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Defining the role of the FGF – autophagy axis in bone physiology

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Publications

mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy

Author(s): Rosa Bartolomeo, Laura Cinque, Chiara De Leonibus, Alison Forrester, Anna Chiara Salzano, Jlenia Monfregola, Emanuela De Gennaro, Edoardo Nusco, Isabella Azario, Carmela Lanzara, Marta Serafini, Beth Levine, Andrea Ballabio, Carmine Settembre
Published in: Journal of Clinical Investigation, 127/10, 2017, Page(s) 3717-3729, ISSN 0021-9738
Publisher: American Society for Clinical Investigation
DOI: 10.1172/JCI94130

A selective ER ‐phagy exerts procollagen quality control via a Calnexin‐ FAM 134B complex

Author(s): Alison Forrester, Chiara De Leonibus, Paolo Grumati, Elisa Fasana, Marilina Piemontese, Leopoldo Staiano, Ilaria Fregno, Andrea Raimondi, Alessandro Marazza, Gemma Bruno, Maria Iavazzo, Daniela Intartaglia, Marta Seczynska, Eelco Anken, Ivan Conte, Maria Antonietta De Matteis, Ivan Dikic, Maurizio Molinari, Carmine Settembre
Published in: The EMBO Journal, 38/2, 2018, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.201899847

Defective collagen proteostasis and matrix formation in the pathogenesis of lysosomal storage disorders

Author(s): Settembre, Carmine; Cinque, Laura; Bartolomeo, Rosa; Di Malta, Chiara; De Leonibus, Chiara; Forrester, Alison
Published in: Matrix Biology, October 2018, 2018, Page(s) 283-293, ISSN 0945-053X
Publisher: Elsevier BV
DOI: 10.1016/j.matbio.2018.06.001