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Defining the role of the FGF – autophagy axis in bone physiology

Publications

MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B

Author(s): Laura Cinque, Chiara De Leonibus, Maria Iavazzo, Natalie Krahmer, Daniela Intartaglia, Francesco Giuseppe Salierno, Rossella De Cegli, Chiara Di Malta, Maria Svelto, Carmela Lanzara, Marianna Maddaluno, Luca Giorgio Wanderlingh, Antje K Huebner, Marcella Cesana, Florian Bonn, Elena Polishchuk, Christian A Hübner, Ivan Conte, Ivan Dikic, Matthias Mann, Andrea Ballabio, Francesca Sacco, Paolo Gruma
Published in: The EMBO Journal, 2020, ISSN 1460-2075
Publisher: EMBO Press
DOI: 10.15252/embj.2020105696

Phosphorylation of FAM134C by CK2 controls starvation-induced ER-phagy

Author(s): Di Lorenzo, Giorgia; Iavarone, Francescopaolo; Maddaluno, Marianna; Plata-Gómez, Ana Belén; Aureli, Simone; Quezada Meza, Camila Paz; Cinque, Laura; Palma, Alessandro; Reggio, Alessio; Cirillo, Carmine; Sacco, Francesca; Stolz, Alexandra; Napolitano, Gennaro; Marin, Oriano; Pinna, Lorenzo A; Ruzzene, Maria; Limongelli, Vittorio; Efeyan, Alejo; Grumati, Paolo; Settembre, Carmine; Pinna, Lorenzo A
Published in: Science Advances, 2022, ISSN 2375-2548
Publisher: AAAS
DOI: 10.1126/sciadv.abo1215

mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy

Author(s): Rosa Bartolomeo, Laura Cinque, Chiara De Leonibus, Alison Forrester, Anna Chiara Salzano, Jlenia Monfregola, Emanuela De Gennaro, Edoardo Nusco, Isabella Azario, Carmela Lanzara, Marta Serafini, Beth Levine, Andrea Ballabio, Carmine Settembre
Published in: Journal of Clinical Investigation, Issue 127/10, 2017, Page(s) 3717-3729, ISSN 0021-9738
Publisher: American Society for Clinical Investigation
DOI: 10.1172/JCI94130

A selective ER ‐phagy exerts procollagen quality control via a Calnexin‐ FAM 134B complex

Author(s): Alison Forrester, Chiara De Leonibus, Paolo Grumati, Elisa Fasana, Marilina Piemontese, Leopoldo Staiano, Ilaria Fregno, Andrea Raimondi, Alessandro Marazza, Gemma Bruno, Maria Iavazzo, Daniela Intartaglia, Marta Seczynska, Eelco Anken, Ivan Conte, Maria Antonietta De Matteis, Ivan Dikic, Maurizio Molinari, Carmine Settembre
Published in: The EMBO Journal, Issue 38/2, 2018, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.201899847

Defective collagen proteostasis and matrix formation in the pathogenesis of lysosomal storage disorders

Author(s): Settembre, Carmine; Cinque, Laura; Bartolomeo, Rosa; Di Malta, Chiara; De Leonibus, Chiara; Forrester, Alison
Published in: Matrix Biology, Issue October 2018, 2018, Page(s) 283-293, ISSN 0945-053X
Publisher: Elsevier BV
DOI: 10.1016/j.matbio.2018.06.001

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