rubén Artero, Juan M Fernández-Costa, Javier Ramón-Azcón
Pubblicato in: Biofabrication, Numero 13/3, 2021, Pagina/e 035035, ISSN 1758-5082
Editore: IOS Press
DOI: 10.1088/1758-5090/abf6ae

Intracellular Electrochemical Sensing

Autori: Kosuke Ino, Yuji Nashimoto, Noriko Taira, Javier Ramon Azcon, Hitoshi Shiku
Pubblicato in: Electroanalysis, Numero 30/10, 2018, Pagina/e 2195-2209, ISSN 1040-0397
Editore: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/elan.201800410

Muscle-on-a-chip with an on-site multiplexed biosensing system for in situ monitoring of secreted IL-6 and TNF-α

Autori: María A. Ortega, Xiomara Fernández-Garibay, Albert G. Castaño, Francesco De Chiara, Alejandro Hernández-Albors, Jordina Balaguer-Trias, Javier Ramón-Azcón
Pubblicato in: Lab on a Chip, 2019, ISSN 1473-0197
Editore: Royal Society of Chemistry
DOI: 10.1039/c9lc00285e

Composite Biomaterials as Long-Lasting Scaffolds for 3D Bioprinting of Highly Aligned Muscle Tissue

Autori: Andrea García-Lizarribar, Xiomara Fernández-Garibay, Ferran Velasco-Mallorquí, Albert G. Castaño, Josep Samitier, Javier Ramon-Azcon
Pubblicato in: Macromolecular Bioscience, Numero 18/10, 2018, Pagina/e 1800167, ISSN 1616-5187
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.201800167

Microphysiological sensing platform for an in-situ detection of tissue-secreted cytokines

Autori: Alejandro Hernández-Albors, Albert G. Castaño, Xiomara Fernández-Garibay, María Alejandra Ortega, Jordina Balaguer, Javier Ramón-Azcón
Pubblicato in: Biosensors and Bioelectronics: X, Numero 2, 2019, Pagina/e 100025, ISSN 2590-1370
Editore: Elsevier
DOI: 10.1016/j.biosx.2019.100025

High Protein Diet and Metabolic Plasticity in Non-Alcoholic Fatty Liver Disease: Myths and Truths

Autori: Francesco De Chiara, Cynthia Ureta Checcllo, Javier Ramón Azcón
Pubblicato in: Nutrients, Numero 11/12, 2019, Pagina/e 2985, ISSN 2072-6643
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu11122985

Direct and Label-Free Monitoring of Albumin in 2D Fatty Liver Disease Model using Plasmonic Nanogratings.

Autori: Gerardo A. Lopez-Muñoz; Maria Alejandra Ortega; Ainhoa Ferret-Miñana; Francesco De Chiara; Javier Ramón-Azcón
Pubblicato in: Nanomaterials, Numero 1, 2020, ISSN 2079-4991
Editore: MDPI AG
DOI: 10.20944/preprints202011.0492.v1

Disposable Polymeric Nanostructured Plasmonic Biosensors for Cell Culture Adhesion Monitoring

Autori: Ainhoa Ferret-Miñana, Francesco De Chiara
Pubblicato in: Frontiers in Bioengineering and Biotechnology,, 2021, Pagina/e 799325, ISSN 2296-4185
Editore: Frontiers
DOI: 10.3389/fbioe.2021.799325

Plasmonic nanocrystals on polycarbonate substrates for direct and label-free biodetection of Interleukin-6 in bioengineered 3D skeletal muscles

Autori: Gerardo A Lopez-Muñoz, Juan M Fernández-Costa, Maria Alejandra Ortega, Jordina Balaguer-Trias, Eduard Martin-Lasierra and Javier Ramón-Azcón
Pubblicato in: Nanophotonics, 2021, ISSN 2192-8614
Editore: Walter de Gruyter GmbH 2022
DOI: 10.1515/nanoph-2021-0426

Collagen-Tannic Acid Spheroids for β-Cell Encapsulation Fabricated Using a 3D Bioprinter

Autori: Laura Clua-Ferré,Francesco de Chiara,Júlia Rodríguez-Comas,Jordi Comelles,Elena Martinez,Amelie Luise Godeau,Ainhoa García-Alamán,Rosa Gasa,Javier Ramón-Azcón
Pubblicato in: Advanced Materials Technologies, 2022, ISSN 2365-709X
Editore: Wiley
DOI: 10.1002/admt.202101696